WARNING

Iloperidone is an antipsychotic medication used to treat certain mental health conditions such as schizophrenia. While it can be effective in managing symptoms, it’s important to be aware of the potential risks associated with taking Iloperidone. Here are some of the risks:

• Side effects: Like any medication, Iloperidone can cause side effects. Common side effects may include drowsiness, dizziness, constipation, dry mouth, and weight gain. It’s essential to discuss any side effects you experience with your healthcare provider.
• Cardiovascular effects: Iloperidone may have an impact on the cardiovascular system. It can cause changes in heart rhythm, which may be serious in some cases. This risk is particularly relevant for individuals with a history of heart problems or those taking medications that can affect heart rhythm.
• Metabolic effects: Antipsychotic medications like Iloperidone can lead to metabolic changes in the body. This includes an increased risk of weight gain, elevated blood sugar levels, and elevated cholesterol and triglyceride levels. Regular monitoring of metabolic parameters is important during treatment.
• Neurological effects: In rare cases, Iloperidone may cause a condition known as neuroleptic malignant syndrome (NMS). NMS is a serious reaction characterized by high fever, muscle stiffness, confusion, and other symptoms. If you experience these symptoms, seek immediate medical attention.
• Other considerations: Iloperidone may interact with other medications, so it’s crucial to inform your healthcare provider about all the medications you are taking. It may also affect cognitive and motor functions, so caution is advised when driving or operating machinery.

It’s important to note that the risks associated with Iloperidone vary from person to person. Some individuals may experience few or no side effects, while others may be more sensitive to the medication. Always consult your healthcare provider for personalized information and guidance regarding the risks and benefits of Iloperidone in your specific situation.

Why is this medication prescribed?

Iloperidone is prescribed for the treatment of certain mental health conditions, primarily schizophrenia. It belongs to a class of medications called atypical antipsychotics. Schizophrenia is a chronic mental disorder characterized by symptoms such as hallucinations, delusions, disorganized thinking, and social withdrawal. Iloperidone helps to reduce these symptoms and improve overall functioning in individuals with schizophrenia.

How should this medicine be used?

When using Iloperidone, it’s essential to follow the prescribed instructions provided by your healthcare provider. Here are some general guidelines:

• Dosage: The dosage of Iloperidone will be determined by your healthcare provider based on your individual needs. It is typically started at a low dose and gradually increased to achieve the desired therapeutic effect.
• Administration: Iloperidone is usually taken orally in the form of tablets. It is typically taken once or twice a day, with or without food. Follow the specific instructions provided by your healthcare provider or on the prescription label.
• Adherence: It’s important to take Iloperidone consistently as prescribed by your healthcare provider. Do not stop taking the medication abruptly or change the dosage without consulting your doctor, as this can lead to withdrawal symptoms or a return of symptoms.
• Regular monitoring: Your healthcare provider may want to monitor your progress and check for any side effects. This may involve periodic visits, blood tests, or other assessments to ensure the medication is working effectively and safely for you.
• Other instructions: It’s important to inform your healthcare provider about any other medications, supplements, or herbal products you are taking, as they may interact with Iloperidone. Additionally, be cautious when consuming alcohol or engaging in activities that require alertness, as Iloperidone can cause drowsiness and impair coordination.

Remember, the specific instructions for using Iloperidone may vary depending on individual factors, so it’s crucial to consult your healthcare provider for personalized guidance on the appropriate use of this medication.

Other uses for this medicine

Iloperidone is primarily used for the treatment of schizophrenia. However, it is important to note that medications are typically prescribed for specific conditions based on their efficacy and safety profiles. Off-label use refers to the use of a medication for purposes other than those officially approved by regulatory authorities. While off-label use of medications is not uncommon, it is important to consult with a healthcare professional for guidance before using any medication for off-label purposes.

What special precautions should I follow?

Regarding special precautions for using Iloperidone, here are some important considerations:

• Allergies: If you have known allergies or hypersensitivity to Iloperidone or any of its components, inform your healthcare provider before starting the medication.
• Medical conditions: Inform your healthcare provider about any pre-existing medical conditions you have, especially heart problems, liver or kidney disease, low white blood cell count, seizures, diabetes, or any other significant medical conditions. These conditions may require special monitoring or adjustment of the dosage.
• Elderly patients: Elderly individuals may be more sensitive to the effects of Iloperidone. They may be at an increased risk of experiencing side effects such as dizziness, drowsiness, and orthostatic hypotension (low blood pressure upon standing). Close monitoring is important in this population.
• Pregnancy and breastfeeding: It is important to discuss the potential risks and benefits of using Iloperidone during pregnancy or while breastfeeding. The medication may pass into breast milk and could potentially have adverse effects on the baby. Your healthcare provider will consider the potential risks and make recommendations based on your specific situation.
• Interactions with other medications: Inform your healthcare provider about all the medications, supplements, and herbal products you are taking, as they may interact with Iloperidone. Certain medications, such as antifungal drugs, antibiotics, and medications that affect heart rhythm, may increase the risk of side effects or affect the effectiveness of Iloperidone.
• Suicide risk: Like other antipsychotic medications, Iloperidone may increase the risk of suicidal thoughts or behavior, particularly in young adults. Close monitoring is important, especially when starting or adjusting the dosage of the medication.

