Why is this medication prescribed?

Iloprost Tromethamine is prescribed for the treatment of several conditions related to blood vessel disorders. It is primarily used for:

• Pulmonary Arterial Hypertension (PAH): Iloprost Tromethamine helps to dilate and relax the blood vessels in the lungs, reducing high blood pressure and improving blood flow in the pulmonary arteries.
• Raynaud’s Phenomenon: This medication improves blood flow to the fingers, toes, ears, and nose by dilating the blood vessels. It is used to reduce the frequency and severity of attacks in individuals with Raynaud’s phenomenon.
• Thromboangiitis Obliterans (Buerger’s Disease): Iloprost Tromethamine is used to improve blood flow to the affected limbs in individuals with this inflammatory condition, helping to relieve symptoms such as pain and ulcers.
• Scleroderma (Systemic Sclerosis): In cases of scleroderma, the medication can improve blood flow and prevent the formation of ulcers and digital ischemia by dilating blood vessels.

How should this medicine be used?

Here are some general guidelines for each form:

• Inhalation Solution: Iloprost tromethamine inhalation is typically administered using a nebulizer device. The solution is breathed in through a mask or mouthpiece. The frequency and duration of inhalation sessions will be determined by your healthcare provider. It is usually recommended to inhale the medication 6 to 9 times per day, with each session lasting 10 to 20 minutes.
• Intravenous (IV) Solution: Iloprost tromethamine IV solution is administered directly into a vein by a healthcare professional. The dosage and infusion rate will be determined by your healthcare provider based on your condition. The infusion is usually given continuously over a period of 6 to 24 hours. The duration and frequency of treatment will vary depending on the individual and the condition being treated.
• Subcutaneous Solution: Iloprost tromethamine subcutaneous solution is injected under the skin, typically in the thigh or abdomen. The injection is usually performed by a healthcare professional. The dosage and frequency of injections will be determined by your healthcare provider based on your condition. It is important to follow their instructions and any specific guidelines provided with the medication.

It is essential to use iloprost tromethamine exactly as prescribed and not to change the dosage or frequency of use without consulting your healthcare provider. If you have any questions or concerns about how to use the medication, it is best to discuss them with your healthcare provider or pharmacist for clarification and guidance.

Other uses for this medicine

Here are some additional uses to consider:

• Raynaud’s phenomenon: Iloprost tromethamine can be used to manage the symptoms of Raynaud’s phenomenon, a condition that causes vasospasms in the fingers and toes, leading to pain and discoloration.
• Thromboangiitis obliterans (Buerger’s disease): Iloprost tromethamine may be used to improve blood flow in patients with thromboangiitis obliterans, a condition that causes inflammation and clotting in small and medium-sized arteries.

What special precautions should I follow?

• Pregnancy and breastfeeding: The safety of iloprost tromethamine during pregnancy and breastfeeding has not been established. It is important to discuss the potential risks and benefits with your healthcare provider if you are pregnant or nursing.
• Bleeding disorders: Iloprost tromethamine can increase the risk of bleeding due to its antiplatelet and vasodilatory effects. It should be used with caution in patients with bleeding disorders or those taking anticoagulant medications.
• Low blood pressure: Iloprost tromethamine can cause a decrease in blood pressure. Caution should be exercised when using this medication in individuals with hypotension or those taking medications that lower blood pressure.
• Renal impairment: Patients with severe renal impairment may require dosage adjustment or closer monitoring when using iloprost tromethamine, as the drug is primarily eliminated through the kidneys.
• Respiratory disorders: Iloprost tromethamine can cause bronchospasm in individuals with underlying respiratory disorders, such as asthma or chronic obstructive pulmonary disease (COPD). It should be used with caution in these patients, and appropriate monitoring is necessary.

As with any medication, it is essential to consult with a healthcare professional or your prescribing physician for accurate information, specific guidelines, and personalized advice regarding the use and precautions associated with iloprost tromethamine.

What special dietary instructions should I follow?

There are no specific dietary instructions that need to be followed for Iloprost Tromethamine. However, it is generally recommended to maintain a healthy and balanced diet while taking any medication.

What should I do if I forget a dose?

If you forget to take a dose of Iloprost Tromethamine, follow these general guidelines:

• Inhaling Iloprost Tromethamine: If you forget to inhale a dose, take it as soon as you remember. However, if it is close to the time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.
• Intravenous (IV) Infusion of Iloprost Tromethamine: Since the IV infusion of Iloprost Tromethamine is usually administered in a healthcare setting under the supervision of medical professionals, the chances of missing a dose are minimal. If, for some reason, a dose is missed during the infusion, your healthcare provider will adjust the schedule accordingly.

What side effects can this medication cause?

Like any medication, it can cause side effects in some individuals. Common side effects of iloprost tromethamine may include:

• Flushing or redness of the face and other parts of the body
• Headache
• Nausea
• Vomiting
• Diarrhea
• Dizziness
• Low blood pressure (hypotension)
• Rapid or irregular heartbeat (tachycardia or arrhythmia)
• Muscle or joint pain
• Swelling of the hands, feet, or ankles
• Cough
• Shortness of breath
• Low levels of potassium in the blood (hypokalemia)
• Skin rash or itching
• Local irritation at the site of administration (such as pain, redness, or swelling)

It’s important to note that not everyone will experience these side effects, and some individuals may experience different or additional side effects. If you are prescribed iloprost tromethamine and notice any concerning or persistent side effects, it is important to inform your healthcare provider for further guidance. They can provide specific advice based on your individual situation.

What should I know about storage and disposal of this medication?

Storage:

• Keep the medication in its original packaging and away from direct light, moisture, and heat.
• Store Iloprost Tromethamine at room temperature, typically between 68°F and 77°F (20°C to 25°C).
• Do not freeze the medication.
• Keep it out of the reach of children and pets.

Disposal:

• Dispose of any unused or expired medication properly and in accordance with local regulations.
• Do not flush Iloprost Tromethamine down the toilet or pour it into drains unless specifically instructed to do so.

In case of emergency/overdose

• If you believe you or someone else may have overdosed on Iloprost Tromethamine, immediately contact emergency services or a poison control center.
• Symptoms of an overdose may include severe dizziness, fainting, rapid heartbeat, chest pain, or difficulty breathing.

What other information should I know?

• Iloprost Tromethamine is usually administered through inhalation using a nebulizer or by intravenous infusion under the supervision of a healthcare professional.
• It is crucial to follow the dosing instructions provided by your doctor or pharmacist.
• Inform your healthcare provider about any other medications, vitamins, or herbal supplements you are taking, as they may interact with Iloprost Tromethamine.
• Inform your healthcare provider if you have any underlying medical conditions, such as liver or kidney problems, before starting this medication.
• Attend regular follow-up appointments to monitor your progress and discuss any concerns or side effects you may be experiencing.

It’s important to consult your healthcare provider or pharmacist for detailed and personalized instructions regarding the storage, disposal, and emergency procedures specific to Iloprost Tromethamine, as they can provide you with the most accurate and up-to-date information based on your individual circumstances.