Why is this medication prescribed?

PhosLo is a brand name for calcium acetate, a medication commonly prescribed to control high levels of phosphate in the blood, a condition known as hyperphosphatemia. Hyperphosphatemia often occurs in individuals with chronic kidney disease (CKD) or end-stage renal disease (ESRD), as the kidneys are responsible for filtering and excreting excess phosphate from the body. When kidney function is impaired, phosphate levels can rise, leading to complications such as bone and mineral disorders.

PhosLo works by binding to dietary phosphate in the intestines, preventing its absorption and reducing the overall phosphate levels in the bloodstream. By controlling phosphate levels, PhosLo helps manage complications associated with hyperphosphatemia, such as bone problems and calcium deposits in soft tissues.

How should this medicine be used?

PhosLo (calcium acetate) is typically prescribed to control elevated levels of phosphate in the blood, particularly in individuals with chronic kidney disease (CKD) or end-stage renal disease (ESRD). It’s crucial to follow your healthcare provider’s instructions regarding the dosage and administration of PhosLo. The following general guidelines can provide an overview:

• Dosage: The dosage of PhosLo will be determined by your healthcare provider based on your specific condition, kidney function, and phosphate levels. Do not alter the dosage without consulting your healthcare professional.
• Administration: PhosLo is usually taken with meals or snacks. Taking it with food helps the medication bind to dietary phosphate, reducing its absorption in the intestines. This is important for individuals with impaired kidney function who may have difficulty excreting excess phosphate.
• Tablet Form: PhosLo is available in tablet form. Swallow the tablets whole with a glass of water. Do not crush or chew the tablets unless your healthcare provider specifically instructs you to do so.
• Consistency with Meals: Try to take PhosLo with each meal or snack consistently. This helps maintain a steady level of phosphate binding throughout the day.
• Regular Monitoring: Your healthcare provider may monitor your phosphate levels regularly through blood tests. This allows them to adjust the dosage if needed and ensure the medication is effectively controlling hyperphosphatemia.
• Other Medications: Inform your healthcare provider about all medications, supplements, and over-the-counter drugs you are taking, as certain medications may interact with PhosLo.
• Adherence to Prescribed Schedule: Follow the prescribed schedule provided by your healthcare provider. If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule.
• Potential Side Effects: Be aware of potential side effects and report any unusual symptoms or side effects to your healthcare provider promptly.

Always consult your healthcare provider for personalized advice regarding the use of PhosLo based on your specific medical condition and needs. If you have any questions or concerns about the medication, don’t hesitate to discuss them with your healthcare professional.

Other uses for this medicine

PhosLo (calcium acetate) is primarily prescribed for the management of hyperphosphatemia in individuals with chronic kidney disease (CKD) or end-stage renal disease (ESRD). However, there are no widely accepted alternative uses for PhosLo outside of this context. It’s crucial to use the medication only as prescribed by your healthcare provider and for the intended purpose.

What special precautions should I follow?

Special precautions should be taken when using PhosLo, and it’s essential to follow your healthcare provider’s guidance. Here are some general precautions:

• Kidney Function Monitoring: Regular monitoring of kidney function, including serum phosphate levels, is important. Your healthcare provider will adjust the dosage based on your specific needs.
• Calcium Levels: PhosLo contains calcium, and excessive intake of calcium may lead to hypercalcemia (high levels of calcium in the blood). Your healthcare provider will monitor your calcium levels and adjust the dosage accordingly.
• Interaction with Other Medications: Inform your healthcare provider about all medications, supplements, and over-the-counter drugs you are taking, as some medications may interact with PhosLo. In particular, avoid taking other calcium-containing supplements without your healthcare provider’s approval.
• Allergies: Inform your healthcare provider of any known allergies, especially if you have had an allergic reaction to calcium-containing medications or any other substances.
• Pregnancy and Breastfeeding: If you are pregnant, planning to become pregnant, or breastfeeding, discuss the risks and benefits of using PhosLo with your healthcare provider. The safety of PhosLo during pregnancy and breastfeeding has not been well studied, so it should only be used if the potential benefits outweigh the risks.
• Calcium-Containing Foods: Be mindful of your dietary intake of calcium-containing foods. Your healthcare provider may provide dietary guidelines to ensure a balance between managing phosphate levels and maintaining adequate calcium intake.
• Regular Follow-Up: Attend regular follow-up appointments with your healthcare provider to assess the effectiveness of the treatment, monitor for any side effects, and make any necessary adjustments to your medication regimen.

Always follow your healthcare provider’s recommendations and report any unusual symptoms or side effects promptly. If you have concerns or questions about PhosLo or your treatment plan, consult with your healthcare provider for personalized advice based on your specific health situation.

