Why is this medication prescribed?

Erlotinib is a medication primarily prescribed for the treatment of certain types of cancer, notably non-small cell lung cancer (NSCLC) and pancreatic cancer. It belongs to a class of drugs known as tyrosine kinase inhibitors (TKIs). Erlotinib works by blocking the action of a specific protein called the epidermal growth factor receptor (EGFR), which is involved in the growth and spread of cancer cells.

How should this medicine be used?

Here’s how Erlotinib is typically used:

• Dosage: The dosage of Erlotinib can vary depending on the specific type of cancer being treated, the patient’s overall health, and other factors. It is usually taken once a day, either with or without food.
• Administration: Erlotinib is taken orally in the form of a tablet. It’s essential to follow the instructions provided by your doctor or pharmacist regarding when and how to take the medication.
• Consistency: It’s important to take Erlotinib consistently at the same time each day to maintain a steady level of the drug in your body.
• Do not crush or chew: Erlotinib tablets should be swallowed whole with a glass of water. Do not crush, chew, or dissolve the tablets, as this can alter the way the medication is absorbed and decrease its effectiveness.
• Follow-up: Your doctor will likely monitor your progress regularly while you’re taking Erlotinib. They may adjust your dosage or treatment plan based on how well you respond to the medication and any side effects you experience.
• Duration: Treatment with Erlotinib may continue for as long as it is effective in controlling the cancer or until unacceptable side effects occur.

It’s crucial to communicate with your healthcare provider throughout your treatment with Erlotinib, reporting any side effects or concerns promptly. They can provide guidance on managing side effects and adjust your treatment plan as needed to optimize its effectiveness while minimizing discomfort or risks.

Other uses for this medicine

In addition to its primary use in the treatment of certain types of cancer, Erlotinib may also be prescribed off-label or in clinical trials for other cancer types or conditions. However, it’s essential to note that any such use should be under the guidance of a qualified healthcare provider.

What special precautions should I follow?

Special precautions should be followed when taking Erlotinib. Here are some important considerations:

• Pregnancy and breastfeeding: Erlotinib can cause harm to a developing fetus, so it’s crucial to avoid pregnancy while taking this medication. Effective contraception should be used during treatment, and women should not breastfeed while taking Erlotinib.
• Liver and kidney function: Before starting treatment with Erlotinib, your doctor may perform tests to assess your liver and kidney function. Erlotinib should be used with caution in patients with impaired liver or kidney function, and dosage adjustments may be necessary.
• Skin reactions: Erlotinib can cause skin rash, which may be severe in some cases. It’s important to notify your doctor if you experience any skin changes, such as rash, itching, or blistering. Your doctor may recommend measures to manage these symptoms, such as topical treatments or dose adjustments.
• Eye disorders: Erlotinib may cause eye problems such as dry eyes, blurred vision, or eye irritation. If you experience any changes in vision or eye discomfort while taking Erlotinib, inform your doctor promptly.
• Interstitial lung disease: Rarely, Erlotinib may cause interstitial lung disease, a serious condition that can lead to breathing difficulties. Inform your doctor immediately if you develop new or worsening respiratory symptoms such as cough, shortness of breath, or chest pain.
• Drug interactions: Erlotinib can interact with other medications, including certain antibiotics, antifungal drugs, and proton pump inhibitors. Inform your doctor about all medications, supplements, and herbal products you are taking before starting Erlotinib to avoid potential interactions.
• Regular monitoring: Your doctor will likely monitor your blood counts, liver function, and other parameters regularly while you’re taking Erlotinib to assess its effectiveness and detect any potential side effects early.

Always follow your doctor’s instructions and ask any questions you may have about Erlotinib or your treatment plan to ensure its safe and effective use.

What special dietary instructions should I follow?

There are no specific dietary restrictions associated with Erlotinib. However, it’s essential to follow a balanced diet and stay hydrated during treatment. Discuss any specific dietary concerns with your doctor or a registered dietitian.

What should I do if I forget a dose?

If you miss a dose of Erlotinib, take it as soon as you remember, unless it is almost time for your next dose. In that case, skip the missed dose and take your next dose at the regular time. Do not double the dose to make up for a missed one. If you have any questions or concerns about missed doses, consult your doctor or pharmacist for guidance.

What side effects can this medication cause?

Erlotinib, like any medication, can cause side effects. Not everyone will experience these side effects, and their severity can vary from person to person. Common side effects of Erlotinib may include:

• Skin rash: This is one of the most common side effects of Erlotinib, often appearing as acne-like rash on the face, chest, back, or other parts of the body.
• Diarrhea: Some people may experience diarrhea, which can be mild to severe.
• Fatigue: Erlotinib may cause fatigue or weakness.
• Nausea and vomiting: Some individuals may experience nausea or vomiting while taking Erlotinib.
• Loss of appetite: Decreased appetite is a common side effect of Erlotinib.
• Dry skin: Erlotinib can cause dryness and itching of the skin.
• Mouth sores: Some people may develop sores or ulcers in the mouth or on the lips.
• Eye irritation: Erlotinib may cause eye problems such as dry eyes, blurred vision, or eye irritation.
• Cough: A persistent cough may occur in some individuals.
• Shortness of breath: Difficulty breathing or shortness of breath can occur rarely and may be a sign of a serious condition such as interstitial lung disease.

It’s essential to report any side effects to your doctor, even if they seem minor. Your doctor can provide guidance on managing side effects and may adjust your treatment plan if needed to minimize discomfort or risks. Additionally, seek immediate medical attention if you experience severe or concerning side effects while taking Erlotinib.

What should I know about storage and disposal of this medication?

Storage and disposal of Erlotinib:

• Storage: Store Erlotinib tablets at room temperature away from moisture and heat. Keep the medication in its original container, tightly closed, and out of reach of children and pets.
• Disposal: Dispose of any unused or expired Erlotinib tablets according to local regulations or guidelines. Do not flush them down the toilet or pour them into a drain unless instructed to do so. Consult your pharmacist or local waste disposal authority for proper disposal methods.

In case of emergency/overdose

In case of emergency or suspected overdose of Erlotinib, seek immediate medical attention or contact your local poison control center. Overdose symptoms may include severe diarrhea, vomiting, skin rash, and other adverse reactions. It’s essential to follow medical advice promptly in such situations.

What other information should I know?

• Follow-up appointments: Attend all scheduled follow-up appointments with your doctor while taking Erlotinib. Regular monitoring is essential to assess your response to treatment and detect any potential side effects or complications early.
• Lab tests: Your doctor may order regular blood tests and other laboratory tests to monitor your liver function, kidney function, and overall health during treatment with Erlotinib.
• Avoid grapefruit: Avoid consuming grapefruit or grapefruit juice while taking Erlotinib, as it may interact with the medication and increase the risk of side effects.
• Inform healthcare providers: Inform all healthcare providers involved in your care, including dentists and pharmacists, that you are taking Erlotinib. This is important for avoiding potential drug interactions and ensuring safe and effective treatment.
• Patient assistance programs: If you have difficulty affording Erlotinib, ask your doctor or pharmacist about patient assistance programs or other resources that may be available to help reduce the cost of the medication.
• Travel considerations: If you plan to travel while taking Erlotinib, ensure you have an adequate supply of medication with you and carry it in its original container. Be aware of any travel restrictions or special precautions related to your condition and treatment.

Always follow your doctor’s instructions and ask any questions you may have about Erlotinib or your treatment plan to ensure its safe and effective use.