Why is this medication prescribed?

Rowasa is a brand name for a medication called mesalamine, which is used to treat inflammatory bowel diseases (IBD), such as ulcerative colitis. Ulcerative colitis is a chronic inflammatory condition that primarily affects the colon and rectum. Mesalamine is an anti-inflammatory drug that helps reduce inflammation in the digestive tract.

Rowasa is specifically formulated as a rectal suspension enema, and it is used to treat inflammation in the lower part of the colon and rectum. The medication works by inhibiting the production of inflammatory chemicals in the body.

How should this medicine be used?

Here are some key points about Rowasa:

• Indications:
  • Rowasa is primarily prescribed for the treatment of mild to moderately active ulcerative colitis, an inflammatory condition of the colon.
  • It is also used for the maintenance of remission in patients with ulcerative colitis.
• Usage:
  • Rowasa is administered rectally, meaning it is typically used as an enema. The medication comes in the form of a liquid enema that contains mesalamine.
  • The enema is usually administered once daily at bedtime.
  • Before using Rowasa, it is important to empty your bowels, and the enema should be retained for a specific period (usually several hours) to allow the medication to exert its effects.
• Administration:
  • The enema should be shaken well before use.
  • The patient should lie on their left side and insert the applicator tip into the rectum.
  • The medication is then slowly squeezed into the rectum.
• Dosage:
  • The dosage and duration of treatment with Rowasa will be determined by your healthcare provider based on the severity of your condition.
• Precautions:
  • It’s essential to follow your healthcare provider’s instructions and the instructions provided with the medication.
  • Inform your healthcare provider of any allergies or adverse reactions to medications, as well as any other medications or supplements you are currently taking.
  • If you experience any side effects or have concerns about the medication, contact your healthcare provider.

It’s crucial to note that individual patient instructions may vary, and it’s essential to follow the specific guidance provided by your healthcare provider or on the medication’s label. If you have any questions or concerns about using Rowasa, it’s recommended to consult with your healthcare professional for personalized advice.

Other uses for this medicine

Rowasa is primarily indicated for the treatment of mild to moderately active ulcerative colitis, but it may have some off-label uses as determined by your healthcare provider. Off-label use refers to using a medication for a purpose other than what it was originally approved for.

What special precautions should I follow?

While using Rowasa or any medication containing mesalamine, it’s essential to follow specific precautions to ensure safe and effective use. Here are some general precautions:

• Allergies: Inform your healthcare provider about any allergies you may have, especially if you are allergic to mesalamine or related medications.
• Medication Interactions: Inform your healthcare provider about all the medications, supplements, and over-the-counter drugs you are currently taking. Some medications may interact with mesalamine.
• Liver and Kidney Function: Mesalamine can affect liver and kidney function. Regular monitoring of liver and kidney function may be required during treatment.
• Pregnancy and Breastfeeding: Inform your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding. The benefits and risks of using mesalamine during pregnancy or breastfeeding should be discussed with your healthcare provider.
• Blood Disorders: Mesalamine can affect blood cell counts. Regular blood tests may be recommended to monitor for any changes in blood cell counts.
• Mesalamine Allergic Reaction: Mesalamine can cause an allergic reaction in some individuals. Seek medical attention immediately if you experience symptoms such as difficulty breathing, rash, itching, or swelling of the face, lips, or tongue.
• Mesalamine Hypersensitivity: Some patients may develop a hypersensitivity reaction to mesalamine, which can cause symptoms such as fever, headache, rash, and muscle pain. If these symptoms occur, contact your healthcare provider.

Always follow your healthcare provider’s instructions and advice regarding the use of Rowasa, and report any side effects or concerns promptly. It’s crucial to attend regular follow-up appointments as recommended by your healthcare provider to monitor your response to the medication and address any potential issues.

What special dietary instructions should I follow?

There are generally no specific dietary restrictions associated with Rowasa use. However, if you have specific dietary concerns or restrictions, it’s advisable to discuss them with your healthcare provider. A healthy, well-balanced diet is generally recommended for individuals with inflammatory bowel diseases.

What should I do if I forget a dose?

