WARNING

Tivorbex is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve pain and inflammation. Like all medications, it carries certain risks. Some of the potential risks of taking Tivorbex include:

• Gastrointestinal effects: NSAIDs like Tivorbex can increase the risk of stomach ulcers, bleeding, and perforation, particularly in individuals with a history of gastrointestinal issues.
• Cardiovascular risks: Long-term use of NSAIDs may elevate the risk of heart attack or stroke, especially in individuals with preexisting cardiovascular conditions.
• Renal complications: NSAIDs can impair kidney function, leading to fluid retention, high blood pressure, and in severe cases, kidney failure.
• Allergic reactions: Some people may experience allergic reactions to Tivorbex, ranging from mild skin rashes to more severe symptoms like difficulty breathing.
• Liver toxicity: Rarely, NSAIDs can cause liver damage or liver failure, especially with prolonged use or in individuals with underlying liver conditions.
• Interactions with other medications: Tivorbex can interact with other drugs, including certain blood thinners and antihypertensive medications, potentially increasing the risk of side effects or reducing the effectiveness of either medication.

It’s essential to use Tivorbex as directed by a healthcare professional, at the lowest effective dose for the shortest duration necessary to manage symptoms. Patients should also be monitored regularly for any signs of adverse effects, especially if they have preexisting medical conditions. If any concerning symptoms occur while taking Tivorbex, individuals should seek medical attention promptly.

Why is this medication prescribed?

Tivorbex is typically prescribed to relieve pain and inflammation associated with conditions such as osteoarthritis and rheumatoid arthritis in adults. It belongs to a class of medications known as nonsteroidal anti-inflammatory drugs (NSAIDs).

How should this medicine be used?

Here’s how Tivorbex is commonly used:

• Dosage: The dosage of Tivorbex varies depending on the individual’s condition, severity of symptoms, and medical history. It is typically taken orally, usually once daily, with or without food.
• Duration: Tivorbex is meant for short-term use to manage acute pain or inflammation. It should not be used for extended periods unless directed by a healthcare provider.
• Follow doctor’s instructions: It’s essential to follow the dosage instructions provided by your healthcare provider precisely. Do not exceed the recommended dose or take it more frequently than prescribed.
• Avoid alcohol: Consumption of alcohol while taking Tivorbex can increase the risk of gastrointestinal side effects. It’s best to avoid alcohol during the course of treatment.
• Regular monitoring: Patients taking Tivorbex should be monitored regularly by their healthcare provider for any signs of adverse effects or complications, especially if they have preexisting medical conditions such as cardiovascular disease or kidney impairment.
• Do not crush or chew: Tivorbex tablets should be swallowed whole with a glass of water. Do not crush, chew, or break the tablets unless specifically instructed by your doctor.
• Interaction with other medications: Inform your healthcare provider about all the medications, supplements, and herbal products you are taking, as Tivorbex may interact with certain drugs, including blood thinners and certain antidepressants.
• Discontinue if adverse effects occur: If you experience any concerning symptoms or side effects while taking Tivorbex, such as stomach pain, black or tarry stools, chest pain, or difficulty breathing, seek medical attention immediately and discontinue use until further guidance from your healthcare provider.

As with any medication, it’s crucial to use Tivorbex under the supervision of a healthcare professional and to discuss any questions or concerns you may have about its use.

Other uses for this medicine

Some other potential uses for Tivorbex include:

• Acute pain relief: Tivorbex may be prescribed for short-term management of acute pain, such as postoperative pain or pain due to injuries.
• Ankylosing spondylitis: It may also be used to relieve pain and inflammation associated with ankylosing spondylitis, a type of arthritis that primarily affects the spine.
• Other musculoskeletal conditions: Tivorbex may be prescribed for other musculoskeletal conditions causing pain and inflammation, as determined by a healthcare provider.

What special precautions should I follow?

Special precautions should be followed when using Tivorbex to minimize the risk of adverse effects and ensure safe and effective treatment:

• Medical history: Before starting Tivorbex, inform your healthcare provider about your complete medical history, including any allergies, gastrointestinal disorders, cardiovascular disease, kidney or liver problems, asthma, or other medical conditions.
• Risk assessment: Your healthcare provider will evaluate the benefits versus the risks of using Tivorbex, considering factors such as age, overall health, and potential interactions with other medications.
• Kidney function: NSAIDs like Tivorbex can affect kidney function, so regular monitoring of kidney function tests may be necessary, especially in individuals with preexisting kidney conditions or those at higher risk of kidney problems.
• Cardiovascular health: Tivorbex may increase the risk of heart attack or stroke, particularly in individuals with existing cardiovascular disease or risk factors. Your healthcare provider may closely monitor your cardiovascular health and recommend appropriate precautions.
• Gastrointestinal effects: NSAIDs can cause gastrointestinal side effects such as stomach ulcers, bleeding, and perforation. To minimize these risks, Tivorbex should be used at the lowest effective dose for the shortest duration necessary, and additional gastroprotective measures may be considered, such as taking Tivorbex with food or using gastroprotective medications.
• Avoid other NSAIDs: To reduce the risk of overdose and adverse effects, avoid taking other NSAIDs while using Tivorbex unless specifically instructed by your healthcare provider.
• Pregnancy and breastfeeding: Tivorbex should be avoided during the third trimester of pregnancy and is not recommended for use during breastfeeding, as it may harm the fetus or nursing infant.
• Alcohol consumption: Limit alcohol intake while taking Tivorbex, as alcohol can increase the risk of gastrointestinal side effects.
• Monitoring and follow-up: Regularly follow up with your healthcare provider while taking Tivorbex to monitor for any signs of adverse effects or complications and to adjust treatment as needed.

