Why is this medication prescribed?

Umbralisib is a medication prescribed for the treatment of certain types of cancer, particularly hematologic malignancies. Umbralisib is a phosphoinositide 3-kinase (PI3K) inhibitor. The PI3K pathway is involved in regulating cell growth, survival, and proliferation. Abnormal activation of this pathway is associated with the development and progression of certain cancers. Umbralisib is used in the treatment of:

• Chronic Lymphocytic Leukemia (CLL): CLL is a type of cancer that affects the blood and bone marrow. Umbralisib may be prescribed to treat CLL.
• Small Lymphocytic Lymphoma (SLL): SLL is similar to CLL but primarily involves lymph nodes. Umbralisib may also be used in the treatment of SLL.

How should this medicine be used?

Umbralisib is typically administered orally in the form of tablets. Here are general guidelines on how Umbralisib is often used, but these may vary based on the specific details of your prescription:

• Dosage: The dosage of Umbralisib can vary depending on factors such as the type of cancer being treated, the patient’s overall health, and other individual considerations. Your healthcare provider will determine the appropriate dosage for you.
• Administration: Umbralisib tablets are usually taken by mouth with or without food. It’s important to swallow the tablets whole and not crush or chew them.
• Schedule: Umbralisib is typically taken once daily. Follow the schedule prescribed by your healthcare provider, and try to take the medication at the same time each day.
• Missed Dose: If you miss a dose, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and continue with your regular schedule. Do not double up on doses to make up for a missed one.
• Special Instructions: Your healthcare provider may provide specific instructions based on your medical condition and response to treatment. Always follow any additional guidance they provide.
• Monitoring: Regular follow-up appointments and monitoring are likely to be part of your treatment plan. Your healthcare provider will assess how you are responding to Umbralisib and may adjust the dosage if needed.

It’s crucial to communicate with your healthcare team about any side effects or concerns you may have during the course of your treatment. They can provide guidance on managing side effects and make adjustments to your treatment plan if necessary.

As medication guidelines can change, be sure to consult with your healthcare provider or refer to the most recent product information for the most accurate and up-to-date details on the use of Umbralisib.

Other uses for this medicine

Umbralisib is primarily used for specific medical conditions, such as certain types of cancers. It is essential to use Umbralisib only for the purpose prescribed by your healthcare provider. Do not use it for other conditions unless directed by your doctor.

What special precautions should I follow?

As for special precautions, it’s crucial to follow your healthcare provider’s guidance and discuss any concerns you may have. While the following precautions are general in nature and may not cover all potential considerations, they provide an overview:

• Pre-existing Conditions: Inform your healthcare provider about any pre-existing medical conditions, especially those related to the liver, kidneys, or any other significant health issues.
• Medication Interactions: Inform your healthcare provider about all the medications, vitamins, and supplements you are currently taking, as Umbralisib may interact with other drugs.
• Pregnancy and Breastfeeding: If you are pregnant, planning to become pregnant, or breastfeeding, discuss this with your healthcare provider. The potential risks and benefits of Umbralisib during pregnancy or breastfeeding should be considered.
• Infections: Umbralisib may increase the risk of infections. Inform your healthcare provider if you have any signs of infection, such as fever, chills, or persistent sore throat.
• Bleeding: Umbralisib may increase the risk of bleeding. Inform your healthcare provider if you experience unusual bleeding or bruising.
• Liver Function: Umbralisib can affect liver function. Regular monitoring of liver function may be necessary during treatment.
• Allergies: Inform your healthcare provider of any known allergies, including allergies to medications.

It’s important to attend all scheduled medical appointments, follow your healthcare provider’s instructions, and promptly report any side effects or concerns. If you have questions or need clarification about Umbralisib or its potential uses, consult with your healthcare provider, as they can provide personalized guidance based on your medical history and condition.

Since medical information can change, consult with your healthcare provider or refer to the most recent product information for the latest details on Umbralisib and its uses.

What special dietary instructions should I follow?

As of last update, there were no specific dietary restrictions mentioned for Umbralisib. However, it’s essential to follow your healthcare provider’s advice. If dietary considerations become relevant, your healthcare provider will provide specific guidance based on your individual health status.

What should I do if I forget a dose?

If you forget to take a dose of Umbralisib, follow these general guidelines:

• If it’s within 6 hours of the missed dose: Take the missed dose as soon as you remember.
• If it’s closer to the time of your next dose: Skip the missed dose and take your next dose at the regular time.

What side effects can this medication cause?

Umbralisib, like many medications, can cause side effects. The severity and specific side effects can vary from person to person. It’s important to note that the information provided here is based on knowledge, and new information or updates may have emerged since then. Always consult your healthcare provider or pharmacist for the most current and personalized information.

Common side effects of Umbralisib may include:

• Infections: Umbralisib can increase the risk of infections, such as upper respiratory tract infections. Notify your healthcare provider if you develop signs of infection, such as fever, chills, or persistent sore throat.
• Diarrhea: Diarrhea is a common side effect. Inform your healthcare provider if it becomes severe or persistent.
• Fatigue: Fatigue or weakness may occur. If this persists or becomes bothersome, discuss it with your healthcare provider.
• Nausea: Some people may experience nausea. If this is a concern, inform your healthcare provider.
• Neutropenia: Umbralisib may cause a decrease in the number of neutrophils (a type of white blood cell), increasing the risk of infection. Regular blood tests may be done to monitor your blood cell counts.
• Increased Liver Enzymes: Umbralisib can affect liver function, leading to elevated liver enzymes. Regular monitoring of liver function through blood tests is typically conducted.
• Bleeding: Umbralisib may increase the risk of bleeding. Inform your healthcare provider if you experience unusual bleeding or bruising.
• Rash: Skin reactions, including rash, may occur. If you develop a severe rash, notify your healthcare provider.

It’s important to promptly report any new or worsening symptoms to your healthcare provider, as they can provide guidance on managing side effects or adjust your treatment plan if needed.

This list is not exhaustive, and other side effects may occur. Additionally, the information provided here is not a substitute for professional medical advice. If you have specific concerns about Umbralisib or experience any side effects, contact your healthcare provider for guidance tailored to your individual health status.

What should I know about storage and disposal of this medication?

Storage of Umbralisib:

• Temperature: Store Umbralisib at room temperature, away from excessive heat and moisture.
• Container: Keep the medication in its original container to protect it from light.
• Keep out of reach: Store Umbralisib in a location that is out of reach of children and pets.

Disposal of Umbralisib:

• Consult a professional: Contact your local waste disposal facility, pharmacist, or healthcare provider for guidance on the proper disposal of unused or expired medications.
• Do not flush: Avoid flushing medications down the toilet unless instructed to do so, as this may contribute to environmental contamination.

In case of emergency/overdose

In case of a potential overdose or emergency, contact your local poison control center at 1-800-222-1222 or seek emergency medical attention immediately. Provide as much information as possible about the medication and the situation.

What other information should I know?

• Regular Follow-Up: Attend all scheduled follow-up appointments with your healthcare provider. Regular monitoring is often necessary to assess your response to Umbralisib and manage any potential side effects.
• Inform Healthcare Providers: Keep your healthcare provider informed about all medications, supplements, and over-the-counter drugs you are taking, as well as any changes in your health status.
• Patient Assistance Programs: If you face financial challenges in accessing medications, inquire about patient assistance programs that may be available to provide support.

Always consult with your healthcare provider or pharmacist for the most accurate and up-to-date information regarding the storage, disposal, and emergency procedures related to Umbralisib.