Why is this medication prescribed?

Combivent Respimat Inhalation Spray is prescribed to treat chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema, in patients who require more than one bronchodilator. It contains a combination of two medications:

• Ipratropium bromide (an anticholinergic bronchodilator) – helps to relax and open the airways to improve breathing.
• Albuterol sulfate (a beta agonist bronchodilator) – also helps to relax and open the airways, allowing for easier breathing.

How should this medicine be used?

Combivent Respimat Inhalation Spray is used to manage symptoms of chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema. Here’s how to use it effectively:

Steps for Using Combivent Respimat Inhalation Spray:

• Prepare the Inhaler: Before the first use or if it has not been used for more than 3 days, prime the inhaler by spraying it into the air away from your face, until a fine mist appears.
• Hold the Inhaler: Hold the inhaler upright with the cap closed. Open the cap until it clicks into place.
• Breathe Out: Breathe out gently and away from the inhaler.
• Inhale the Medication: Place the mouthpiece between your lips and close your lips around it. Inhale slowly and deeply through your mouth.
• Press the Dose-Release Button: While inhaling, press the dose-release button on the top of the inhaler to release the medication. You should see a slow-moving mist.
• Hold Your Breath: Hold your breath for 10 seconds or as long as comfortable to allow the medication to reach deep into your lungs.
• Close the Inhaler: Close the cap of the inhaler after each use.

Additional Tips:

• Dosage: Your doctor will prescribe the appropriate number of inhalations and frequency per day. Typically, it is recommended to use 1 inhalation 4 times a day, but follow your doctor’s instructions precisely.
• Cleaning: Clean the inhaler once a week by wiping the mouthpiece with a clean, dry tissue or cloth. Do not wash or put the inhaler in water.
• Storage: Store Combivent Respimat Inhalation Spray at room temperature away from moisture, heat, and direct sunlight.
• Monitoring: Keep track of the number of doses remaining in your inhaler to ensure you have enough medication. Each inhaler contains a specific number of doses, indicated on the packaging.
• Follow-up: Attend follow-up appointments with your doctor to monitor your response to the medication and adjust your treatment plan if necessary.

If you have any questions or concerns about using Combivent Respimat Inhalation Spray, always consult your doctor or pharmacist for guidance. It’s important to use the inhaler correctly to ensure you receive the full benefit of the medication in managing your COPD symptoms effectively.

Other uses for this medicine

Combivent Respimat Inhalation Spray is primarily prescribed for the treatment of chronic obstructive pulmonary disease (COPD), specifically to improve airflow in patients with chronic bronchitis and emphysema who require dual bronchodilation. It is not typically used for other conditions unless specifically directed by your doctor.

What special precautions should I follow?

Special Precautions for Combivent Respimat Inhalation Spray:

• Allergies: Inform your doctor if you are allergic to ipratropium, albuterol, or any other medications before using Combivent Respimat. Also, disclose any allergies to foods, dyes, preservatives, or animals.
• Medical History: Before using Combivent Respimat, especially if it’s your first time using it, inform your doctor about your medical history, especially if you have a history of heart problems (e.g., irregular heartbeat, high blood pressure), seizures, diabetes, or overactive thyroid.
• Pregnancy and Breastfeeding: Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. The effects of Combivent Respimat on pregnancy and breastfeeding infants are not well-studied, so your doctor will weigh the benefits against potential risks before prescribing it.
• Interactions: Inform your doctor about all the medications you are currently taking, including prescription, over-the-counter, herbal supplements, and vitamins. Certain medications may interact with Combivent Respimat, potentially affecting how it works or increasing the risk of side effects.
• Precautions While Using:
  • Avoiding Contact with Eyes: Keep the spray away from your eyes, as it can cause eye pain or discomfort.
  • Avoiding Overuse: Do not exceed the prescribed dose or frequency of use. Using too much can lead to serious side effects.
• Emergency Situations: It’s important to have a rescue inhaler available for sudden breathing problems while using Combivent Respimat. Discuss an action plan with your doctor in case of worsening symptoms.
• Regular Monitoring: Your doctor may periodically check your lung function and overall condition to ensure the medication is working effectively and to monitor for any potential side effects.
• Side Effects: Be aware of potential side effects such as dry mouth, throat irritation, headache, dizziness, or nervousness. If these symptoms persist or worsen, inform your doctor promptly.

Always follow your doctor’s instructions and advice carefully when using Combivent Respimat Inhalation Spray to ensure safe and effective treatment of your COPD symptoms. If you have any concerns or questions about the medication or its use, do not hesitate to discuss them with your healthcare provider.

What special dietary instructions should I follow?

There are typically no specific dietary restrictions associated with using Combivent Respimat Inhalation Spray. However, it’s important to maintain a healthy diet and avoid excessive salt intake if you have hypertension or other heart conditions. Always follow any dietary recommendations provided by your doctor or healthcare provider.