By following these precautions and guidelines, you can help ensure the safe and effective use of Tivorbex under the supervision of a healthcare professional.

What special dietary instructions should I follow?

Regarding dietary instructions for Tivorbex, it’s generally recommended to take it with food or milk to help reduce the risk of gastrointestinal side effects. However, specific dietary restrictions are not typically required unless advised by your healthcare provider based on your individual health status and medical history.

What should I do if I forget a dose?

If you forget to take a dose of Tivorbex, take it as soon as you remember. However, if it’s almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you’re unsure about what to do, consult your healthcare provider or pharmacist for guidance.

What side effects can this medication cause?

Tivorbex, like other NSAIDs (nonsteroidal anti-inflammatory drugs), can cause various side effects. Common side effects of Tivorbex include:

• Gastrointestinal effects: NSAIDs like Tivorbex can irritate the stomach lining, leading to symptoms such as stomach pain, indigestion, heartburn, nausea, vomiting, and diarrhea. In some cases, NSAIDs may also cause stomach ulcers, bleeding, or perforation, which can be serious and require medical attention.
• Cardiovascular effects: Long-term use of NSAIDs, including Tivorbex, may increase the risk of heart attack, stroke, or high blood pressure, especially in individuals with preexisting cardiovascular conditions or risk factors.
• Renal (kidney) effects: NSAIDs can impair kidney function, leading to fluid retention, electrolyte imbalances, and in severe cases, kidney failure. Symptoms of kidney problems may include decreased urine output, swelling in the legs or feet, and fatigue.
• Allergic reactions: Some people may experience allergic reactions to Tivorbex, ranging from mild skin rashes to more severe symptoms such as swelling of the face, throat, or tongue, difficulty breathing, or anaphylaxis (a life-threatening allergic reaction).
• Liver toxicity: Rarely, NSAIDs can cause liver damage or liver failure, particularly with prolonged use or in individuals with underlying liver conditions. Symptoms of liver toxicity may include jaundice (yellowing of the skin or eyes), dark urine, abdominal pain, or unusual fatigue.
• Central nervous system effects: Tivorbex may cause dizziness, headache, or drowsiness in some individuals. These effects can impair your ability to concentrate or operate machinery safely.
• Hematological effects: NSAIDs like Tivorbex may increase the risk of bleeding or bruising, particularly in individuals taking blood thinners or with bleeding disorders.
• Other side effects: Other potential side effects of Tivorbex include fluid retention, edema (swelling), ringing in the ears (tinnitus), and changes in blood counts.

It’s essential to be aware of these potential side effects and to report any concerning symptoms to your healthcare provider promptly. They can provide guidance on managing side effects and may adjust your treatment plan if necessary to minimize adverse effects. Additionally, if you experience severe or persistent side effects, seek medical attention immediately.

What should I know about storage and disposal of this medication?

Storage and Disposal:

• Storage: Keep Tivorbex tablets at room temperature, away from moisture and heat. Do not freeze. Store it in its original container, tightly closed, and out of reach of children and pets.
• Disposal: Dispose of Tivorbex tablets safely by following any specific disposal instructions provided by your healthcare provider or pharmacist. Do not flush medications down the toilet unless instructed to do so. Instead, check with your local pharmacy or waste disposal facility for proper disposal options.

In case of emergency/overdose

In case of an overdose of Tivorbex, seek emergency medical attention or call the Poison Help line at 1-800-222-1222 immediately. Overdose symptoms may include nausea, vomiting, stomach pain, dizziness, drowsiness, headache, blurred vision, ringing in the ears, confusion, seizures, or loss of consciousness.

What other information should I know?

• Inform all healthcare providers involved in your care about your use of Tivorbex, including dentists and pharmacists.
• Attend regular follow-up appointments with your healthcare provider to monitor your response to Tivorbex and assess for any potential side effects.
• Avoid prolonged exposure to sunlight and UV rays while taking Tivorbex, as it may increase the risk of sunburn.
• Keep a list of all medications you are taking, including prescription and over-the-counter drugs, herbal supplements, and vitamins, and share it with your healthcare provider to prevent potential drug interactions.
• If you are scheduled for surgery, inform your surgeon and anesthesiologist about your use of Tivorbex, as it may increase the risk of bleeding during the procedure.
• Follow your healthcare provider’s instructions carefully regarding the duration of Tivorbex treatment. Do not exceed the recommended dosage or duration of use without consulting your healthcare provider.
• If you experience any new or worsening symptoms while taking Tivorbex, such as stomach pain, chest pain, shortness of breath, swelling, or allergic reactions, seek medical attention promptly.

By following these guidelines and staying informed about Tivorbex, you can ensure safe and effective use of the medication under the guidance of your healthcare provider.