WARNING

Erivedge (generic name: Vismodegib) is a medication primarily used to treat basal cell carcinoma (BCC), a type of skin cancer. While effective, it does come with certain risks, including:

• Muscle spasms: Some individuals may experience muscle spasms or cramps while taking Erivedge.
• Hair loss: Hair loss, including hair thinning or alopecia, is a common side effect of Erivedge treatment.
• Fatigue: Many people may experience fatigue or weakness while taking Erivedge.
• Nausea and vomiting: Gastrointestinal side effects like nausea and vomiting are commonly reported with Erivedge use.
• Changes in taste: Some individuals may notice alterations in taste perception, such as a metallic taste in the mouth.
• Weight loss: Weight loss can occur as a result of decreased appetite or gastrointestinal side effects.
• Birth defects: Erivedge can cause severe birth defects if taken during pregnancy. Thus, it is contraindicated in pregnant women and women of childbearing potential must use effective contraception during treatment and for a specified period after discontinuation.
• Musculoskeletal problems: Some individuals may experience musculoskeletal issues such as joint pain or stiffness.
• Liver problems: Liver function abnormalities, including elevated liver enzymes, have been reported with Erivedge use.
• Other potential side effects: Other less common side effects may include diarrhea, constipation, rash, decreased appetite, and decreased potassium levels.

It’s essential for individuals considering or undergoing Erivedge treatment to discuss these risks thoroughly with their healthcare provider and to report any concerning symptoms promptly.

Why is this medication prescribed?

Erivedge (generic name: Vismodegib) is prescribed primarily for the treatment of basal cell carcinoma (BCC), a common type of skin cancer. It is specifically used for locally advanced BCC that cannot be treated with surgery or radiation therapy and for metastatic BCC, where the cancer has spread to other parts of the body.

How should this medicine be used?

How Erivedge is used:

• Dosage: The dosage of Erivedge can vary depending on the individual’s condition and response to treatment. It’s typically taken once daily.
• Administration: Erivedge is available in the form of capsules and should be taken orally with a full glass of water. It can be taken with or without food.
• Follow healthcare provider’s instructions: It’s crucial to follow the dosage and administration instructions provided by the healthcare provider. Do not adjust the dosage or stop taking Erivedge without consulting a healthcare professional.
• Pregnancy precautions: Due to the risk of severe birth defects, Erivedge should not be taken during pregnancy. Women of childbearing potential should use effective contraception during treatment and for a specified period after discontinuation.
• Regular monitoring: Healthcare providers may conduct regular monitoring, including blood tests, to assess the response to treatment and monitor for any potential side effects.
• Storage: Erivedge should be stored at room temperature away from moisture and heat.
• Adherence: It’s essential to take Erivedge consistently as prescribed by the healthcare provider to achieve the best possible outcomes.

As with any medication, individuals should discuss any questions or concerns about Erivedge treatment with their healthcare provider.

Other uses for this medicine

Erivedge (generic name: Vismodegib) is primarily used for the treatment of basal cell carcinoma (BCC), a type of skin cancer. However, there are no other approved uses for Erivedge at the moment.

What special precautions should I follow?

Special precautions to follow while taking Erivedge:

• Pregnancy precautions: Erivedge can cause severe birth defects if taken during pregnancy. Therefore, it’s crucial to avoid becoming pregnant while taking Erivedge and for a specified period after discontinuation. Effective contraception should be used by women of childbearing potential during treatment and for a specified time afterward.
• Liver function monitoring: Healthcare providers may monitor liver function regularly during Erivedge treatment due to the potential risk of liver problems, including elevated liver enzymes.
• Muscle and skeletal issues: Some individuals may experience muscle spasms or musculoskeletal problems while taking Erivedge. If you experience any unusual muscle pain, weakness, or stiffness, it’s important to inform your healthcare provider.
• Sun protection: Since BCC is a type of skin cancer, it’s essential to practice sun protection measures, such as wearing protective clothing and using sunscreen, while undergoing Erivedge treatment and afterward.
• Regular follow-ups: Regular follow-up appointments with healthcare providers are important to monitor the response to treatment, assess for any potential side effects, and adjust the treatment plan as needed.
• Inform healthcare provider: It’s crucial to inform your healthcare provider about all medications, supplements, and herbal products you are taking, as they may interact with Erivedge.
• Adherence to dosage: It’s important to take Erivedge exactly as prescribed by the healthcare provider. Do not adjust the dosage or stop taking the medication without consulting your healthcare provider.
• Storage: Erivedge should be stored at room temperature away from moisture and heat, in its original packaging.

