WARNING

ReVia, also known as naltrexone, is a medication used to treat alcohol and opioid dependence. While it can be effective in helping individuals overcome addiction, like any medication, it comes with potential risks and side effects. It’s crucial to note that individual responses to medications can vary, and a healthcare professional should always be consulted before starting or discontinuing any medication. Here are some potential risks associated with ReVia:

• Liver Function: ReVia can impact liver function, and regular monitoring is often required.
• Allergic Reactions: Some individuals may experience allergic reactions, such as rash, swelling, or difficulty breathing.
• Withdrawal Symptoms: If taken while still dependent on opioids, ReVia can precipitate withdrawal symptoms.
• Gastrointestinal Issues: Nausea, vomiting, abdominal pain, and constipation are potential side effects.
• Mood Changes: ReVia may lead to mood changes, depression, or thoughts of suicide.
• Interactions with Other Medications: ReVia can interact with other medications, necessitating careful consideration of its use in conjunction with other drugs.
• Overdose Risk: In case of a relapse, the protective effects of ReVia against opioids may be reduced, increasing the risk of overdose.
• Pregnancy and Breastfeeding: The safety of ReVia during pregnancy and breastfeeding is not well-established.

Remember, this is not an exhaustive list, and individual reactions can vary. Only a qualified healthcare professional can assess an individual’s specific situation and provide personalized advice. It’s important to follow their guidance and report any concerning symptoms promptly.

Why is this medication prescribed?

ReVia is a brand name for naltrexone, a medication used in the treatment of alcohol and opioid dependence. It is primarily prescribed to help individuals who are trying to overcome addiction to alcohol or opioids by reducing cravings and preventing the pleasurable effects of these substances.

How should this medicine be used?

Here’s some information on how ReVia is typically used:

• Dosage: The dosage of ReVia can vary depending on the individual’s specific situation and response to treatment. It is essential to follow the doctor’s prescription and instructions carefully.
• Initiation of Treatment: Before starting ReVia, individuals should be free of opioids for a certain period (7-10 days for short-acting opioids and longer for long-acting opioids) to prevent withdrawal symptoms. A naloxone challenge test may be done to ensure there are no opioids in the system.
• Oral Administration: ReVia is usually taken orally in the form of a tablet. The tablets are typically taken once a day with or without food.
• Monitoring: Regular medical monitoring is crucial during ReVia treatment, especially during the initial phase. This helps healthcare professionals ensure the medication is well-tolerated and effective.
• Comprehensive Treatment Plan: ReVia is often used as part of a comprehensive treatment plan that may include counseling, support groups, and other interventions to address the psychological and behavioral aspects of addiction.
• Adherence to Treatment: It is important for individuals to adhere to the prescribed treatment plan and attend all appointments with healthcare providers. Missing doses or stopping treatment prematurely can reduce the effectiveness of the medication.
• Caution with Opioid Analgesics: Since ReVia blocks the effects of opioids, caution should be exercised when using opioid-containing medications for pain relief. Higher doses of opioids are usually required to overcome the blocking effect of naltrexone, and this can increase the risk of overdose.

It’s crucial to note that the information provided here is a general overview, and individual cases may vary. Patients should always consult their healthcare provider for personalized advice regarding the use of ReVia or any other medication. Additionally, individuals with certain medical conditions or those taking other medications should inform their healthcare provider before starting ReVia.

Other uses for this medicine

While ReVia is primarily used for alcohol and opioid dependence, there is ongoing research into its potential use for other conditions. Some studies have explored its effectiveness in the treatment of certain psychiatric disorders, including impulse control disorders and certain forms of self-harm. However, these uses are still considered investigational, and ReVia is not widely prescribed for these purposes.

What special precautions should I follow?

Special Precautions for ReVia (Naltrexone):

• Liver Function Monitoring: Regular monitoring of liver function is important, especially for individuals with pre-existing liver conditions.
• Opioid-Free Period: Individuals should be opioid-free for at least 7-10 days before starting ReVia to avoid precipitating withdrawal symptoms.
• Withdrawal Risk: Patients should be aware of the risk of opioid withdrawal if they use opioids while taking ReVia.
• Pregnancy and Breastfeeding: The safety of ReVia during pregnancy and breastfeeding is not well-established. Discuss the potential risks and benefits with a healthcare provider if you are pregnant or breastfeeding.
• Other Medication Interactions: Inform your healthcare provider about all medications, including over-the-counter drugs and supplements, to check for potential interactions with ReVia.
• Allergic Reactions: Watch for signs of allergic reactions, such as rash, swelling, or difficulty breathing, and seek medical attention if they occur.
• Depression and Suicidal Thoughts: Patients should be monitored for changes in mood, depression, or suicidal thoughts. Notify your healthcare provider if any concerning symptoms arise.
• Patient Compliance: Adherence to the prescribed treatment plan is crucial for the effectiveness of ReVia. Follow your healthcare provider’s instructions carefully.

