Why is this medication prescribed?

Purixan (mercaptopurine) is a medication that belongs to a class of drugs known as antimetabolites. It is primarily prescribed to treat certain types of cancer, particularly acute lymphoblastic leukemia (ALL). ALL is a type of cancer that affects the white blood cells, and Purixan works by interfering with the growth and proliferation of cancer cells.

How should this medicine be used?

Here are some general guidelines on how Purixan may be used, but remember that individual circumstances may differ:

• Dosage: The dosage of Purixan is usually determined by the patient’s weight and medical condition. Your doctor will prescribe the appropriate dose for your specific case.
• Administration: Purixan is typically taken orally in the form of tablets. The tablets should be swallowed whole with a full glass of water. It’s important not to crush, break, or chew the tablets unless directed otherwise by your healthcare provider.
• Timing: The medication is often taken once daily. Your doctor will specify the exact time of day and whether you should take it with or without food. Follow these instructions carefully.
• Monitoring: Regular blood tests may be required to monitor your response to Purixan and to check for any potential side effects. Attend all scheduled appointments with your healthcare team to ensure proper monitoring.
• Compliance: It’s crucial to take Purixan exactly as prescribed by your doctor. Do not adjust the dosage or stop taking the medication without consulting your healthcare provider. Consistent adherence to the prescribed regimen is essential for the effectiveness of the treatment.
• Side Effects: Be aware of potential side effects and report any unusual symptoms or reactions to your healthcare team promptly. Common side effects may include nausea, vomiting, loss of appetite, and changes in blood cell counts.

Always consult with your healthcare provider for personalized advice and guidance on the use of Purixan. They will provide you with detailed instructions based on your medical history and specific treatment plan. If you have any concerns or questions about your medication, don’t hesitate to discuss them with your healthcare team.

Other uses for this medicine

Mercaptopurine, sold under the brand name Purixan among others, is primarily used for the treatment of certain types of cancer, especially acute lymphoblastic leukemia (ALL). Its use for other medical conditions is limited, and any use outside the scope of its intended purpose should be discussed with and approved by a healthcare professional.

What special precautions should I follow?

Special precautions should be taken when using Purixan, and it’s important to communicate openly with your healthcare provider. Here are some general precautions:

• Medical History: Inform your doctor of your complete medical history, including any pre-existing conditions, allergies, or previous reactions to medications.
• Pregnancy and Breastfeeding: If you are pregnant, planning to become pregnant, or breastfeeding, discuss this with your healthcare provider. Mercaptopurine may have potential risks to the fetus or nursing infant.
• Immunizations: Avoid live vaccines while taking mercaptopurine, as they may pose a risk. Discuss any planned vaccinations with your healthcare provider.
• Blood Cell Counts: Mercaptopurine can affect blood cell counts. Regular blood tests will likely be conducted to monitor for changes. Report any signs of infection, unusual bruising, or bleeding to your healthcare provider.
• Liver Function: Mercaptopurine may affect liver function. Regular liver function tests may be conducted during treatment.
• Interactions with Other Medications: Inform your doctor about all medications, including prescription, over-the-counter, and herbal supplements, that you are taking. Certain medications may interact with mercaptopurine, affecting its effectiveness or increasing the risk of side effects.
• Sun Exposure: Mercaptopurine may increase sensitivity to sunlight. Use sun protection measures, such as sunscreen and protective clothing, and avoid prolonged sun exposure.
• Gastrointestinal Issues: Mercaptopurine may cause nausea and vomiting. If you experience severe gastrointestinal symptoms, contact your healthcare provider.

Always follow your healthcare provider’s instructions and take the medication as prescribed. If you have questions or concerns about Purixan, do not hesitate to discuss them with your healthcare team. This information is not exhaustive, and specific precautions may vary based on individual health conditions and treatment plans.

What special dietary instructions should I follow?

• Food Intake: Mercaptopurine can be taken with or without food. Follow your doctor’s specific instructions regarding the timing of medication in relation to meals.
• Grapefruit Interaction: Avoid consuming grapefruit or grapefruit juice while taking mercaptopurine, as it may interact with the medication.
• Hydration: Drink plenty of fluids unless otherwise instructed by your healthcare provider.

What should I do if I forget a dose?