What should I do if I forget a dose?

If you forget to use a dose of Combivent Respimat at the scheduled time, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

What side effects can this medication cause?

Combivent Respimat Inhalation Spray, like any medication, can cause side effects. Not everyone using this medication will experience these side effects, and their severity can vary. Below are some common and less common side effects associated with Combivent Respimat:

Common Side Effects:

• Dry mouth: This is a common side effect due to the anticholinergic component (ipratropium bromide) of Combivent Respimat.
• Throat irritation: You may experience irritation or discomfort in your throat after using the inhaler.
• Headache: Mild to moderate headaches can occur.
• Tremors: Shaking or trembling of the hands or fingers.
• Nervousness: Feeling jittery or anxious.

Less Common Side Effects:

• Dizziness: Feeling lightheaded or dizzy.
• Palpitations: Sensation of irregular or pounding heartbeat.
• Cough: Coughing may occur as a result of irritation or sensitivity.
• Nausea: Feeling sick to your stomach.
• Blurred vision: Vision may become temporarily blurry.
• Difficulty in passing urine: This could occur due to the anticholinergic effects.
• Muscle cramps: Uncommonly, some individuals may experience muscle cramps.

Rare but Serious Side Effects (Seek immediate medical attention):

• Allergic reactions: Symptoms may include rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, or trouble breathing.
• Paradoxical bronchospasm: This is a rare but serious reaction where the medication causes narrowing of the airways instead of widening them, leading to sudden wheezing and shortness of breath.
• Cardiovascular effects: Such as fast or irregular heartbeat, chest pain, or high blood pressure.
• Severe eye pain or discomfort: If the medication accidentally gets into the eyes.
• Seizures: Although rare, seizures have been reported with the use of Combivent Respimat.

Precautions:

• Overuse: Using more than the prescribed dose or frequency can increase the risk of side effects.
• Eye contact: Avoid getting the spray into your eyes, as it can cause discomfort or pain. Rinse your eyes thoroughly with water if this happens.
• Systemic effects: Due to the nature of the medications (ipratropium and albuterol), systemic effects such as cardiovascular effects or changes in blood glucose levels may occur, particularly in susceptible individuals.

If you experience any severe or persistent side effects, or if you notice any other effects not listed here, contact your doctor or healthcare provider immediately. They can provide guidance on managing side effects or adjust your treatment plan if necessary. It’s essential to follow your doctor’s instructions carefully and report any concerns promptly to ensure safe and effective use of Combivent Respimat Inhalation Spray.

What should I know about storage and disposal of this medication?

Storage and Disposal of Combivent Respimat Inhalation Spray:

• Storage: Store Combivent Respimat Inhalation Spray at room temperature, away from moisture, heat, and direct sunlight. The temperature should ideally be between 20 to 25 degrees Celsius (68 to 77 degrees Fahrenheit).
• Avoid freezing: Do not freeze Combivent Respimat.
• Keep out of reach of children: Store the inhaler in a safe place where children cannot reach it.
• Do not puncture: Do not puncture the Combivent Respimat cartridge, even when empty, as it may still contain some medication.

In case of emergency/overdose

• Symptoms of overdose: Symptoms of overdose may include chest pain, fast or irregular heartbeat, nervousness, tremor, seizures, or severe headache.
• Seek immediate medical attention: If you suspect an overdose or if someone has accidentally ingested the medication, call emergency services (911 in the US) or your local poison control center immediately.
• Do not increase dosage: Do not increase the number of inhalations or frequency of use unless directed by your doctor. Overuse can lead to serious side effects and should be avoided.

What other information should I know?

• Regular follow-up: Attend regular follow-up appointments with your doctor to monitor your response to Combivent Respimat and adjust your treatment plan if necessary.
• Rescue inhaler: Always have a rescue inhaler (short-acting bronchodilator) available for sudden breathing difficulties or exacerbations of COPD symptoms.
• Inform healthcare providers: Inform all healthcare providers (doctors, dentists, pharmacists) that you are using Combivent Respimat Inhalation Spray. This is important in case you need emergency treatment or surgery.
• Do not share: Do not share your Combivent Respimat Inhalation Spray with others, even if they have similar symptoms. Each inhaler is prescribed based on individual needs.
• Cleaning: Clean the mouthpiece of the inhaler once a week by wiping it with a clean, dry tissue or cloth. Do not wash the inhaler or submerge it in water.
• Follow instructions carefully: Always follow the instructions provided by your doctor or pharmacist regarding the proper use of Combivent Respimat and any other medications prescribed.
• Educational resources: Ask your doctor or pharmacist for educational resources about COPD management, inhaler techniques, and lifestyle changes that can help improve your symptoms.

By understanding and following these guidelines, you can effectively manage your COPD symptoms with Combivent Respimat Inhalation Spray while minimizing risks and ensuring safe use of the medication. If you have any questions or concerns, do not hesitate to discuss them with your healthcare provider.