Why is this medication prescribed?

Juluca is a prescription medication that is used for the treatment of human immunodeficiency virus type 1 (HIV-1) infection in adults who have already achieved viral suppression on a stable antiretroviral regimen. It is specifically indicated for individuals who have not experienced treatment failure in the past and do not have known or suspected resistance to the medications contained in Juluca.

Juluca is a fixed-dose combination medication that contains two active ingredients: dolutegravir and rilpivirine. These drugs belong to a class of antiretroviral medications known as integrase strand transfer inhibitors (dolutegravir) and non-nucleoside reverse transcriptase inhibitors (rilpivirine). When taken together, they work to suppress the replication of the HIV-1 virus and reduce its ability to multiply in the body.

How should this medicine be used?

Juluca is a fixed-dose combination medication that contains two active ingredients: dolutegravir and rilpivirine. Here is a general guideline on how Juluca should be used:

• Follow your healthcare provider’s instructions: It is important to follow the dosing instructions provided by your healthcare provider. They will prescribe the appropriate dose and frequency based on your individual needs and medical condition.
• Take Juluca with food: Juluca should be taken orally once daily with a meal. Taking the medication with food helps with its absorption and can reduce the risk of stomach upset.
• Take Juluca at the same time each day: To ensure consistent drug levels in your body, it is recommended to take Juluca at the same time every day. Choose a time that is convenient for you and set a reminder if needed.
• Swallow the tablet whole: Do not crush, chew, or break the tablet. Swallow it whole with water or another liquid.
• Do not miss doses: It is important to take Juluca every day as prescribed by your healthcare provider. If you accidentally miss a dose, take it as soon as you remember. However, if it is close to the time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.
• Avoid certain medications and supplements: Juluca may interact with other medications and supplements, so it is important to inform your healthcare provider about all the medications you are taking. Some drugs, such as certain antacids or laxatives, should be avoided or taken at a different time than Juluca to prevent interactions.
• Regularly monitor your HIV status: While taking Juluca, it is important to continue monitoring your HIV status and regularly visit your healthcare provider for check-ups, laboratory tests, and viral load monitoring.

It is crucial to remember that the information provided here is a general guideline. Always follow the specific instructions given by your healthcare provider and refer to the package insert or medication guide provided with Juluca for detailed instructions and precautions.

Other uses for this medicine

Juluca is a prescription medication that contains two active ingredients, dolutegravir and rilpivirine. It is primarily used for the treatment of human immunodeficiency virus type 1 (HIV-1) infection in adults who have already achieved viral suppression and are stable on their current antiretroviral regimen. Juluca is specifically indicated for individuals who have no history of treatment failure or resistance to the individual components of the medication.

What special precautions should I follow?

As for special precautions, it is crucial to follow your healthcare provider’s instructions and guidance while taking Juluca. Here are some general precautions to consider:

• Adherence: It is important to take Juluca exactly as prescribed, without missing any doses. Skipping doses or not following the prescribed regimen can lead to reduced effectiveness and the development of drug resistance.
• Other Medications: Inform your healthcare provider about all the medications you are taking, including prescription drugs, over-the-counter medications, and any herbal supplements. Certain medications may interact with Juluca, potentially affecting its efficacy or increasing the risk of side effects.
• Allergies: Notify your doctor if you have any known allergies or hypersensitivity to dolutegravir, rilpivirine, or any other ingredients in Juluca. Allergic reactions can be serious and require immediate medical attention.
• Pre-existing Conditions: Inform your healthcare provider about any pre-existing medical conditions, including liver or kidney problems, mental health conditions, or any other significant health issues. Your doctor will consider these factors when prescribing Juluca.
• Pregnancy and Breastfeeding: If you are pregnant, planning to become pregnant, or breastfeeding, discuss the potential risks and benefits of Juluca with your healthcare provider. They will evaluate whether it is safe for you and your baby.
• Side Effects: Be aware of the potential side effects of Juluca, which can include headache, dizziness, insomnia, depression, nausea, diarrhea, and rash. If you experience any concerning or persistent side effects, contact your healthcare provider.

Always consult with your healthcare provider or pharmacist for specific instructions and guidance on using Juluca, as they will have the most accurate and up-to-date information based on your individual circumstances.

What special dietary instructions should I follow?

