Why is this medication prescribed?

Teriparatide is a medication used to treat osteoporosis in postmenopausal women and men who are at high risk of fractures. Osteoporosis is a condition characterized by weakened bones, making them more susceptible to fractures.

Teriparatide is a form of parathyroid hormone (PTH) that helps to increase bone density and reduce the risk of fractures. It stimulates the formation of new bone and improves bone mass and strength.

How should this medicine be used?

Here are some general guidelines for using Teriparatide Injection:

• Dosage: The typical dose is a once-daily injection under the skin (subcutaneous injection). The injection is usually given in the thigh or abdominal wall.
• Timing: It’s essential to take the medication at the same time each day.
• Administration: The injection is typically self-administered by the patient. Your healthcare provider will provide instructions on how to properly administer the injection. It’s important to follow these instructions carefully.
• Storage: Teriparatide should be stored in the refrigerator, and each prefilled pen or cartridge should be used within 28 days after the first injection.
• Follow-up: Regular follow-up appointments with your healthcare provider are necessary to monitor the effectiveness of the medication and address any potential side effects.

It’s crucial to note that the information provided here is general, and individual cases may vary. Always follow the specific instructions provided by your healthcare provider and read the medication guide that comes with the prescription. If you have any questions or concerns about the use of Teriparatide or its potential side effects, consult with your healthcare professional.

Other uses for this medicine

Teriparatide is primarily prescribed for the treatment of osteoporosis. However, healthcare providers may sometimes consider its use for conditions not mentioned in the official prescribing information. Such off-label uses are determined based on the individual patient’s needs and the healthcare provider’s judgment.

What special precautions should I follow?

As for special precautions when using Teriparatide Injection, consider the following:

• Medical History: Inform your healthcare provider about your complete medical history, especially if you have a history of bone cancer, high levels of calcium in the blood, or metabolic bone disorders other than osteoporosis.
• Pregnancy and Breastfeeding: Teriparatide is generally not recommended during pregnancy or breastfeeding unless the potential benefits outweigh the risks. Consult with your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding.
• Allergies: Inform your healthcare provider about any allergies you may have, especially if you are allergic to any ingredients in Teriparatide.
• Calcium and Vitamin D Supplements: Your healthcare provider may recommend calcium and vitamin D supplements while you are on Teriparatide to support bone health.
• Kidney Function: If you have kidney problems, your healthcare provider may need to adjust the dosage of Teriparatide accordingly.
• Orthostatic Hypotension: Teriparatide may cause a drop in blood pressure, especially when standing up. If you experience dizziness or lightheadedness, it’s important to rise slowly from a sitting or lying position.
• Bone Cancer Risk: There is a theoretical risk of osteosarcoma, a rare type of bone cancer, associated with the use of Teriparatide. It’s important to discuss this risk with your healthcare provider.
• Monitoring: Regular monitoring of bone density and other relevant parameters may be required during the course of treatment.

Always follow your healthcare provider’s instructions and inform them about any medications, supplements, or medical conditions you may have before starting Teriparatide. If you experience any unusual or severe side effects, contact your healthcare provider promptly.

What special dietary instructions should I follow?

Regarding special dietary instructions for Teriparatide Injection, there aren’t specific dietary restrictions outlined in the prescribing information. However, maintaining a balanced and healthy diet that includes an adequate intake of calcium and vitamin D is generally recommended for overall bone health. Your healthcare provider may also recommend calcium and vitamin D supplements if needed.

What should I do if I forget a dose?

If you forget a dose of Teriparatide, take the missed dose as soon as you remember. However, if it’s almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double up on doses to make up for a missed one. If you are unsure about what to do, contact your healthcare provider or pharmacist for guidance.

What side effects can this medication cause?

Teriparatide Injection, like any medication, may cause side effects. It’s important to be aware of potential side effects and to promptly report any unusual or severe reactions to your healthcare provider. Common side effects of Teriparatide may include:

• Nausea
• Dizziness
• Leg cramps
• Injection site reactions (pain, redness, swelling, or bruising)

Less common but more serious side effects may include:

• Increased calcium levels in the blood (hypercalcemia): This can lead to symptoms such as nausea, vomiting, constipation, increased thirst, and confusion.
• Bone pain or pain in the joints, muscles, or legs: This may be a sign of increased calcium levels in the blood or may be related to the medication’s effect on bone turnover.
• Orthostatic hypotension: A drop in blood pressure upon standing, which may cause dizziness or lightheadedness.
• Osteosarcoma: While the risk is uncertain and primarily based on animal studies, there is a theoretical risk of developing osteosarcoma, a rare type of bone cancer, with the use of Teriparatide.

It’s important to note that the above lists are not exhaustive, and individual responses to medication can vary. Additionally, this information may not include the most up-to-date list of side effects. Always consult the prescribing information provided with the medication or speak with your healthcare provider for the most accurate and current information.

If you experience any severe or persistent side effects, contact your healthcare provider promptly. They can help assess whether any adjustments to your treatment plan are necessary. In case of a medical emergency or severe reaction, seek immediate medical attention.

What should I know about storage and disposal of this medication?

Here’s important information regarding the storage and disposal for Teriparatide Injection:

Storage:

• Refrigeration: Teriparatide should be stored in the refrigerator between 36°F to 46°F (2°C to 8°C). Do not freeze.
• Protect from Light: Keep the Teriparatide Injection away from light.
• Unused Pens/Cartridges: If you have unused pens or cartridges, keep them in the refrigerator.
• In-Use Pens/Cartridges: Once in use, Teriparatide pens or cartridges can be kept at room temperature (up to 77°F or 25°C) for up to 28 days.

Disposal:

• Needle Disposal: Safely dispose of needles and syringes in an appropriate sharps container. Do not throw them in the regular trash.
• Unused Medication: Follow specific instructions from your healthcare provider or pharmacist on how to dispose of any unused Teriparatide medication.

In case of emergency/overdose

• Contact Healthcare Provider: If you suspect an overdose or experience severe side effects, contact your healthcare provider or seek medical attention immediately.
• Symptoms of Overdose: Overdose symptoms may include nausea, vomiting, dizziness, weakness, and confusion.

What other information should I know?

• Regular Monitoring: Your healthcare provider may conduct regular tests to monitor your response to Teriparatide, including bone density tests and blood calcium levels.
• Follow-Up Appointments: Attend all follow-up appointments with your healthcare provider as scheduled.
• Inform Healthcare Provider: Keep your healthcare provider informed about all medications you are taking, including prescription and over-the-counter drugs, as well as any supplements.
• Medical Alert Bracelet: If you have a medical condition that may affect emergency treatment, consider wearing a medical alert bracelet or carrying an identification card.

Always follow your healthcare provider’s instructions and read the medication guide provided with Teriparatide for detailed and specific information. If you have any questions or concerns, consult your healthcare provider or pharmacist for guidance.