Why is this medication prescribed?

Hetlioz is a prescription medication that contains the active ingredient tasimelteon. It is primarily prescribed for the treatment of Non-24-Hour Sleep-Wake Disorder (Non-24) in individuals who are totally blind.

Non-24 is a circadian rhythm disorder that affects the sleep-wake cycle. It is more common in individuals who are totally blind because they lack light perception, which is crucial for regulating the internal body clock. As a result, their sleep-wake pattern may gradually shift out of sync with the 24-hour day-night cycle.

Hetlioz works by mimicking the effects of melatonin, a hormone that helps regulate sleep-wake cycles. It acts on melatonin receptors in the brain to promote sleep at night and wakefulness during the day, helping to synchronize the sleep-wake pattern.

How should this medicine be used?

Hetlioz is a prescription medication used to treat a sleep disorder called Non-24-Hour Sleep-Wake Disorder (Non-24). It is important to follow the instructions provided by your healthcare provider and the medication’s label. However, I can provide you with general information on how Hetlioz is typically used.

• Prescription and Dosage: Hetlioz is available in capsule form and should be taken orally. It is only available with a prescription from a healthcare professional. The dosage prescribed may vary depending on your specific condition and medical history. Always follow your healthcare provider’s instructions regarding the dosage.
• Timing: Hetlioz should be taken at the same time every night, before bedtime. It is crucial to establish a consistent sleep routine and take the medication accordingly. Follow the instructions provided by your doctor regarding the specific time to take Hetlioz.
• Administration: Swallow the Hetlioz capsule whole with water. Do not crush, chew, or open the capsule. Taking Hetlioz with or without food does not affect its effectiveness, so you can take it with or without a meal.
• Follow-up appointments: Your healthcare provider may schedule regular follow-up appointments to monitor your response to Hetlioz and adjust the dosage if necessary. It is essential to attend these appointments and discuss any concerns or side effects with your doctor.
• Other considerations: Hetlioz may cause drowsiness or impairment, so it’s important to avoid activities that require mental alertness, such as driving or operating heavy machinery, until you know how the medication affects you.
• Duration of use: Hetlioz is typically used long-term to manage the symptoms of Non-24. It is essential to continue taking Hetlioz as prescribed by your healthcare provider, even if you start feeling better.

Remember, it is crucial to consult your healthcare provider for personalized guidance on the use of Hetlioz, as they will consider your individual medical history and condition when prescribing and monitoring the medication.

Other uses for this medicine

Hetlioz, also known as tasimelteon, is primarily used to treat Non-24-Hour Sleep-Wake Disorder (Non-24), a circadian rhythm sleep disorder that affects individuals who are totally or partially blind. However, Hetlioz may also have other potential uses. It’s important to note that any use of Hetlioz beyond its approved indication would be considered off-label and should only be pursued under the guidance of a healthcare professional.

What special precautions should I follow?

As for special precautions to follow when using Hetlioz, it is crucial to consult with a healthcare provider for personalized advice. However, here are some general precautions and guidelines:

• Medical history and current medications: Inform your healthcare provider about your complete medical history, including any current medications, supplements, or herbal products you are taking. Certain medical conditions or medications may interact with Hetlioz or require dose adjustments.
• Pregnancy and breastfeeding: Hetlioz may not be recommended during pregnancy or breastfeeding. It’s essential to discuss the potential risks and benefits with your healthcare provider if you are pregnant or planning to become pregnant, or if you are breastfeeding or planning to breastfeed.
• Driving and operating machinery: Hetlioz may cause drowsiness or impair your ability to drive or operate machinery. If you experience such effects, avoid engaging in activities that require alertness until you understand how Hetlioz affects you.
• Alcohol and sedatives: Hetlioz can enhance the sedative effects of alcohol and other central nervous system depressants. It is advisable to avoid or limit alcohol consumption and discuss the use of sedatives or other sleep aids with your healthcare provider.
• Light sensitivity: Hetlioz may increase sensitivity to light. Protect your eyes from excessive sunlight or bright indoor lights, especially in the evening and at night.
• Side effects: Be aware of potential side effects of Hetlioz, such as headache, drowsiness, abnormal dreams, dizziness, and nausea. If you experience any concerning side effects, notify your healthcare provider.

Remember, these precautions are not exhaustive, and it is essential to consult with your healthcare provider for specific recommendations based on your individual circumstances. They will provide you with the most accurate and up-to-date information regarding the use of Hetlioz and any precautions you should follow.

What special dietary instructions should I follow?

There are no specific dietary restrictions associated with Hetlioz. However, it is always advisable to maintain a healthy and balanced diet as recommended by your healthcare provider.

What should I do if I forget a dose?

If you forget to take a dose of Hetlioz, take it as soon as you remember. However, if it is close to the time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double up on doses to make up for a missed dose.

What side effects can this medication cause?

Hetlioz (tasimelteon) can cause side effects in some individuals. Common side effects may include:

• Headache
• Sleepiness or drowsiness
• Abnormal dreams
• Upper respiratory or sinus infection
• Elevated liver enzymes (seen in blood tests)
• Diarrhea
• Abdominal pain
• Back pain
• Mood changes, such as irritability or depression
• Increased levels of creatine phosphokinase (CPK) in the blood (seen in blood tests)

It’s important to note that not everyone will experience these side effects, and some individuals may experience different or no side effects at all. If you experience any concerning or persistent side effects while taking Hetlioz, it is recommended to contact your healthcare provider for further evaluation and guidance.

This list of side effects is not exhaustive, and there may be other potential side effects associated with Hetlioz. It’s always advisable to read the medication’s prescribing information and consult with your healthcare provider or pharmacist for a comprehensive understanding of the potential side effects specific to your situation.

What should I know about storage and disposal of this medication?

Storage of Hetlioz:

• Store Hetlioz at room temperature, away from moisture and heat.
• Keep it in its original container, tightly closed, and out of reach of children or pets.
• Do not use Hetlioz if it has expired or if the medication appears damaged or discolored.

Disposal of Hetlioz:

• Follow your local regulations and guidelines for the disposal of medication.
• Do not flush Hetlioz down the toilet or pour it down the drain unless instructed to do so.
• Consult your pharmacist or healthcare provider on how to properly dispose of unused or expired medication.

In case of emergency/overdose

In case of emergency/overdose:

• If you suspect an overdose or experience severe symptoms after taking Hetlioz, such as extreme drowsiness, confusion, or difficulty breathing, call emergency services immediately.
• Contact your local poison control center or seek medical attention right away.
• Provide healthcare professionals with information about the medication and the amount taken, if possible.

What other information should I know?

Other important information:

• Inform your healthcare provider about any other medications, supplements, or herbal products you are taking, as they may interact with Hetlioz.
• Hetlioz may cause drowsiness or impair your ability to drive or operate machinery. Avoid engaging in such activities until you know how Hetlioz affects you.
• Inform your healthcare provider about any pre-existing medical conditions, including liver or kidney problems.
• Attend regular check-ups and follow-up appointments with your healthcare provider to monitor your response to Hetlioz and any potential side effects.

Remember to always consult the prescribing information provided with Hetlioz and reach out to your healthcare provider or pharmacist if you have any specific questions or concerns about storage, disposal, emergencies, or any other aspects of using the medication.