WARNING

Orudis is a nonsteroidal anti-inflammatory drug (NSAID) that contains the active ingredient ketoprofen. While it can be effective in treating pain, inflammation, and fever, it is important to be aware of the potential risks associated with its use. Here are some of the risks of taking Orudis:

• Gastrointestinal issues: Orudis can cause gastrointestinal problems such as stomach ulcers, bleeding, and perforation. These risks are higher in individuals with a history of stomach ulcers, digestive disorders, or those who take higher doses or use it for a prolonged period.
• Cardiovascular complications: NSAIDs, including Orudis, may increase the risk of cardiovascular events such as heart attack or stroke, especially when used in high doses or for long durations. This risk may be higher in individuals with pre-existing heart conditions or those with multiple cardiovascular risk factors.
• Kidney problems: Orudis can potentially cause or worsen kidney problems, including acute kidney injury or kidney failure. Individuals with existing kidney conditions, dehydration, or those taking other medications that affect the kidneys are at a higher risk.
• Allergic reactions: Some individuals may experience allergic reactions to Orudis, which can range from mild symptoms like rash and itching to severe reactions such as difficulty breathing, swelling, or anaphylaxis. It is important to seek immediate medical attention if any signs of an allergic reaction occur.
• Other side effects: Common side effects of Orudis include stomach pain, indigestion, nausea, dizziness, headache, and fluid retention. It can also interact with other medications, so it’s essential to inform your healthcare provider about all the medications you are taking.

It is crucial to use Orudis as directed by a healthcare professional and to discuss any concerns or pre-existing medical conditions before starting the medication. Regular monitoring and follow-up with your healthcare provider are important to minimize the risks and ensure its safe use.

Why is this medication prescribed?

Orudis, which contains the active ingredient ketoprofen, is a nonsteroidal anti-inflammatory drug (NSAID) that is primarily prescribed to relieve pain, reduce inflammation, and lower fever. Here are some common conditions for which Orudis may be prescribed:

• Pain relief: Orudis can be used to alleviate mild to moderate pain, such as headaches, dental pain, menstrual cramps, muscle aches, and joint pain caused by conditions like arthritis or gout.
• Inflammation reduction: It is often prescribed to reduce inflammation associated with conditions like rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, and other inflammatory joint diseases.
• Fever reduction: Orudis can help lower fever associated with various infections or illnesses.

How should this medicine be used?

When using Orudis, it is important to follow the prescribed dosage and instructions provided by your healthcare professional. Here are some general guidelines:

• Dosage: The recommended dosage of Orudis will vary depending on the condition being treated and individual factors. It is typically taken two or three times a day, with or without food. The dosage and duration of treatment should be determined by your healthcare provider.
• Duration of use: Orudis is usually prescribed for short-term use to manage acute pain or inflammation. Prolonged or excessive use can increase the risk of side effects, so it is important to use it only as directed and for the prescribed duration.
• Swallowing the tablets: Orudis tablets should be swallowed whole with a glass of water. It is important not to crush, chew, or break the tablets unless instructed otherwise by your healthcare provider.
• Regular follow-up: Regular check-ups with your healthcare provider are recommended to monitor your response to the medication, assess any side effects, and make any necessary adjustments to your treatment plan.

Remember to always consult your healthcare provider for specific instructions on how to use Orudis, as they will consider your medical history, individual needs, and potential interactions with other medications you may be taking.

Other uses for this medicine

It is important to note that Orudis should be used under the guidance of a healthcare professional. The dosage and duration of use will vary depending on the individual and the specific condition being treated. It is typically taken orally, with or without food, and should be swallowed whole with a full glass of water to minimize the risk of stomach upset. It is important to follow the instructions provided by the prescribing physician or the medication’s label.

What special precautions should I follow?

Orudis should be used strictly as prescribed by a healthcare professional, and it’s crucial to follow the recommended dosage and duration of treatment. Like any medication, Orudis has potential side effects and precautions to consider. Here are some special precautions associated with Orudis:

• Allergic reactions: Individuals with known hypersensitivity to ketoprofen or other NSAIDs should avoid using Orudis, as it can cause severe allergic reactions.
• Gastrointestinal risks: Orudis may increase the risk of gastrointestinal ulcers, bleeding, and perforation, which can be serious or even life-threatening. It’s important to inform your healthcare provider if you have a history of stomach ulcers, gastrointestinal bleeding, or other digestive system disorders.
• Cardiovascular effects: NSAIDs, including Orudis, have been associated with an increased risk of cardiovascular events such as heart attack and stroke, especially when used in high doses or for prolonged periods. Individuals with existing cardiovascular conditions should exercise caution and discuss the risks with their healthcare provider.
• Kidney function: Orudis can affect kidney function and may cause fluid retention, particularly in individuals with pre-existing kidney problems or reduced kidney function. Regular monitoring of kidney function may be necessary during treatment.
• Other medications and conditions: Orudis may interact with certain medications or medical conditions. Inform your healthcare provider about all the medications you are taking, including over-the-counter drugs and supplements, as well as any underlying health conditions you have, to avoid potential interactions or complications.

