Why is this medication prescribed?

Phoslyra is a prescription medication used for the management of hyperphosphatemia in patients with end-stage renal disease (ESRD) who are on dialysis. Hyperphosphatemia is a condition characterized by elevated levels of phosphate in the blood, which commonly occurs in individuals with kidney problems.

Phoslyra contains calcium acetate, which works by binding to dietary phosphate in the gastrointestinal tract, preventing its absorption and helping to lower phosphate levels in the blood.

How should this medicine be used?

Phoslyra (calcium acetate) is a prescription medication used to treat hyperphosphatemia, particularly in patients with end-stage renal disease (ESRD) who are undergoing dialysis. It’s important to note that specific dosage and administration instructions may vary based on individual patient factors, and you should follow the guidance provided by your healthcare provider. However, here are some general guidelines:

• Dosage: The recommended dosage of Phoslyra is usually determined by your healthcare provider based on your individual needs and response to the medication.
• Administration: Phoslyra is an oral solution and is typically taken with meals or as directed by your healthcare provider. It is important to shake the bottle well before using to ensure proper mixing of the medication.
• Measuring the Dose: Use the measuring device provided with the medication or as instructed by your healthcare provider to measure the correct dose. Do not use household teaspoons or tablespoons, as they may not provide accurate measurements.
• Consistency: Take Phoslyra consistently as prescribed by your healthcare provider. It is important not to miss doses, and you should follow the schedule recommended by your healthcare professional.
• Monitoring: Your healthcare provider may monitor your blood phosphate levels regularly to assess the effectiveness of the medication. Adjustments to the dosage may be made based on these monitoring results.
• Interactions: Inform your healthcare provider about all the medications, supplements, and over-the-counter drugs you are taking, as certain medications may interact with Phoslyra.
• Adverse Effects: Be aware of potential side effects and contact your healthcare provider if you experience any unusual symptoms or adverse reactions.

It is crucial to follow your healthcare provider’s instructions and seek clarification on any questions or concerns you may have about the use of Phoslyra. Never adjust the dosage or stop taking the medication without consulting your healthcare provider. If you have specific questions about your prescription or dosage, it’s recommended to reach out to your healthcare professional or pharmacist for personalized guidance.

Other uses for this medicine

As of last update, Phoslyra is primarily prescribed for the management of hyperphosphatemia associated with end-stage renal disease in patients undergoing dialysis. Any other uses would be considered off-label and should only be done under the guidance of a healthcare professional.

What special precautions should I follow?

As for special precautions, it’s crucial to follow your healthcare provider’s advice and inform them of your medical history, especially if you have:

• Allergies: Inform your healthcare provider if you are allergic to calcium acetate or any other medications.
• Kidney Function: Since Phoslyra is used in patients with kidney problems, it’s important to discuss your kidney function with your healthcare provider. They may need to adjust the dosage based on your renal function.
• Calcium Levels: High levels of calcium in the blood (hypercalcemia) may occur with the use of calcium-containing medications. Your healthcare provider will monitor your calcium levels to ensure they are within the normal range.
• Phosphate Levels: Regular monitoring of blood phosphate levels is typically done to assess the effectiveness of Phoslyra and adjust the dosage as needed.
• Medication Interactions: Inform your healthcare provider about all medications, supplements, and over-the-counter drugs you are taking, as certain medications may interact with Phoslyra.
• Pregnancy and Breastfeeding: If you are pregnant, planning to become pregnant, or breastfeeding, discuss the potential risks and benefits of Phoslyra with your healthcare provider.

Always take Phoslyra exactly as prescribed by your healthcare provider and follow their recommendations for dosage and administration. If you experience any side effects or have concerns about the medication, contact your healthcare provider promptly. This information is based on the knowledge, and it’s advisable to consult with a healthcare professional for the most current and personalized advice.

What special dietary instructions should I follow?

Special Dietary Instructions for Phoslyra:

• Take with Meals: Phoslyra is typically taken with meals or as directed by your healthcare provider. This helps control phosphate levels during digestion.
• Phosphate-Restricted Diet: Your healthcare provider may recommend a phosphate-restricted diet to complement the effects of Phoslyra. This may involve limiting intake of high-phosphate foods such as dairy products, certain meats, and processed foods.
• Fluid Intake: Adequate fluid intake is important to help flush out excess phosphate. However, individual fluid restrictions may apply, and your healthcare provider will provide guidance.