As always, it’s essential to consult with a healthcare professional for personalized advice and to discuss any specific medical conditions or concerns before starting ReVia or any medication.

What special dietary instructions should I follow?

There are generally no specific dietary restrictions associated with ReVia. However, it’s important to maintain a healthy and balanced diet, especially if you are recovering from substance abuse. A well-nourished body can support overall health and recovery.

What should I do if I forget a dose?

If you forget to take a dose of ReVia:

• If it’s close to the next scheduled dose: Skip the missed dose and take the next one at the regularly scheduled time.
• If there is ample time before the next dose: Take the missed dose as soon as you remember.
• Do not double up on doses: Do not take a double dose to make up for a missed one.
• Consult your healthcare provider: If you are unsure about what to do or if you have concerns about missed doses, contact your healthcare provider for guidance.

What side effects can this medication cause?

ReVia (naltrexone) may cause various side effects, and individual responses can vary. It’s essential to be aware of potential side effects and promptly report any concerning symptoms to your healthcare provider. Common side effects of ReVia include:

• Nausea and Vomiting: Gastrointestinal symptoms such as nausea and vomiting can occur, especially when starting the medication.
• Abdominal Pain: Some individuals may experience abdominal discomfort or pain.
• Headache: Headaches are a common side effect reported by individuals taking ReVia.
• Fatigue: Feeling tired or fatigued can be a side effect.
• Joint or Muscle Pain: Some individuals may experience joint or muscle pain.
• Loss of Appetite: A decreased appetite may occur in some individuals.
• Nervousness or Anxiety: ReVia may cause feelings of nervousness or anxiety in some people.
• Difficulty Sleeping (Insomnia): Insomnia or difficulty sleeping can be a side effect.
• Dizziness: Some individuals may experience dizziness.
• Irritability: ReVia may contribute to irritability in some individuals.
• Increased Liver Enzymes: Elevated liver enzymes have been reported, so regular monitoring of liver function is typically recommended.
• Allergic Reactions: Although rare, allergic reactions such as rash, itching, swelling, severe dizziness, or difficulty breathing can occur. Seek immediate medical attention if these symptoms occur.
• Depression and Suicidal Thoughts: Some individuals may experience changes in mood, depression, or thoughts of suicide. It’s important to monitor for these symptoms and seek help if needed.

It’s crucial to note that these are not exhaustive lists, and other side effects may occur. Additionally, the severity and duration of side effects can vary among individuals. Always consult with your healthcare provider if you experience any side effects or if you have concerns about the medication. They can provide guidance on managing side effects and, if necessary, adjust the treatment plan.

What should I know about storage and disposal of this medication?

Storage and Disposal of ReVia (Naltrexone):

• Storage:
  • Store ReVia at room temperature, away from moisture and heat.
  • Keep it in its original packaging or container.
  • Avoid storing it in the bathroom.
• Disposal:
  • Dispose of unused or expired medication properly.
  • Follow local guidelines or consult with your pharmacist on how to dispose of medications.
  • Do not flush medications down the toilet unless specifically instructed.

In case of emergency/overdose

If you suspect an overdose or experience severe symptoms, seek emergency medical attention. Symptoms of an overdose may include:

• Severe nausea and vomiting
• Blurred vision
• Confusion
• Hallucinations
• Loss of consciousness
• Seizures

What other information should I know?

• Regular Follow-ups: Attend scheduled follow-up appointments with your healthcare provider to monitor progress, discuss any concerns, and make adjustments to the treatment plan if necessary.
• Medical and Dental Procedures: Inform healthcare professionals, including dentists, about your use of ReVia before undergoing any medical or dental procedures. Naltrexone can interact with certain medications used for anesthesia or pain relief.
• Avoiding Opioids: While on ReVia, individuals should avoid using opioid-containing medications or illicit opioids, as it may lead to reduced efficacy and an increased risk of overdose.
• Inform Healthcare Providers: Make sure to inform any healthcare provider treating you about your use of ReVia, including emergency medical personnel.
• Patient Education: Understand the risks and benefits of ReVia, and follow your healthcare provider’s instructions carefully. If you have questions or concerns, do not hesitate to ask your healthcare provider.
• Alcohol and Other Substances: Discuss with your healthcare provider whether you should abstain from alcohol or any other substances while taking ReVia.
• Pregnancy and Breastfeeding: If you are pregnant, planning to become pregnant, or breastfeeding, discuss the potential risks and benefits of ReVia with your healthcare provider.

Always consult with your healthcare provider for personalized advice and information specific to your medical condition. This information is not a substitute for professional medical advice, diagnosis, or treatment.