Always consult with your healthcare provider or pharmacist for specific guidance regarding the use of Orudis, as they can provide personalized advice based on your individual medical history and needs.

What special dietary instructions should I follow?

When taking Orudis (ketoprofen), there are no specific dietary restrictions that need to be followed. However, it’s generally advisable to take the medication with food or milk to help minimize the risk of gastrointestinal side effects, such as stomach upset or ulcers. Taking Orudis on an empty stomach may increase the likelihood of these adverse effects.

What should I do if I forget a dose?

If you forget to take a dose of Orudis, you should take it as soon as you remember. However, if it is close to the time for your next scheduled dose, it is generally recommended to skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one. Taking more than the prescribed amount can increase the risk of side effects.

What side effects can this medication cause?

Orudis (ketoprofen) can potentially cause several side effects, although not everyone who takes the medication will experience them. Common side effects of Orudis may include:

• Gastrointestinal effects: These can include stomach pain, indigestion, heartburn, nausea, vomiting, diarrhea, and loss of appetite. In some cases, Orudis can cause more serious gastrointestinal problems such as gastrointestinal ulcers, bleeding, and perforation, which may require immediate medical attention.
• Cardiovascular effects: NSAIDs like Orudis have been associated with an increased risk of cardiovascular events, including heart attack and stroke, particularly when used in high doses or for long durations.
• Kidney problems: Orudis may affect kidney function and can lead to fluid retention or kidney damage, especially in individuals with pre-existing kidney problems.
• Allergic reactions: Some people may experience allergic reactions to Orudis, which can manifest as hives, rash, itching, swelling, difficulty breathing, or a severe skin reaction known as Stevens-Johnson syndrome.
• Central nervous system effects: These can include dizziness, headache, drowsiness, and in rare cases, nervousness, confusion, or hallucinations.
• Skin reactions: Orudis can sometimes cause photosensitivity (increased sensitivity to sunlight), resulting in a higher risk of sunburn. Skin reactions such as dermatitis and eczema have also been reported.
• Blood disorders: Rarely, Orudis may affect blood cells, leading to conditions such as anemia, decreased platelet count, or decreased white blood cell count.

It’s important to note that this is not an exhaustive list of side effects, and other reactions may occur. If you experience any unusual or severe side effects while taking Orudis, it is important to seek medical attention promptly.

Additionally, it’s crucial to discuss any concerns or potential risks with your healthcare provider before starting Orudis or any other medication. They can provide you with personalized advice based on your medical history and help monitor for any adverse effects during your treatment.

What should I know about storage and disposal of this medication?

• Storage: Store Orudis at room temperature, away from moisture, heat, and direct light. Follow any specific storage instructions provided on the medication’s packaging or as advised by your pharmacist.
• Disposal: Properly dispose of unused or expired Orudis. Do not flush it down the toilet or pour it into drains unless instructed to do so. Consult your local regulations or community guidelines on the proper disposal of medications. You can often take unused medications to a local pharmacy or follow specific guidelines provided by your healthcare provider or local waste management authorities.

In case of emergency/overdose

In case of an emergency or suspected overdose, call your local emergency services (such as 911) or go to the nearest emergency room immediately. It is helpful to have the medication bottle or packaging with you to provide essential information to healthcare professionals. Overdose symptoms may include severe stomach pain, vomiting blood, black or bloody stools, difficulty breathing, dizziness, fainting, or seizures.

What other information should I know?

• Inform your healthcare provider about all medications you are taking, including over-the-counter drugs, supplements, and herbal remedies, as they may interact with Orudis.
• Avoid using Orudis alongside other NSAIDs or corticosteroids unless specifically directed by your healthcare provider, as it may increase the risk of adverse effects.
• Discuss your medical history, including any allergies, asthma, stomach ulcers, bleeding disorders, liver or kidney problems, or heart conditions, with your healthcare provider before starting Orudis.
• Inform healthcare professionals, including dentists or surgeons, that you are taking Orudis before any scheduled procedures or surgeries.
• Regularly monitor for signs of gastrointestinal bleeding, such as stomach pain, bloody or black stools, or vomiting blood, and seek medical attention if these symptoms occur.
• Keep all appointments with your healthcare provider for check-ups and monitoring while taking Orudis.
• Do not exceed the prescribed dosage or duration of treatment unless advised by your healthcare provider.

It is essential to follow your healthcare provider’s instructions and ask any specific questions you may have about Orudis or your treatment plan. They are best equipped to provide personalized advice based on your individual needs and medical history.