What should I do if I forget a dose?

• Take the Missed Dose as Soon as Possible: If you forget a dose, take it as soon as you remember. However, if it’s almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule.
• Do Not Double Up: Do not take a double dose to make up for a missed one. Taking more than the prescribed amount can lead to adverse effects.
• Consult Your Healthcare Provider: If you have concerns or questions about missed doses, contact your healthcare provider for guidance.

What side effects can this medication cause?

Phoslyra (calcium acetate) is generally well-tolerated, but like any medication, it may cause side effects in some individuals. It’s important to note that not everyone will experience these side effects, and some individuals may experience side effects that are not listed here. If you are prescribed Phoslyra and have concerns about potential side effects, it’s essential to discuss them with your healthcare provider. Common side effects may include:

• Constipation: Calcium-containing medications, such as Phoslyra, can sometimes lead to constipation. Adequate fluid intake and dietary fiber may help alleviate this side effect.
• Nausea and Vomiting: Some individuals may experience nausea or vomiting as a side effect of Phoslyra.
• Hypercalcemia: Since Phoslyra contains calcium, there is a risk of elevated calcium levels in the blood (hypercalcemia). Symptoms of hypercalcemia may include nausea, vomiting, constipation, loss of appetite, increased thirst, increased urination, confusion, and fatigue.
• Hypophosphatemia: In some cases, Phoslyra may cause low levels of phosphate in the blood (hypophosphatemia), which can lead to symptoms such as weakness, muscle pain, and bone pain.
• Metallic Taste: Some individuals may experience a metallic taste in the mouth.
• Allergic Reactions: While rare, allergic reactions to medications can occur. Seek medical attention if you experience symptoms such as rash, itching, swelling, severe dizziness, or difficulty breathing.

It’s important to report any unusual or severe side effects to your healthcare provider promptly. Additionally, inform your healthcare provider about all medications, supplements, and over-the-counter drugs you are taking, as certain medications may interact with Phoslyra.

This list is not exhaustive, and individual responses to medications can vary. Always follow your healthcare provider’s instructions, report any side effects promptly, and attend regular follow-up appointments to monitor your response to the medication. If you have specific concerns about Phoslyra, consult with your healthcare provider for personalized guidance.

What should I know about storage and disposal of this medication?

Storage and Disposal of Phoslyra:

• Storage:
  • Store Phoslyra at room temperature, away from light and moisture.
  • Keep the medication out of reach of children and pets.
  • Do not freeze the liquid.
• Disposal:
  • Follow local regulations or guidelines for the disposal of medications.
  • Do not flush Phoslyra down the toilet or pour it into a drain unless instructed to do so.
  • Check with your pharmacist or healthcare provider on the proper disposal method for Phoslyra.

In case of emergency/overdose

• Emergency Assistance: In case of a suspected overdose or emergency, contact your local poison control center or emergency room immediately.
• Symptoms of Overdose: Overdose symptoms may include symptoms of hypercalcemia, such as nausea, vomiting, constipation, loss of appetite, increased thirst, increased urination, confusion, and fatigue.

What other information should I know?

• Regular Monitoring: Your healthcare provider may conduct regular blood tests to monitor calcium and phosphate levels and adjust the dosage of Phoslyra as needed.
• Medication Interactions: Inform your healthcare provider about all medications, supplements, and over-the-counter drugs you are taking, as interactions may occur.
• Dietary Instructions: Follow any dietary restrictions or recommendations provided by your healthcare provider to manage hyperphosphatemia effectively.
• Pregnancy and Breastfeeding: Discuss the potential risks and benefits of Phoslyra with your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding.
• Follow Healthcare Provider’s Advice: Always take Phoslyra exactly as prescribed by your healthcare provider. Do not adjust the dosage without consulting them.
• Allergic Reactions: Be aware of signs of an allergic reaction, such as rash, itching, swelling, severe dizziness, or difficulty breathing, and seek immediate medical attention if they occur.
• Regular Appointments: Attend regular follow-up appointments with your healthcare provider to monitor your response to Phoslyra and address any concerns or side effects.

It’s important to note that this information is general and may not cover all individual circumstances. Always consult with your healthcare provider or pharmacist for specific guidance related to your prescription of Phoslyra. If you have immediate concerns, contact your healthcare provider or local poison control center.