Why is this medication prescribed?

Vumerity (diroximel fumarate) is a medication used for the treatment of relapsing forms of multiple sclerosis (MS). Multiple sclerosis is a chronic autoimmune disease that affects the central nervous system, leading to inflammation, demyelination (damage to the protective covering of nerve fibers), and various neurological symptoms.

Vumerity is classified as a disease-modifying therapy (DMT), and its active ingredient, diroximel fumarate, is believed to work by reducing inflammation and immune system activity, helping to slow down the progression of the disease and reduce the frequency of relapses.

How should this medicine be used?

Vumerity (diroximel fumarate) is a medication used to treat relapsing forms of multiple sclerosis (MS). It is important to follow the prescribed dosage and administration instructions provided by your healthcare provider. However, it’s crucial to note that medical advice should always take precedence, and the information provided here is for general informational purposes only.

Here are some general guidelines on how Vumerity is typically used:

• Dosage: The usual recommended dose of Vumerity is one 231 mg delayed-release capsule twice a day, taken orally.
• Administration: Vumerity should be taken with or without food. It’s important to swallow the capsule whole and not crush, chew, or sprinkle the contents on food. If you have difficulty swallowing the capsule, you can open it and mix the contents with applesauce. However, it’s important to consume the mixture right away without chewing.
• Consistency: Try to take Vumerity at the same times each day to maintain a consistent level of the medication in your system.
• Missed Dose: If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.
• Storage: Store Vumerity at room temperature, away from moisture and heat.

Always consult with your healthcare provider for personalized advice based on your specific medical condition and needs. They can provide guidance on how to best incorporate Vumerity into your overall treatment plan and address any specific concerns or considerations you may have.

Other uses for this medicine

As of last update, Vumerity is primarily indicated for the treatment of relapsing forms of MS. It is not intended for use in other conditions. Always follow your healthcare provider’s guidance regarding the use of this medication

What special precautions should I follow?

Regarding special precautions for Vumerity, it’s important to note that the following information is based on general guidelines, and individual circumstances may vary. Always follow the specific advice and instructions provided by your healthcare provider.

• Allergies: Inform your healthcare provider if you have a known allergy to diroximel fumarate or any of the other ingredients in Vumerity.
• Medical Conditions: Before starting Vumerity, provide your healthcare provider with a comprehensive medical history, including information about any existing medical conditions or allergies.
• Pregnancy and Breastfeeding: If you are pregnant, planning to become pregnant, or breastfeeding, discuss these circumstances with your healthcare provider. The potential risks and benefits of continuing or discontinuing Vumerity during pregnancy and breastfeeding should be carefully considered.
• Liver Function: Vumerity may affect liver function. Your healthcare provider may order periodic liver function tests to monitor for any signs of liver issues. If you have a history of liver problems, this should be discussed with your healthcare provider.
• Infections: Vumerity may suppress the immune system. Inform your healthcare provider about any signs of infection, and they will guide you on whether to continue or temporarily stop the medication during infections.
• Flushing and Gastrointestinal (GI) Effects: Vumerity can cause flushing (warmth and redness of the skin) and gastrointestinal effects such as nausea, diarrhea, and abdominal pain. Taking Vumerity with food or using aspirin 30 minutes before taking Vumerity may help reduce flushing.
• Other Medications: Inform your healthcare provider about all the medications, including over-the-counter drugs and supplements, that you are currently taking. Some medications may interact with Vumerity.

It’s essential to attend regular follow-up appointments with your healthcare provider to monitor your response to the medication and address any concerns or side effects that may arise. If you have specific questions or need more detailed information about Vumerity, consult with your healthcare provider or pharmacist, as they can provide the most current and tailored advice based on your individual health status.

What special dietary instructions should I follow?

Vumerity can be taken with or without food. Taking it with food may help reduce gastrointestinal side effects. If you experience flushing, taking aspirin 30 minutes before taking Vumerity may be recommended.

What should I do if I forget a dose?

