WARNING

Delafloxacin is an antibiotic used to treat bacterial infections. Like any medication, it comes with potential risks. Some common risks associated with taking delafloxacin include:

• Allergic reactions: Some individuals may experience allergic reactions such as rash, itching, swelling, or difficulty breathing. If you experience any of these symptoms, seek medical attention immediately.
• Gastrointestinal effects: Delafloxacin may cause gastrointestinal issues such as nausea, vomiting, diarrhea, or abdominal pain. These side effects are usually mild and resolve on their own, but if they persist or worsen, consult your healthcare provider.
• Central nervous system effects: Rarely, delafloxacin can cause central nervous system side effects such as headache, dizziness, or confusion. If you experience severe or persistent headaches or dizziness, inform your doctor.
• Tendonitis and tendon rupture: Like other antibiotics in the fluoroquinolone class, delafloxacin may increase the risk of tendonitis and tendon rupture, particularly in older adults or those with a history of tendon disorders. Stop taking delafloxacin and seek medical attention if you experience tendon pain, swelling, or inflammation.
• Photosensitivity: Delafloxacin may make your skin more sensitive to sunlight, increasing the risk of sunburn or skin rash. Use sunscreen and protective clothing while outdoors, and avoid excessive sun exposure.
• Clostridium difficile infection: Antibiotic use can disrupt the balance of bacteria in the gut, leading to the overgrowth of Clostridium difficile bacteria and causing severe diarrhea and colitis. If you develop persistent diarrhea while taking delafloxacin, contact your doctor immediately.

It’s important to take delafloxacin exactly as prescribed by your healthcare provider and to report any unusual or severe side effects promptly. Always discuss any concerns or questions about medication risks with your doctor or pharmacist.

Why is this medication prescribed?

Delafloxacin tablets are prescribed to treat certain bacterial infections in adults. It belongs to a class of antibiotics called fluoroquinolones, which work by inhibiting the growth of bacteria.

Delafloxacin may be prescribed to treat infections such as:

• Acute bacterial skin and skin structure infections (ABSSSI)
• Community-acquired bacterial pneumonia (CABP)

How should this medicine be used?

Other uses for this medicine

Delafloxacin is primarily prescribed to treat bacterial infections such as acute bacterial skin and skin structure infections (ABSSSI) and community-acquired bacterial pneumonia (CABP). However, there are no widely recognized alternative uses for delafloxacin beyond its approved indications.

What special precautions should I follow?

As for special precautions when using delafloxacin, it’s essential to consider the following:

• Allergies: Inform your healthcare provider if you have had any allergic reactions to delafloxacin or other antibiotics in the fluoroquinolone class, as well as any other allergies you may have.
• Medical history: Before taking delafloxacin, discuss your medical history with your healthcare provider, especially if you have a history of tendon disorders, liver disease, kidney disease, seizures, or myasthenia gravis.
• Pregnancy and breastfeeding: Inform your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding. The safety of delafloxacin during pregnancy and breastfeeding has not been established, so your doctor will weigh the potential risks and benefits before prescribing it.
• Tendon disorders: Delafloxacin, like other fluoroquinolone antibiotics, may increase the risk of tendonitis and tendon rupture, particularly in older adults or those with a history of tendon disorders. If you experience tendon pain, swelling, or inflammation while taking delafloxacin, stop the medication and consult your doctor.
• Photosensitivity: Delafloxacin may make your skin more sensitive to sunlight, increasing the risk of sunburn or skin rash. Use sunscreen and protective clothing while outdoors, and avoid excessive sun exposure.
• Drug interactions: Inform your healthcare provider about all the medications, supplements, and herbal products you are currently taking, as delafloxacin may interact with certain medications, including antacids, sucralfate, and certain blood thinners.
• Clostridium difficile infection: Antibiotic use can disrupt the balance of bacteria in the gut, leading to the overgrowth of Clostridium difficile bacteria and causing severe diarrhea and colitis. If you develop persistent diarrhea while taking delafloxacin, contact your doctor immediately.