What special dietary instructions should I follow?

Special Dietary Instructions for PhosLo:

• Take with Meals: PhosLo is typically taken with meals or snacks. This helps the medication bind to dietary phosphate, reducing its absorption in the intestines.
• Consistent Timing: Try to take PhosLo with each meal consistently. Maintaining a regular schedule helps ensure a steady level of phosphate binding throughout the day.
• Calcium Intake: Be aware of your overall calcium intake, including dietary sources and supplements. Your healthcare provider may provide guidance on maintaining an appropriate balance.

What should I do if I forget a dose?

• Take as Soon as Possible: If you forget a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule.
• Do Not Double Dose: Do not take a double dose to make up for a missed one. Taking too much PhosLo at once can increase the risk of side effects.
• Consult Your Healthcare Provider: If you have questions about missed doses or concerns about your medication schedule, consult with your healthcare provider for guidance.

What side effects can this medication cause?

PhosLo (calcium acetate) may cause side effects, and it’s important to be aware of potential reactions. Common side effects are usually mild and may include:

• Upset Stomach: This can include nausea, vomiting, or stomach pain.
• Constipation: PhosLo may cause constipation, which can be managed with increased fluid intake and dietary fiber.
• Loss of Appetite: Some individuals may experience a decreased desire to eat.
• Dry Mouth: PhosLo can lead to a dry or metallic taste in the mouth.
• Increased Calcium Levels: Because PhosLo contains calcium, there is a potential for elevated calcium levels in the blood (hypercalcemia), especially if the medication is not taken as directed.

It’s important to note that serious side effects are rare but can occur. These may include:

• Signs of Hypercalcemia: These can include confusion, weakness, constipation, increased thirst or urination, and an irregular heartbeat. High calcium levels can be serious and require prompt medical attention.
• Allergic Reactions: In rare cases, individuals may experience an allergic reaction to PhosLo, which can include rash, itching, swelling, severe dizziness, or difficulty breathing.
• Symptoms of Overdose: Taking too much PhosLo can lead to an overdose of calcium, resulting in symptoms such as nausea, vomiting, weakness, confusion, and coma. Seek immediate medical attention if an overdose is suspected.

It’s essential to report any unusual or severe symptoms to your healthcare provider promptly. Additionally, inform your healthcare provider of any pre-existing medical conditions or medications you are taking, as certain conditions or drug interactions may increase the risk of side effects.

This list is not exhaustive, and individual responses to medication can vary. Always follow your healthcare provider’s instructions, attend regular check-ups, and communicate openly about any concerns or side effects you may be experiencing. If you have questions or encounter unexpected symptoms while taking PhosLo, seek medical advice promptly.

What should I know about storage and disposal of this medication?

Storage and Disposal of PhosLo:

• Storage:
  • Store PhosLo at room temperature away from moisture and heat.
  • Keep the medication in its original container with the lid tightly closed.
  • Avoid storing PhosLo in the bathroom.
• Disposal:
  • Follow local regulations for the disposal of unused or expired medications.
  • Do not flush PhosLo down the toilet unless instructed to do so.
  • Dispose of medications through drug take-back programs or community disposal programs when available.
  • If no take-back program is available, mix PhosLo with an unappealing substance (such as dirt or used coffee grounds) in a sealed plastic bag and discard it in the household trash.

In case of emergency/overdose

In case of an emergency or suspected overdose, seek immediate medical attention. Symptoms of an overdose may include nausea, vomiting, weakness, confusion, and coma. Call your local poison control center at 1-800-222-1222 or go to the nearest emergency room.

What other information should I know?

• Regular Monitoring: Attend regular follow-up appointments with your healthcare provider for monitoring of kidney function, phosphate levels, and any potential side effects.
• Dietary Considerations: Follow any dietary instructions provided by your healthcare provider. This may include restrictions on certain foods or supplements high in calcium or phosphate.
• Medical Alerts: Inform other healthcare providers, including dentists and emergency medical personnel, that you are taking PhosLo. This is important for avoiding potential interactions with other medications or treatments.
• Missed Doses: If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double dose.
• Pregnancy and Breastfeeding: If you are pregnant, planning to become pregnant, or breastfeeding, discuss the risks and benefits of using PhosLo with your healthcare provider.
• Allergies: If you have known allergies or hypersensitivities, inform your healthcare provider.
• Other Medications: Inform your healthcare provider about all medications, supplements, and over-the-counter drugs you are taking, as some medications may interact with PhosLo.

Always follow the specific instructions provided by your healthcare provider and the medication packaging. If you have any questions or concerns, consult with your healthcare provider or pharmacist for clarification.