It is crucial to discuss your medical history, current medications, and any specific concerns with your healthcare provider before starting Iloperidone. They will provide you with personalized guidance and precautions based on your individual circumstances.

What special dietary instructions should I follow?

There are no specific dietary instructions that need to be followed for Iloperidone. However, it’s generally recommended to maintain a healthy and balanced diet while taking any medication. Eating a nutritious diet can support overall well-being and may help manage potential side effects, such as weight gain or metabolic changes, associated with Iloperidone or other antipsychotic medications.

What should I do if I forget a dose?

If you forget to take a dose of Iloperidone, here’s what you should do:

• Regular dose: If you remember within a few hours of the scheduled dose, take the missed dose as soon as you remember. However, if it’s close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.
• Long-acting injection (for the extended-release formulation): If you miss a scheduled injection, contact your healthcare provider to determine the next steps. It’s important not to administer the missed dose on your own without medical guidance.

What side effects can this medication cause?

Iloperidone, like any medication, can cause side effects. Not everyone experiences these side effects, and their severity can vary from person to person. Here are some common side effects associated with the use of Iloperidone:

• Extrapyramidal Symptoms: These are movement disorders that can include tremors, muscle stiffness, restlessness, and uncontrollable movements. They may resemble Parkinson’s disease-like symptoms.
• Dizziness: Feeling lightheaded or dizzy may occur, especially when getting up from a sitting or lying position. It’s important to get up slowly to minimize this effect.
• Sedation: Iloperidone can cause drowsiness or sedation, making you feel tired or sleepy.
• Dry Mouth: Some individuals may experience a decrease in saliva production, leading to a dry or sticky sensation in the mouth.
• Constipation: Iloperidone can slow down bowel movements, causing constipation.
• Weight Gain: Some people may experience weight gain while taking Iloperidone. It’s important to monitor your weight regularly and discuss any significant changes with your healthcare provider.
• Increased Prolactin Levels: Iloperidone can raise the levels of the hormone prolactin, which may result in symptoms such as breast enlargement or discharge, menstrual irregularities, or sexual dysfunction.
• Orthostatic Hypotension: This refers to a sudden drop in blood pressure when standing up, leading to dizziness or lightheadedness.
• Increased Heart Rate: In some cases, Iloperidone can cause an increase in heart rate.
• Other Possible Side Effects: Less common side effects may include blurred vision, difficulty urinating, skin rash, sensitivity to sunlight, or changes in blood sugar levels.

It’s important to note that this is not an exhaustive list, and some side effects may be rare but potentially serious. If you experience any new or concerning symptoms while taking Iloperidone, it’s essential to contact your healthcare provider promptly.

Your doctor can provide you with more specific information about the potential side effects of Iloperidone based on your medical history and individual circumstances. They can also guide you on how to manage or minimize any side effects that may occur.

What should I know about storage and disposal of this medication?

Storage of Iloperidone:

• Keep the medication in its original container, tightly closed.
• Store it at room temperature, away from moisture, heat, and light.
• Keep it out of reach of children and pets.

Disposal of Iloperidone:

• Follow any specific disposal instructions provided by your healthcare provider or local regulations.
• If no specific instructions are given, you can usually dispose of the medication by mixing it with an undesirable substance like cat litter or coffee grounds.
• Place the mixture in a sealable bag or container and dispose of it in the household trash.
• Remove any personal information from the medication packaging before disposal.

In case of emergency/overdose

• If you suspect an overdose or experience severe symptoms such as difficulty breathing, extreme drowsiness, confusion, seizures, or loss of consciousness, call emergency services right away.
• You can also contact the National Poison Control Center at 1-800-222-1222 (United States) for guidance on what to do next.
• Do not induce vomiting unless instructed to do so by a medical professional.

What other information should I know?

• It’s crucial to take Iloperidone exactly as prescribed by your healthcare provider. Follow the recommended dosage and do not adjust or stop the medication without consulting your doctor.
• Inform your healthcare provider about any other medications, supplements, or herbal products you are taking, as they may interact with Iloperidone.
• Be aware that Iloperidone may cause drowsiness and impair your thinking or reactions. Avoid driving or engaging in activities that require alertness until you know how the medication affects you.
• Contact your healthcare provider if you experience any concerning side effects or have any questions or concerns about the medication.

Remember, this information serves as a general guide. Always consult your healthcare provider or pharmacist for specific instructions, warnings, and recommendations regarding the storage, disposal, and use of Iloperidone in your individual case.