Why is this medication prescribed?
Nexletol (generic name: bempedoic acid) is prescribed to help lower LDL cholesterol levels in adults with primary hyperlipidemia or mixed dyslipidemia. LDL cholesterol, often referred to as “bad” cholesterol, is a type of cholesterol that can contribute to the development of cardiovascular diseases such as heart attacks and strokes.
Nexletol is typically used in combination with a statin medication and a healthy diet to further lower LDL cholesterol levels when statins alone are not sufficient or are not tolerated well by the patient. It belongs to a class of medications known as ATP citrate lyase inhibitors, which work by reducing the production of cholesterol in the liver.
How should this medicine be used?
The usual recommended dose of Nexletol is 180 mg once daily, taken orally with or without food. It can be taken at any time of the day, but it is important to take it consistently at the same time each day. It is important to follow the dosage instructions provided by your healthcare provider and not exceed the prescribed dose.
If you have been prescribed Nexletol, it is important to continue following a healthy diet and exercise routine as advised by your doctor. Regular monitoring of cholesterol levels and liver function may also be recommended during treatment with Nexletol. As always, it is essential to consult with your healthcare provider for personalized advice and guidance regarding the use of this medication.
Other uses for this medicine
Nexletol (bempedoic acid) is primarily prescribed for the treatment of high LDL cholesterol levels. However, it is important to note that medications are typically prescribed for specific approved indications. The approved use of Nexletol is limited to lowering LDL cholesterol in patients with primary hyperlipidemia or mixed dyslipidemia.
What special precautions should I follow?
Regarding special precautions, it is crucial to consider the following:
- Allergies: If you are allergic to bempedoic acid or any of the other ingredients in Nexletol, you should not take this medication.
- Liver function: Nexletol may have an impact on liver function. Before starting Nexletol, your healthcare provider may assess your liver function and periodically monitor it during treatment. If you have a history of liver disease or experience symptoms such as unexplained fatigue, loss of appetite, yellowing of the skin or eyes (jaundice), or dark urine, you should inform your doctor promptly.
- Muscle-related side effects: Like other cholesterol-lowering medications, Nexletol may have the potential to cause muscle-related side effects, such as muscle pain, tenderness, or weakness. If you experience any unusual muscle symptoms, it is important to inform your healthcare provider.
- Drug interactions: Nexletol may interact with other medications, including certain statins and fibrates. It is important to inform your doctor about all the medications, supplements, or herbal products you are taking to avoid potential drug interactions.
- Pregnancy and breastfeeding: The safety of Nexletol during pregnancy and breastfeeding has not been established. If you are pregnant, planning to become pregnant, or breastfeeding, you should discuss the potential risks and benefits of Nexletol with your healthcare provider.
These precautions are not exhaustive, and it is crucial to consult with your healthcare provider or pharmacist for comprehensive information and guidance specific to your situation.
What special dietary instructions should I follow?
When taking Nexletol (bempedoic acid), there are no specific dietary restrictions or instructions that need to be followed. However, it is generally recommended to maintain a healthy diet as advised by your healthcare provider. This includes consuming a balanced diet low in saturated fats and cholesterol, and rich in fruits, vegetables, whole grains, and lean proteins.
What should I do if I forget a dose?
If you happen to miss a dose of Nexletol, you should take it as soon as you remember. However, if it is close to the time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. It is important not to take a double dose to make up for the missed one.
What side effects can this medication cause?
Nexletol (bempedoic acid) may cause side effects in some individuals. The most commonly reported side effects include:
- Muscle-related symptoms: Muscle pain, muscle spasms, or muscle weakness are the most commonly reported side effects. If you experience persistent or severe muscle pain, tenderness, or weakness, it is important to inform your healthcare provider.
- Upper respiratory tract infection: Symptoms such as sore throat, runny nose, cough, and congestion have been reported by some individuals taking Nexletol.
- Back pain: Some people may experience back pain as a side effect of Nexletol.
- Abdominal pain: Abdominal pain or discomfort, including stomach ache, may occur.
- Pain in extremities: Some individuals may experience pain or discomfort in their arms, legs, hands, or feet.
- Increased uric acid levels: Nexletol may cause an increase in uric acid levels in some individuals. This could lead to gout or exacerbate existing gout symptoms.
It’s important to note that not everyone will experience these side effects, and some people may experience different or no side effects at all. If you have any concerns about the side effects of Nexletol or if you experience any unexpected symptoms while taking the medication, it is recommended to consult your healthcare provider for further evaluation and guidance. They can provide appropriate advice based on your specific situation.
What should I know about storage and disposal of this medication?
- Storage: Store Nexletol at room temperature, away from excessive heat, moisture, and direct light. Follow the specific storage instructions provided by the manufacturer or on the medication packaging.
- Disposal: It is important to dispose of Nexletol properly and safely to prevent accidental ingestion by others. You can check with your local pharmacy or healthcare provider for guidance on proper medication disposal methods in your area. Do not flush Nexletol down the toilet or throw it in the trash unless specifically instructed to do so.
In case of emergency/overdose
- Emergency assistance: If you believe you or someone else may be experiencing a medical emergency or overdose, immediately call your local emergency services or go to the nearest emergency room.
- Overdose symptoms: Symptoms of an overdose may include severe muscle pain, muscle weakness, or other severe side effects. It is important to seek immediate medical attention if you suspect an overdose.
What other information should I know?
- Compliance: It is important to take Nexletol as prescribed by your healthcare provider. Do not exceed the recommended dose or change your dosage without consulting your doctor.
- Regular check-ups: Your doctor may periodically monitor your cholesterol levels and liver function during treatment with Nexletol. It is important to attend all scheduled appointments and inform your healthcare provider of any concerning symptoms or side effects.
- Drug interactions: Inform your healthcare provider about all the medications, supplements, or herbal products you are taking to avoid potential drug interactions with Nexletol.
- Effectiveness: Nexletol is part of a comprehensive treatment plan for managing cholesterol levels. It should be used in conjunction with a healthy diet, regular exercise, and other cholesterol-lowering medications as prescribed by your doctor.
Remember, this information is not exhaustive, and it is essential to consult with your healthcare provider or pharmacist for complete and personalized guidance regarding the storage, disposal, emergency procedures, and any other specific information related to your use of Nexletol.