WARNING

Ultram ER, also known as tramadol extended-release, is a prescription medication used to manage moderate to moderately severe chronic pain in adults. While it can be effective for pain relief, it also comes with potential risks and side effects. It’s important to note that individual responses to medication can vary, and not everyone will experience these issues. Here are some potential risks associated with taking Ultram ER:

• Addiction and Dependence: Ultram ER belongs to the opioid analgesic class of medications, and like other opioids, there is a risk of dependence and addiction, especially if used improperly or for extended periods.
• Respiratory Depression: Opioids can suppress respiratory function, and high doses or misuse of Ultram ER may lead to respiratory depression, which can be life-threatening.
• Central Nervous System Effects: This medication can cause dizziness, drowsiness, and impaired cognitive function, affecting your ability to drive or operate machinery safely.
• Serotonin Syndrome: Tramadol, the active ingredient in Ultram ER, can increase serotonin levels. When combined with other medications that also affect serotonin levels, it can lead to serotonin syndrome, a potentially serious condition characterized by symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea.
• Seizures: Ultram ER may lower the seizure threshold, and the risk may be increased in individuals with a history of seizures or those taking certain medications.
• Hypotension: It can cause low blood pressure, especially when standing up from a sitting or lying position, leading to dizziness or fainting.
• Gastrointestinal Effects: Common side effects include nausea, constipation, and headache.

It’s crucial to take Ultram ER exactly as prescribed by your healthcare provider and to communicate any concerns or side effects promptly. Before starting any medication, discuss your medical history, current medications, and potential risks with your healthcare provider. They can provide personalized advice based on your specific health situation.

Why is this medication prescribed?

Ultram ER (tramadol extended-release) is prescribed to manage moderate to moderately severe chronic pain in adults when continuous, around-the-clock opioid analgesic therapy is needed for an extended period. Tramadol, the active ingredient in Ultram ER, works by binding to opioid receptors in the brain, altering the perception of pain and the response to it.

How should this medicine be used?

Here are some general guidelines on how Ultram ER should be used:

• Prescription and Dosage: Ultram ER is available only with a prescription from a healthcare provider. The dosage is individualized based on factors such as the severity of pain, the patient’s response, and their overall health.
• Extended-Release Formulation: Ultram ER is an extended-release formulation, meaning it provides a prolonged release of the medication over time. This allows for less frequent dosing compared to immediate-release tramadol.
• Dosing Schedule: The usual dosing schedule for Ultram ER is once daily. It should be taken at the same time each day, with or without food. The tablet should be swallowed whole and not crushed, chewed, or split.
• Individualized Treatment: Dosage adjustments may be necessary to achieve the desired level of pain control while minimizing side effects. Your healthcare provider will determine the appropriate dosage for your specific situation.
• Avoid Alcohol and Other Substances: It’s important to avoid alcohol and certain other substances while taking Ultram ER, as they can increase the risk of side effects and complications.
• Follow Healthcare Provider’s Instructions: Always follow your healthcare provider’s instructions regarding the use of Ultram ER. Do not alter the dosage or stop taking the medication without consulting your healthcare provider.
• Monitoring and Regular Check-ups: Regular follow-up appointments with your healthcare provider are important to monitor your response to the medication, adjust the dosage if necessary, and address any concerns or side effects.
• Risk of Dependence and Addiction: Ultram ER belongs to the opioid class of medications, and there is a risk of dependence and addiction. It should be used only as prescribed and under the close supervision of a healthcare professional.

It’s crucial to communicate openly with your healthcare provider about your pain levels, any side effects, or concerns you may have while taking Ultram ER. They can provide guidance on the proper use of the medication based on your individual health needs and circumstances.

Other uses for this medicine

While the primary use of Ultram ER is for managing moderate to moderately severe chronic pain, healthcare providers may consider its use for other conditions or purposes in certain cases. This decision should be made under the guidance of a healthcare professional.

What special precautions should I follow?

As for special precautions when using Ultram ER, here are some key considerations:

• Dependency and Addiction: Ultram ER belongs to the opioid class of medications, and there is a risk of dependence and addiction. It should be used with caution and only as prescribed by your healthcare provider.
• Seizures: Ultram ER may lower the seizure threshold, and the risk may be increased in individuals with a history of seizures or those taking medications that lower the seizure threshold.
• Serotonin Syndrome: Tramadol, the active ingredient in Ultram ER, can increase serotonin levels. Taking Ultram ER with other medications that affect serotonin levels can increase the risk of serotonin syndrome, a potentially serious condition.
• Respiratory Depression: Like other opioids, Ultram ER can suppress respiratory function, especially at higher doses or when misused. This can be life-threatening.
• Hypotension: Ultram ER may cause low blood pressure, especially when standing up from a sitting or lying position, leading to dizziness or fainting.
• Central Nervous System Effects: This medication can cause dizziness, drowsiness, and impaired cognitive function. It’s important to avoid activities that require mental alertness, such as driving or operating machinery, until you know how the medication affects you.
• Pregnancy and Breastfeeding: Ultram ER should be used with caution in pregnant or breastfeeding individuals, as tramadol can pass into breast milk and may have effects on a nursing infant.
• Interactions with Other Medications: Inform your healthcare provider about all medications, supplements, and herbal products you are taking, as Ultram ER may interact with certain substances.