Following these precautions and guidelines can help ensure safe and effective use of Erivedge for the treatment of basal cell carcinoma. Always consult with your healthcare provider if you have any questions or concerns about your treatment.

What special dietary instructions should I follow?

There are no specific dietary instructions for Erivedge. However, it’s important to maintain a healthy and balanced diet while undergoing treatment. If you have any concerns about your diet or nutrition during Erivedge treatment, it’s best to consult with your healthcare provider or a registered dietitian.

What should I do if I forget a dose?

If you forget to take a dose of Erivedge, take it as soon as you remember, unless it’s almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you’re unsure about what to do, consult with your healthcare provider or pharmacist for guidance.

What side effects can this medication cause?

Erivedge (generic name: Vismodegib) can cause various side effects, ranging from mild to severe. Common side effects of Erivedge include:

• Muscle spasms or cramps
• Hair loss (alopecia) or hair thinning
• Fatigue or weakness
• Nausea and vomiting
• Changes in taste perception, such as a metallic taste in the mouth
• Weight loss due to decreased appetite or gastrointestinal side effects
• Diarrhea or constipation
• Rash or skin reactions
• Decreased potassium levels
• Decreased appetite
• Joint pain or stiffness
• Liver function abnormalities, including elevated liver enzymes

Serious side effects of Erivedge may include:

• Severe birth defects if taken during pregnancy
• Liver problems, which may manifest as jaundice, dark urine, or abdominal pain
• Severe allergic reactions, including rash, itching, swelling of the face, tongue, or throat, severe dizziness, or trouble breathing

It’s important to report any side effects experienced while taking Erivedge to your healthcare provider promptly. They can provide guidance on managing side effects and may adjust your treatment plan if necessary. Additionally, individuals should not start or stop taking Erivedge without consulting their healthcare provider.

What should I know about storage and disposal of this medication?

Storage and disposal of Erivedge:

• Storage: Erivedge capsules should be stored at room temperature, away from moisture and heat. Keep them in their original packaging until ready to use.
• Disposal: Dispose of any unused or expired Erivedge capsules properly according to local regulations or guidelines. Do not flush them down the toilet or pour them down the drain unless instructed to do so. Consult with your pharmacist or healthcare provider on the appropriate disposal method.

In case of emergency/overdose

If you suspect an overdose or experience severe symptoms after taking Erivedge, such as severe dizziness, fainting, difficulty breathing, or loss of consciousness, seek immediate medical attention or call your local poison control center at 1-800-222-1222. Be sure to inform medical personnel of the medication taken and the amount ingested.

What other information should I know?

• Follow-up appointments: Regular follow-up appointments with your healthcare provider are essential to monitor your response to treatment, assess for any side effects, and adjust your treatment plan as needed.
• Sun protection: Since Erivedge is used to treat basal cell carcinoma, it’s important to continue practicing sun protection measures, such as wearing protective clothing, using sunscreen, and avoiding prolonged sun exposure.
• Pregnancy and contraception: Erivedge can cause severe birth defects if taken during pregnancy. Women of childbearing potential should use effective contraception during treatment and for a specified period afterward.
• Drug interactions: Inform your healthcare provider about all medications, supplements, and herbal products you are taking, as they may interact with Erivedge. This includes prescription and over-the-counter medications.
• Adherence to dosage: Take Erivedge exactly as prescribed by your healthcare provider. Do not adjust the dosage or stop taking the medication without consulting your healthcare provider.
• Inform healthcare provider: If you experience any new or worsening symptoms while taking Erivedge, or if you have any questions or concerns about your treatment, be sure to inform your healthcare provider promptly.

Following these guidelines can help ensure safe and effective use of Erivedge for the treatment of basal cell carcinoma.