Why is this medication prescribed?

Pancreaze is a prescription medication used to help people with conditions that result in a lack of digestive enzymes, such as pancreatic insufficiency. Pancreatic insufficiency can occur in individuals with cystic fibrosis, chronic pancreatitis, or other conditions that affect the pancreas. In these cases, the body may not produce enough digestive enzymes to properly break down and absorb nutrients from food.

Pancreaze contains a combination of enzymes, including lipase, protease, and amylase, which help digest fats, proteins, and carbohydrates, respectively. By providing these enzymes in supplement form, Pancreaze helps support the digestion and absorption of nutrients in the digestive system.

How should this medicine be used?

The dosage of Pancreaze is individualized based on the patient’s specific needs, and it should be determined by the healthcare provider. Generally, the medication is taken with meals and snacks, and the dosage may be adjusted based on the patient’s response and dietary habits.

Here are some general guidelines for using Pancreaze:

• Dosage: Follow the dosage instructions provided by your healthcare provider. Do not alter the dosage without consulting your doctor.
• Administration: Pancreaze should be taken with meals and snacks. The capsules can be swallowed whole or opened and sprinkled on a small amount of acidic soft food (such as applesauce) just before ingestion. The mixture should be swallowed immediately without chewing.
• Timing: Take Pancreaze as directed by your healthcare provider, usually with every meal and snack. If a meal is skipped or a snack is small, the medication may not be needed or the dosage may be adjusted.
• Monitoring: Your healthcare provider may periodically adjust your dosage based on your response, changes in diet, or other factors affecting your pancreatic enzyme needs.
• Storage: Store Pancreaze at room temperature and protect it from moisture.

It’s crucial to communicate with your healthcare provider about any concerns, side effects, or changes in your condition. They will be able to provide guidance on the proper use of Pancreaze based on your specific medical history and needs. Always take prescription medications exactly as prescribed to ensure optimal effectiveness and safety.

Other uses for this medicine

Pancreaze is primarily indicated for the treatment of exocrine pancreatic insufficiency associated with cystic fibrosis or other conditions. It is not recommended for other uses unless specifically prescribed by a healthcare professional.

What special precautions should I follow?

Special precautions should be taken when using Pancreaze, and it is essential to follow your healthcare provider’s guidance. Here are some important precautions to consider:

• Allergies: Inform your healthcare provider about any allergies you may have, especially if you are allergic to pork (as Pancreaze is derived from porcine pancreatic tissue).
• Medical Conditions: Inform your doctor about any existing medical conditions or a history of gastrointestinal obstructions or bleeding disorders.
• Pregnancy and Breastfeeding: If you are pregnant, planning to become pregnant, or breastfeeding, discuss the risks and benefits of using Pancreaze with your healthcare provider.
• Other Medications: Inform your healthcare provider about all the medications, including prescription and over-the-counter drugs, as well as dietary supplements, that you are currently taking. Some medications may interact with Pancreaze.
• Dosage Adjustments: Your healthcare provider may need to adjust the dosage of Pancreaze based on your individual needs, changes in your condition, or alterations in your diet.
• Monitoring: Regularly follow up with your healthcare provider for monitoring and adjustments to your treatment plan. Periodic assessments of your response to Pancreaze and any potential side effects are important.
• Side Effects: Be aware of potential side effects, including allergic reactions, abdominal pain, bloating, diarrhea, constipation, and changes in blood sugar levels. If you experience severe or persistent side effects, contact your healthcare provider.
• Storage: Store Pancreaze in a cool, dry place and follow the recommended storage instructions on the medication packaging.

Always take Pancreaze exactly as prescribed by your healthcare provider. If you have any questions or concerns about the medication, do not hesitate to reach out to your healthcare team for clarification. It’s crucial to maintain open communication with your healthcare provider to ensure the safe and effective use of Pancreaze based on your individual health needs.

What special dietary instructions should I follow?

• Take with Meals and Snacks: Pancreaze is typically taken with meals and snacks to aid in the digestion of fats, proteins, and carbohydrates.
• Follow Dietary Advice: Your healthcare provider may provide specific dietary advice or restrictions. Follow their recommendations to optimize the effectiveness of Pancreaze.

What should I do if I forget a dose?