If you forget to take a dose of Vumerity, follow these general guidelines:

• If it’s almost time for your next scheduled dose, skip the missed dose and take the next one at the regular time.
• Do not double up on doses to make up for a missed one.
• If you are unsure about what to do, contact your healthcare provider for guidance.

What side effects can this medication cause?

Vumerity (diroximel fumarate) is a medication used for the treatment of relapsing forms of multiple sclerosis. Like any medication, it can potentially cause side effects. The following list includes some common and less common side effects associated with Vumerity:

Common Side Effects:

• Flushing: This is a common side effect and may manifest as warmth, redness, itching, or a rash on the skin. Taking aspirin 30 minutes before taking Vumerity or with food may help reduce flushing.
• Gastrointestinal Effects: These may include nausea, diarrhea, and abdominal pain.
• Upper Respiratory Tract Infections: Infections of the nose, throat, and other upper respiratory tract symptoms may occur.

Less Common Side Effects:

• Liver Enzyme Elevation: Vumerity may affect liver function, and in some cases, it can lead to an elevation of liver enzymes. Regular monitoring of liver function may be recommended.
• Lymphopenia: A decrease in the number of certain white blood cells (lymphocytes) may occur.
• Allergic Reactions: While less common, allergic reactions to medications are possible. Seek medical attention if you experience symptoms such as rash, itching, swelling, severe dizziness, or difficulty breathing.

It’s important to note that not everyone will experience these side effects, and some individuals may experience side effects that are not listed here. Additionally, individual responses to medication can vary, and your healthcare provider will consider the overall benefit of the treatment in relation to potential side effects.

If you experience any side effects while taking Vumerity, it’s essential to report them to your healthcare provider. They can provide guidance on managing side effects or may adjust your treatment plan if necessary. Do not stop taking the medication without consulting your healthcare provider, as abruptly discontinuing disease-modifying therapies for multiple sclerosis can have adverse effects.

This information is based on knowledge, and there may have been updates or changes since then. Always refer to the most recent prescribing information or consult with your healthcare provider or pharmacist for the latest information on Vumerity and its potential side effects.

What should I know about storage and disposal of this medication?

Storage and Disposal of Vumerity:

Storage:

• Temperature: Store Vumerity at room temperature, away from excessive heat or cold.
• Container: Keep Vumerity in its original container or packaging.
• Moisture: Protect the medication from moisture.

Disposal:

• Disposal of Unused Medication: Follow local guidelines or consult with your pharmacist on how to dispose of any unused or expired medication.
• Do Not Flush: Do not flush Vumerity down the toilet unless instructed to do so.

In case of emergency/overdose

In case of an emergency or suspected overdose:

• Contact Emergency Services: Call emergency services (911 in the U.S.) immediately for assistance.
• Poison Control Center: Contact your local poison control center for guidance.
• Notify Healthcare Provider: Inform your healthcare provider as soon as possible.

What other information should I know?

• Follow Healthcare Provider’s Instructions: Take Vumerity exactly as prescribed by your healthcare provider. Do not adjust the dosage or stop taking it without consulting your healthcare provider.
• Regular Monitoring: Attend regular follow-up appointments with your healthcare provider for monitoring and assessment of your response to Vumerity.
• Communication with Healthcare Provider: Report any side effects, concerns, or changes in your health to your healthcare provider promptly.
• Medication Interactions: Inform your healthcare provider about all medications, including over-the-counter drugs and supplements, that you are currently taking, as some medications may interact with Vumerity.
• Pregnancy and Breastfeeding: If you are pregnant, planning to become pregnant, or breastfeeding, discuss these circumstances with your healthcare provider.
• Flushing and GI Effects: If you experience flushing, taking aspirin 30 minutes before taking Vumerity or with food may help. Report any gastrointestinal side effects to your healthcare provider.

Please note that the information provided here is based on knowledge, and there may have been updates or changes since then. Always refer to the most recent prescribing information and consult with your healthcare provider or pharmacist for the latest guidance on the use, storage, and disposal of Vumerity.