Always follow your healthcare provider’s instructions carefully and inform them of your complete medical history to ensure safe and effective use of Ultram ER. If you have any concerns or experience adverse effects, contact your healthcare provider promptly.

What special dietary instructions should I follow?

There are no specific dietary restrictions associated with Ultram ER. However, it’s important to stay hydrated and maintain a balanced diet, as these factors can contribute to your overall well-being.

What should I do if I forget a dose?

• Take It as Soon as You Remember: If you forget a dose, take it as soon as you remember. If it’s almost time for your next dose, skip the missed one and continue with your regular schedule.
• Do Not Double Up: Do not take a double dose to make up for a missed one. Taking more than the prescribed amount can increase the risk of side effects and complications.
• Follow Healthcare Provider’s Guidance: If you are unsure about what to do, contact your healthcare provider or pharmacist for guidance. They can provide specific instructions based on your situation.

What side effects can this medication cause?

Ultram ER (tramadol extended-release) can cause various side effects, and individual responses to the medication may vary. Common side effects are generally mild, but some can be more severe. It’s crucial to report any unusual or persistent symptoms to your healthcare provider. Here is a list of potential side effects associated with Ultram ER:

Common Side Effects:

• Nausea: Feeling sick to your stomach.
• Constipation: Difficulty with bowel movements.
• Headache: Pain or discomfort in the head.
• Dizziness: Feeling lightheaded or unsteady.
• Drowsiness: Excessive sleepiness or fatigue.

Less Common Side Effects:

• Vomiting: Forceful expulsion of stomach contents.
• Itching: Unpleasant skin sensation leading to the desire to scratch.
• Sweating: Increased perspiration.
• Dry Mouth: Lack of moisture in the mouth.
• Diarrhea: Loose or watery stools.

Serious Side Effects (Seek Medical Attention):

• Seizures: Uncontrolled electrical activity in the brain.
• Serotonin Syndrome: Symptoms include confusion, hallucinations, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea.
• Respiratory Depression: Slow or shallow breathing.
• Hypotension: Low blood pressure, leading to dizziness or fainting.
• Allergic Reactions: Symptoms may include rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, or difficulty breathing.
• Adrenal Insufficiency: Symptoms include nausea, vomiting, loss of appetite, fatigue, weakness, dizziness, or low blood pressure.
• Withdrawal Symptoms: Abruptly stopping the medication may lead to withdrawal symptoms such as restlessness, watering eyes, runny nose, nausea, sweating, muscle aches, or diarrhea.

Remember that this is not an exhaustive list, and side effects can vary from person to person. If you experience any concerning symptoms while taking Ultram ER, contact your healthcare provider promptly. They can provide guidance on whether any adjustments to your treatment plan are necessary.

What should I know about storage and disposal of this medication?

Storage and Disposal of Ultram ER:

• Storage:
  • Store Ultram ER at room temperature away from light and moisture.
  • Keep it in a secure place, out of the reach of children and pets.
  • Do not store Ultram ER in the bathroom or kitchen.
• Disposal:
  • Dispose of unused or expired Ultram ER properly.
  • Follow any specific disposal instructions provided by your healthcare provider or local pharmacy.
  • Do not flush medications down the toilet unless instructed to do so.

In case of emergency/overdose

In case of emergency or overdose, seek immediate medical attention. Symptoms of overdose may include:

• Extreme drowsiness
• Slow or shallow breathing
• Loss of consciousness
• Seizures

What other information should I know?

• Follow Prescribed Dosage: Take Ultram ER exactly as prescribed by your healthcare provider. Do not alter the dosage without consulting them.
• Regular Monitoring: Attend follow-up appointments with your healthcare provider for monitoring and dose adjustments if necessary.
• Avoid Alcohol: Limit or avoid alcoholic beverages while taking Ultram ER, as alcohol can enhance the sedative effects of the medication.
• Inform Healthcare Provider: Inform your healthcare provider about all medications, supplements, and herbal products you are taking to avoid potential interactions.
• Driving and Machinery: Be cautious when engaging in activities that require mental alertness, such as driving or operating machinery, as Ultram ER can cause dizziness and drowsiness.
• Pregnancy and Breastfeeding: Consult your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding. Ultram ER should be used with caution in these situations.
• Allergic Reactions: If you develop signs of an allergic reaction, such as rash, itching, swelling, severe dizziness, or difficulty breathing, seek immediate medical attention.
• Inform Other Healthcare Providers: Make sure other healthcare providers are aware that you are taking Ultram ER, especially before undergoing surgery or other medical procedures.
• Keep a List of Medications: Maintain a list of all medications you are taking and carry it with you in case of emergencies.

Always consult with your healthcare provider or pharmacist for personalized advice and information based on your specific health condition and medical history. If you have any concerns about Ultram ER, do not hesitate to reach out to your healthcare provider for guidance.