If you forget to use Rowasa at the prescribed time, follow these general guidelines:

• Use it as soon as you remember: If it is not too close to the time of your next scheduled dose, you can use the missed dose as soon as you remember.
• Skip the missed dose if it’s almost time for the next dose: If it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule.
• Do not double up: Do not take a double dose to make up for a missed one. Taking extra doses can increase the risk of side effects.

What side effects can this medication cause?

Rowasa (mesalamine) can cause side effects, and it’s important to be aware of these potential reactions. Not everyone will experience these side effects, and some individuals may have a higher tolerance for the medication. Common side effects may include:

• Rectal Irritation: Discomfort or irritation in the rectum may occur, especially when using the enema form of Rowasa.
• Headache: Some individuals may experience headaches while using mesalamine.
• Abdominal Pain: Abdominal pain or cramping may occur.
• Flatulence (Gas): Increased gas production is a possible side effect.
• Nausea or Vomiting: Some people may experience nausea or vomiting.
• Diarrhea: Diarrhea may occur as a side effect of mesalamine.
• Dizziness: Some individuals may experience dizziness.
• Fatigue: Feeling tired or fatigued is a possible side effect.
• Allergic Reactions: While rare, some people may be allergic to mesalamine, leading to symptoms such as rash, itching, swelling, severe dizziness, or difficulty breathing. Seek immediate medical attention if you experience these symptoms.
• Kidney or Liver Problems: In rare cases, mesalamine can affect kidney or liver function. Regular monitoring may be required.

It’s important to note that individual responses to medications vary, and not everyone will experience all of these side effects. Additionally, some side effects may subside as your body adjusts to the medication.

If you experience persistent or severe side effects, or if you notice any new or unusual symptoms, it’s crucial to contact your healthcare provider promptly. They can evaluate your condition and determine whether any adjustments to your treatment plan are necessary.

It’s also important to inform your healthcare provider of any pre-existing medical conditions or medications you are taking, as they can impact how your body responds to Rowasa. Always follow your healthcare provider’s instructions and attend regular follow-up appointments to monitor your response to the medication.

What should I know about storage and disposal of this medication?

Storage and Disposal of Rowasa:

• Storage:
  • Store Rowasa (mesalamine) as directed by the packaging or your healthcare provider.
  • Typically, enemas and other mesalamine formulations should be stored at room temperature away from light and moisture.
• Disposal:
  • Follow any specific disposal instructions provided by your healthcare provider or on the medication packaging.
  • Do not flush medications down the toilet unless instructed to do so.
  • If you have questions about the proper disposal of Rowasa or any medication, consult with your healthcare provider or a pharmacist.

In case of emergency/overdose

In the case of an emergency or suspected overdose, seek medical attention immediately. Symptoms of overdose may include severe headache, confusion, difficulty breathing, and seizures. Call your local poison control center or emergency room for guidance.

What other information should I know?

• Regular Follow-up: Attend regular follow-up appointments with your healthcare provider to monitor your response to Rowasa and discuss any concerns or changes in your condition.
• Inform Healthcare Provider: Keep your healthcare provider informed about any new medications, supplements, or over-the-counter drugs you may start taking.
• Allergies: Be aware of any allergies you may have, and inform your healthcare provider if you experience signs of an allergic reaction to Rowasa.
• Pregnancy and Breastfeeding: If you are pregnant, planning to become pregnant, or breastfeeding, discuss the risks and benefits of using Rowasa with your healthcare provider.
• Monitoring: Your healthcare provider may recommend periodic monitoring of liver and kidney function, as well as blood cell counts, while you are using Rowasa.
• Patient Education: Understand how to properly administer Rowasa, including the correct technique for using the enema, and follow your healthcare provider’s instructions closely.
• Dietary Considerations: While there are generally no specific dietary restrictions associated with Rowasa, maintaining a healthy, well-balanced diet is important for individuals with inflammatory bowel diseases.
• Contact Information: Keep contact information for your healthcare provider and, if applicable, your local poison control center readily available.

Always follow your healthcare provider’s advice and instructions for the use of Rowasa. If you have any questions or concerns, do not hesitate to reach out to your healthcare provider or pharmacist for clarification.