Regarding dietary instructions for Jalyn, here are some general recommendations:

• Take Jalyn with or without food: You can take Jalyn with or without food, as it does not specifically require a meal for absorption. However, it is important to take it consistently the same way, either with food or without, to maintain consistent blood levels of the medication.
• Avoid grapefruit and grapefruit juice: Grapefruit and grapefruit juice may interact with certain medications, including tamsulosin. It can increase the levels of the drug in your blood and potentially lead to adverse effects. Therefore, it is generally recommended to avoid consuming grapefruit or its juice while taking Jalyn.
• Stay hydrated: It’s important to maintain good hydration while taking Jalyn, as dehydration can potentially worsen certain side effects of the medication, such as dizziness or lightheadedness.

What should I do if I forget a dose?

Regarding a missed dose of Jalyn, it is generally advised to take the missed dose as soon as you remember. However, if it is close to the time for your next scheduled dose, it is best to skip the missed dose and continue with your regular dosing schedule. It is important not to double the dose to make up for a missed one, as this can increase the risk of side effects.

What side effects can this medication cause?

Jalyn is a medication that combines two active ingredients: dutasteride and tamsulosin. It is primarily prescribed for the treatment of benign prostatic hyperplasia (BPH) in men. Like any medication, Jalyn can potentially cause side effects. Some of the common side effects associated with Jalyn include:

• Sexual side effects: Both dutasteride and tamsulosin can cause changes in sexual function. These may include decreased libido (sex drive), difficulty achieving or maintaining an erection, and reduced semen volume. These effects are usually reversible upon discontinuation of the medication.
• Dizziness or lightheadedness: Tamsulosin, one of the components of Jalyn, can cause a drop in blood pressure, leading to dizziness or lightheadedness, especially when going from a lying or sitting position to standing up quickly.
• Headache: Headaches are a common side effect of Jalyn and can range from mild to severe.
• Fatigue or drowsiness: Some individuals may experience feelings of tiredness or drowsiness while taking Jalyn.
• Gastrointestinal symptoms: Jalyn can cause gastrointestinal side effects such as nausea, vomiting, diarrhea, or constipation.
• Breast enlargement or tenderness: Dutasteride, the other component of Jalyn, can lead to breast enlargement or tenderness in some individuals.
• Allergic reactions: Although rare, allergic reactions to Jalyn can occur. Signs of an allergic reaction may include rash, itching, swelling (especially of the face, tongue, or throat), severe dizziness, or difficulty breathing.

It’s important to note that not everyone will experience these side effects, and the severity and occurrence can vary from person to person. If you are taking Jalyn and are concerned about any side effects, it is best to consult your healthcare provider for personalized advice.

What should I know about storage and disposal of this medication?

Here are some key points to be aware of:

Storage:

• Store the medication in the original container it came in, tightly closed, and out of reach of children and pets.
• Keep Jalyn at a temperature between 68°F and 77°F (20°C and 25°C).
• Store the medication in a dry place, away from excessive moisture and direct sunlight.

Disposal:

• When you no longer need Jalyn or it reaches its expiration date, it’s important to dispose of it properly. Follow any specific disposal instructions provided by your healthcare provider or pharmacist, or consult your local waste management guidelines for safe disposal methods.

In case of emergency/overdose

• In case of emergency: If you experience a severe allergic reaction or any other serious symptoms after taking Jalyn, such as difficulty breathing, hives, swelling of the face, lips, tongue, or throat, seek immediate medical attention or call emergency services.
• Overdose symptoms: Taking more than the recommended dose of Jalyn can lead to an overdose. Symptoms may include dizziness, fainting, prolonged or painful erection, blurred vision, irregular heartbeat, or changes in consciousness. If you suspect an overdose, contact your local poison control center or seek emergency medical assistance right away.

What other information should I know?

• Regular check-ups: While taking Jalyn, it’s important to attend regular follow-up appointments with your healthcare provider to monitor your progress, discuss any concerns or side effects, and evaluate the effectiveness of the medication.
• Avoid donating blood: If you are taking Jalyn, it’s generally recommended to avoid donating blood during treatment and for at least six months after the last dose. This is to prevent potential harm to a pregnant woman transfused with blood that contains dutasteride.
• Inform healthcare providers: Make sure to inform all healthcare providers involved in your care, including doctors, dentists, and pharmacists, that you are taking Jalyn. This is important to ensure appropriate management of your medications and potential interactions.

Remember, it’s crucial to consult your healthcare provider or pharmacist for personalized advice regarding the storage, disposal, and emergency procedures related to Jalyn, as they can provide guidance tailored to your specific situation.