WARNING

Corgard (generic name Nadolol) is a medication primarily used to treat high blood pressure and certain heart conditions like angina (chest pain) and arrhythmias (irregular heartbeats). Like any medication, Nadolol carries potential risks and side effects that should be considered:

• Low Blood Pressure (Hypotension): Nadolol can cause a lowering of blood pressure, which may lead to symptoms like dizziness, fainting, or feeling lightheaded, especially when standing up quickly.
• Bradycardia: This is a slower than normal heart rate. Nadolol can decrease heart rate, which may cause symptoms such as fatigue, weakness, or dizziness.
• Heart-related Side Effects: Though less common, Nadolol may worsen heart failure symptoms in some individuals or cause heart block (a problem with the heart’s electrical system).
• Breathing Issues: Nadolol can exacerbate asthma or other respiratory conditions by constricting airways, which may lead to difficulty breathing or wheezing.
• Masking Hypoglycemia Symptoms: Nadolol can mask some of the symptoms of low blood sugar (hypoglycemia), such as rapid heartbeat and tremors, which could delay recognition and treatment of low blood sugar levels in people with diabetes.
• Other Side Effects: These may include nausea, diarrhea, cold hands or feet, depression, or unusual dreams.
• Interactions: Nadolol can interact with other medications, particularly those used to treat heart conditions, blood pressure, or psychiatric disorders, potentially leading to adverse effects or reduced effectiveness.

It’s important for individuals taking Nadolol to be monitored regularly by their healthcare provider to manage these risks and ensure the medication is working effectively for their condition. Always follow your doctor’s instructions and report any concerning symptoms promptly.

Why is this medication prescribed?

Corgard, which is the brand name for Nadolol (its generic name), is primarily prescribed for several medical conditions related to the heart and blood vessels:

• High Blood Pressure (Hypertension): Nadolol helps to lower blood pressure by relaxing blood vessels, making it easier for the heart to pump blood.
• Angina Pectoris: Nadolol is used to prevent angina attacks (chest pain) by reducing the workload of the heart and improving blood flow to the heart muscle.
• Arrhythmias: It is also prescribed to treat certain types of irregular heart rhythms (arrhythmias) by stabilizing the heart’s electrical activity.

How should this medicine be used?

Corgard (Nadolol) is typically taken orally, usually once a day. The dosage prescribed will depend on the individual’s condition and response to the medication. It’s important to follow the specific instructions provided by your doctor. Here are some general guidelines:

• Dosage: The usual starting dose for high blood pressure is 40 mg to 80 mg once daily. For angina or arrhythmias, the starting dose may vary.
• Administration: Nadolol is usually taken with or immediately following a meal to help reduce stomach upset.
• Duration: Continue taking Nadolol as directed by your doctor, even if you feel well. Stopping suddenly can worsen your condition.
• Monitoring: Your doctor may periodically check your blood pressure, heart rate, and overall response to the medication to adjust the dosage if necessary.
• Missed Dose: If you miss a dose, take it as soon as you remember. However, if it’s almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double up on doses to make up for a missed one.

It’s crucial to inform your healthcare provider about any other medications you are taking, including over-the-counter drugs and supplements, as they may interact with Nadolol. Additionally, discuss any medical conditions you have, such as asthma or diabetes, as Nadolol may not be suitable for everyone.

Always consult your doctor if you have any questions or concerns about how to take Nadolol or if you experience any side effects while using this medication.

Other uses for this medicine

• Migraine Prevention: Nadolol is sometimes used off-label to prevent migraines, especially in individuals who experience frequent attacks.
• Essential Tremor: It may be used to help manage essential tremor, a neurological condition causing involuntary shaking.

What special precautions should I follow?

When taking Corgard, it’s important to follow specific precautions to ensure safe and effective use:

• Regular Monitoring: Your doctor may periodically check your blood pressure, heart rate, and overall response to Nadolol. This helps adjust the dosage as needed and monitor for any adverse effects.
• Do Not Stop Abruptly: Suddenly stopping Nadolol can lead to rebound hypertension (sudden increase in blood pressure) or worsening of other heart conditions. If discontinuation is necessary, your doctor will provide instructions on how to gradually taper off the medication.
• Avoid Alcohol: Alcohol can increase the side effects of Nadolol, such as dizziness and drowsiness. It’s generally advised to limit alcohol consumption while taking this medication.
• Caution in Asthma and COPD: Nadolol can cause narrowing of airways, which may worsen symptoms in individuals with asthma or chronic obstructive pulmonary disease (COPD). It should be used cautiously in these patients and may be contraindicated in severe cases.
• Diabetes Management: Nadolol can mask some symptoms of low blood sugar (hypoglycemia), particularly rapid heartbeat. This can make it harder for individuals with diabetes to recognize and treat low blood sugar levels. Close monitoring of blood sugar levels is important.
• Surgery and Anesthesia: Inform your healthcare providers, including dentists and surgeons, that you are taking Nadolol. It may interact with certain anesthetics and affect your heart rate during procedures.
• Pregnancy and Breastfeeding: The safety of Nadolol during pregnancy and breastfeeding is not well-established. Consult with your doctor if you are pregnant, planning to become pregnant, or breastfeeding.
• Other Medications: Inform your doctor about all medications you are taking, including prescription drugs, over-the-counter medications, vitamins, and herbal supplements. Some medications can interact with Nadolol, potentially affecting its effectiveness or increasing the risk of side effects.