If you forget to take a dose of Pancreaze:

• If it’s close to the next dose: If you realize you missed a dose and it’s almost time for your next scheduled dose, skip the missed dose. Do not double up on doses to make up for a missed one.
• If it’s not close to the next dose: Take the missed dose as soon as you remember. If it’s almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.
• Do not double dose: Do not take extra doses to make up for a missed one. Taking more than the prescribed amount can lead to side effects and complications.

What side effects can this medication cause?

Pancreaze, like any medication, may cause side effects in some individuals. It’s important to note that not everyone will experience these side effects, and some people may experience side effects that are not listed. If you are prescribed Pancreaze and have concerns about potential side effects, it’s crucial to discuss them with your healthcare provider. Common side effects of Pancreaze may include:

• Gastrointestinal Disturbances: This can include abdominal pain, bloating, gas, and diarrhea. Adjustments to the dosage or changes in diet may help alleviate these symptoms.
• Constipation: Some individuals may experience constipation as a side effect.
• Changes in Blood Sugar Levels: Pancreatic enzyme replacement therapy, including Pancreaze, may affect blood sugar levels. People with diabetes may need adjustments to their diabetes management plan.
• Allergic Reactions: While rare, allergic reactions may occur. Seek medical attention if you experience symptoms such as rash, itching, swelling, severe dizziness, or difficulty breathing.
• High Blood Uric Acid Levels: This can lead to gout in some individuals.
• Elevated Liver Enzymes: Pancreaze may cause an increase in liver enzymes in some cases.
• Fibrosing Colonopathy: Long-term, high-dose use of pancreatic enzyme replacement products has been associated with a condition called fibrosing colonopathy, characterized by thickening of the colon walls. This is rare but has been reported, particularly in children.

It’s important to report any unusual or severe side effects to your healthcare provider promptly. Additionally, adherence to the prescribed dosage and regular follow-up appointments with your healthcare provider can help monitor for potential side effects and adjust the treatment plan if needed.

This is not an exhaustive list of side effects, and individual responses to medication can vary. Always consult with your healthcare provider or pharmacist for more comprehensive information about potential side effects associated with Pancreaze, and seek medical attention if you experience any concerning symptoms.

What should I know about storage and disposal of this medication?

Storage and Disposal of Pancreaze:

• Storage:
  • Store Pancreaze at room temperature, away from moisture and heat.
  • Do not store the medication in the bathroom.
  • Keep it out of reach of children and pets.
• Disposal:
  • Follow local guidelines for medication disposal. Do not flush Pancreaze down the toilet unless specifically instructed to do so.
  • Check with your pharmacist or healthcare provider on the proper disposal method. Some communities have specific medication disposal programs or facilities.

In case of emergency/overdose

• In case of an overdose or emergency, contact your local poison control center at 1-800-222-1222 or seek emergency medical attention immediately.
• Symptoms of overdose may include severe abdominal pain, persistent constipation, and other gastrointestinal symptoms. Do not ignore any signs of potential overdose.

What other information should I know?

• Regular Follow-up: Attend regular follow-up appointments with your healthcare provider to monitor your response to Pancreaze and make any necessary adjustments to your treatment plan.
• Communication: Keep an open line of communication with your healthcare provider. Report any new symptoms, changes in your condition, or concerns about the medication promptly.
• Dietary Considerations: Follow any dietary instructions provided by your healthcare provider. Proper dietary management is often crucial for optimizing the effectiveness of Pancreaze.
• Other Medications: Inform your healthcare provider about all medications, including prescription and over-the-counter drugs, as well as dietary supplements, that you are taking. Some medications may interact with Pancreaze.
• Allergies: If you are allergic to pork, inform your healthcare provider, as Pancreaze is derived from porcine pancreatic tissue.
• Pregnancy and Breastfeeding: If you are pregnant, planning to become pregnant, or breastfeeding, discuss the risks and benefits of using Pancreaze with your healthcare provider.
• Travel: If you are traveling, ensure you have an adequate supply of Pancreaze. Consult with your healthcare provider before traveling to discuss any adjustments to your treatment plan.
• Monitoring Blood Sugar: If you have diabetes, monitor your blood sugar levels closely, as Pancreaze may affect blood sugar.

Always follow your healthcare provider’s instructions and seek their guidance for any specific concerns or questions you may have about Pancreaze. If you experience any unexpected or severe side effects, contact your healthcare provider promptly.