If you missed dose, follow these general guidelines:

• Missed Dose: If you miss a dose of Purixan, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule.
• Double Dosing: Do not take a double dose to make up for a missed one. If you are unsure about what to do, contact your healthcare provider for guidance.

What side effects can this medication cause?

Purixan (mercaptopurine) is a medication used in the treatment of certain types of cancer, primarily acute lymphoblastic leukemia (ALL). Like many medications, Purixan can cause side effects. It’s important to note that not everyone will experience these side effects, and their severity can vary. Always consult with your healthcare provider if you have concerns or are experiencing any unusual symptoms. Common side effects of Purixan may include:

• Nausea and Vomiting: These are common side effects and may be managed with anti-nausea medications as prescribed by your healthcare provider.
• Loss of Appetite: Some individuals may experience a decrease in appetite while taking Purixan.
• Bone Marrow Suppression: Mercaptopurine can affect the bone marrow, leading to a decrease in blood cell counts. This can result in an increased risk of infection, anemia, and easy bruising or bleeding. Regular blood tests are usually conducted to monitor blood cell counts.
• Liver Function Changes: Mercaptopurine may affect liver function, and liver function tests may be monitored during treatment.
• Pancreatitis: In rare cases, mercaptopurine may cause inflammation of the pancreas (pancreatitis), leading to abdominal pain, nausea, and vomiting.
• Allergic Reactions: Some individuals may experience allergic reactions, such as rash, itching, or swelling. Seek medical attention if you experience any signs of an allergic reaction.
• Increased Sun Sensitivity: Mercaptopurine may increase sensitivity to sunlight. Take precautions to protect yourself from sun exposure.
• Gastrointestinal Issues: Diarrhea and abdominal pain are possible side effects.
• Infections: Mercaptopurine can lower the body’s ability to fight infections. Contact your healthcare provider if you develop signs of infection, such as fever or persistent sore throat.

It’s important to report any side effects or changes in your health to your healthcare provider promptly. The benefits of the medication in treating the underlying condition are weighed against the potential risks and side effects. Your healthcare team will monitor your response to the medication and may adjust the treatment plan as needed.

This is not an exhaustive list of side effects, and individual experiences may vary. Always refer to the specific information provided by your healthcare provider or the medication’s prescribing information for a comprehensive understanding of potential side effects.

What should I know about storage and disposal of this medication?

Storage and Disposal:

• Storage Conditions: Store Purixan at room temperature away from light and moisture. Follow any specific storage instructions provided by your pharmacist or healthcare provider.
• Keep Out of Reach of Children: Store medications in a secure location, out of reach of children and pets.
• Disposal: Dispose of any unused or expired medication properly. Follow local regulations or guidelines for medication disposal. Do not flush medications down the toilet unless instructed to do so.

In case of emergency/overdose

• Seek Immediate Medical Attention: In case of an overdose or if you suspect someone has ingested more than the prescribed amount of Purixan, seek emergency medical attention or contact your local poison control center.
• Symptoms of Overdose: Symptoms of overdose may include severe nausea, vomiting, diarrhea, unusual bruising or bleeding, and signs of infection. Prompt medical attention is essential.

What other information should I know?

• Follow Healthcare Provider’s Instructions: Take Purixan exactly as prescribed by your healthcare provider. Do not adjust the dosage or stop taking the medication without consulting your doctor.
• Regular Monitoring: Be prepared for regular blood tests to monitor blood cell counts and liver function. Attend all scheduled appointments with your healthcare team.
• Inform Healthcare Provider: Inform your healthcare provider of any other medications, supplements, or herbal products you are taking to avoid potential drug interactions.
• Pregnancy and Breastfeeding: If you are pregnant, planning to become pregnant, or breastfeeding, discuss this with your healthcare provider, as mercaptopurine may have potential risks.
• Sun Protection: Due to the medication’s potential to increase sensitivity to sunlight, take precautions, such as using sunscreen and protective clothing, and minimize sun exposure.
• Contact Your Doctor for Side Effects: Report any side effects or changes in your health to your healthcare provider promptly.

Always refer to the specific information provided by your healthcare provider, pharmacist, or the medication’s prescribing information for comprehensive and accurate details. If you have any questions or concerns about Purixan, do not hesitate to discuss them with your healthcare team.