Always follow your healthcare provider’s instructions and guidelines when taking delafloxacin, and do not hesitate to ask questions or seek clarification if needed.

What special dietary instructions should I follow?

Regarding special dietary instructions, delafloxacin can be taken with or without food. There are no specific dietary restrictions associated with delafloxacin use. However, it’s essential to maintain a balanced diet and stay hydrated while taking any medication.

What should I do if I forget a dose?

If you forget to take a dose of delafloxacin, take it as soon as you remember. However, if it’s almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you have any concerns about missed doses or need further guidance, consult your healthcare provider or pharmacist.

What side effects can this medication cause?

Delafloxacin, like any medication, can cause side effects. Common side effects of delafloxacin include:

• Nausea and vomiting: Some individuals may experience nausea or vomiting while taking delafloxacin.
• Diarrhea: Diarrhea is a common side effect of delafloxacin treatment. It is usually mild, but if it persists or becomes severe, contact your healthcare provider.
• Headache: Headaches are a relatively common side effect of delafloxacin use.
• Dizziness: Delafloxacin may cause dizziness or lightheadedness in some individuals.
• Abdominal pain: Some people may experience abdominal discomfort or pain while taking delafloxacin.
• Rash: Skin rash or itching may occur as a side effect of delafloxacin. If you develop a rash, especially if it is severe or accompanied by other symptoms, seek medical attention.
• Increased liver enzymes: Delafloxacin can sometimes cause elevated levels of liver enzymes in the blood, which may indicate liver inflammation or damage.
• Tendonitis and tendon rupture: Like other antibiotics in the fluoroquinolone class, delafloxacin may increase the risk of tendonitis and tendon rupture, particularly in older adults or those with a history of tendon disorders.
• Central nervous system effects: Rarely, delafloxacin can cause central nervous system side effects such as confusion, hallucinations, anxiety, depression, or seizures.
• Clostridium difficile infection: Antibiotic use can disrupt the balance of bacteria in the gut, leading to the overgrowth of Clostridium difficile bacteria and causing severe diarrhea and colitis.

It’s essential to report any unusual or severe side effects to your healthcare provider promptly. If you experience a severe allergic reaction, such as difficulty breathing, swelling of the face, lips, tongue, or throat, seek immediate medical attention.

This list does not include all possible side effects of delafloxacin. If you have any concerns about side effects or notice any symptoms while taking delafloxacin, talk to your healthcare provider or pharmacist.

What should I know about storage and disposal of this medication?

Storage and disposal of delafloxacin:

Storage:

• Store delafloxacin tablets at room temperature away from moisture and heat.
• Keep the medication in its original packaging, tightly closed, and out of reach of children and pets.
• Do not store delafloxacin in the bathroom or near the kitchen sink, where it may be exposed to moisture.

Disposal:

• Dispose of any unused or expired delafloxacin tablets properly.
• Do not flush medications down the toilet or pour them into a drain unless instructed to do so.
• Consult your pharmacist or local waste disposal company for guidance on how to safely dispose of delafloxacin.

In case of emergency/overdose

• If you suspect an overdose or experience severe symptoms such as severe dizziness, seizures, or difficulty breathing, seek immediate medical attention or contact a poison control center.
• Be prepared to provide information about the medication, dosage, and any other relevant medical history.

What other information should I know?

• Follow your healthcare provider’s instructions and complete the full course of treatment, even if you start to feel better before the medication is finished.
• Do not share delafloxacin with others or use it for conditions for which it was not prescribed.
• Inform your healthcare provider about all medications, supplements, and herbal products you are taking, as delafloxacin may interact with certain medications.
• If you have any questions or concerns about delafloxacin or its use, consult your healthcare provider or pharmacist for guidance.

Following these guidelines for storage, disposal, and emergency management of delafloxacin can help ensure safe and effective treatment.