Always follow your doctor’s instructions carefully and promptly report any unusual symptoms or concerns while taking Nadolol. This helps ensure safe and effective treatment tailored to your specific health needs.

What special dietary instructions should I follow?

There are no specific dietary restrictions for Nadolol. However, maintaining a healthy diet low in sodium (salt) and saturated fats can complement the management of high blood pressure and heart conditions.

What should I do if I forget a dose?

If you miss a dose of Nadolol, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double up on doses to make up for a missed one.

What side effects can this medication cause?

Corgard (Nadolol) can potentially cause several side effects, although not everyone will experience them. Common side effects include:

• Fatigue or Weakness: Nadolol can cause tiredness or weakness, especially when you first start taking it or if the dosage is increased.
• Dizziness or Lightheadedness: This can occur, particularly when standing up quickly from a sitting or lying position.
• Cold Extremities: Some people may experience cold hands and feet due to reduced blood flow to the extremities.
• Nausea or Upset Stomach: Nadolol may cause gastrointestinal discomfort, such as nausea, vomiting, or diarrhea.
• Sleep Disturbances: This can include trouble sleeping (insomnia) or unusual dreams.
• Depression: Nadolol may rarely contribute to feelings of depression or mood changes.

Less common but more serious side effects that require immediate medical attention include:

• Bradycardia: A slower than normal heart rate, which can cause symptoms like fainting, dizziness, or shortness of breath.
• Worsening of Heart Failure: In some cases, Nadolol can worsen symptoms of heart failure, such as fluid retention and shortness of breath.
• Asthma Exacerbation: Nadolol can constrict airways, potentially worsening symptoms in individuals with asthma or other respiratory conditions.
• Hypoglycemia Masking: Nadolol can mask symptoms of low blood sugar (hypoglycemia), particularly in individuals with diabetes who are taking insulin or other blood sugar-lowering medications.
• Raynaud’s Phenomenon: Nadolol may exacerbate symptoms of Raynaud’s phenomenon, a condition where blood flow to the fingers and toes is reduced in response to cold or stress.
• Allergic Reactions: Although rare, Nadolol can cause allergic reactions such as rash, itching, swelling, severe dizziness, or trouble breathing.

It’s important to report any unusual symptoms or concerns to your doctor while taking Nadolol. They can monitor your health and adjust your treatment plan as needed to minimize side effects and ensure the medication is working effectively for you.

What should I know about storage and disposal of this medication?

Storage of Corgard (Nadolol):

• Room Temperature: Store Nadolol at room temperature between 20-25°C (68-77°F).
• Protect from Light and Moisture: Keep Nadolol in its original container, tightly closed, and protect it from light and moisture.
• Keep Out of Reach of Children and Pets: Store Nadolol in a secure place where children and pets cannot access it.
• Do Not Store in Bathroom: Avoid storing Nadolol in the bathroom or near the kitchen sink, where moisture and heat can degrade the medication.

Disposal of Corgard (Nadolol):

• Proper Disposal: Dispose of any unused Nadolol medication according to local guidelines and regulations. Do not flush medications down the toilet unless instructed to do so.
• Drug Take-Back Programs: If available, use drug take-back programs in your community to dispose of unused medications properly.
• Dispose in Household Trash: If no take-back program is available, seal Nadolol in a container (e.g., a sealed plastic bag) and place it in the household trash. Remove any personal information from the medication packaging before disposal.

In case of emergency/overdose

• Symptoms of Overdose: Symptoms of Nadolol overdose may include severe dizziness, fainting, slow or irregular heartbeat, trouble breathing, or seizures.
• Seek Immediate Medical Attention: If you suspect an overdose or experience severe symptoms, call emergency services (911) or the poison control center (1-800-222-1222) immediately.
• Do Not Delay Treatment: Prompt medical attention is crucial in cases of overdose to minimize potential complications.

What other information should I know?

• Regular Monitoring: Your doctor will monitor your blood pressure, heart rate, and overall response to Nadolol regularly. Keep all scheduled appointments and inform your doctor of any concerns or changes in your health.
• Follow Instructions: Take Nadolol exactly as prescribed by your doctor. Do not change your dosage or stop taking the medication without consulting your doctor first.
• Inform Healthcare Providers: Inform all healthcare providers (doctors, dentists, surgeons, etc.) about your use of Nadolol before undergoing any medical procedures or surgeries.
• Avoid Activities Requiring Alertness: Nadolol can cause dizziness or drowsiness. Use caution when driving, operating machinery, or performing tasks that require alertness until you know how Nadolol affects you.
• Educate Yourself: Understand the potential side effects and interactions of Nadolol. If you have questions or concerns, discuss them with your healthcare provider or pharmacist.

By following these guidelines for storage, disposal, emergency procedures, and other important information, you can ensure safe and effective use of Corgard (Nadolol) as prescribed for your medical condition.