Why is this medication prescribed?

Clindesse Vaginal Cream is prescribed for the treatment of bacterial vaginosis (BV). Bacterial vaginosis is a common vaginal infection caused by an imbalance of bacteria in the vagina. Clindesse contains clindamycin, which is an antibiotic that helps to eliminate the bacteria responsible for BV.

How should this medicine be used?

Here’s how Clindesse Vaginal Cream should typically be used:

• Administration: Clindesse is a vaginal cream that is inserted into the vagina using an applicator provided with the medication.
• Dosage: The usual dosage is one applicatorful (approximately 5 grams of cream containing 100 mg of clindamycin) inserted vaginally once at bedtime.
• Instructions:
  • Wash your hands before and after using the cream.
  • Lie on your back with your knees bent or stand with one foot on a chair, or lie down. Insert the applicator deeply into the vagina and press the plunger to release the cream.
  • Withdraw the applicator and dispose of it properly.
• Timing: It is usually recommended to use Clindesse at bedtime to allow the cream to stay in place longer and be more effective.
• Duration: The treatment course typically involves using Clindesse Vaginal Cream for one day only. It is important to follow the full course of treatment as prescribed by your doctor, even if symptoms improve.
• Precautions: Avoid using tampons, douches, spermicides, or other vaginal products during treatment with Clindesse, as they may interfere with the effectiveness of the medication.

Always follow your doctor’s instructions and read the patient information leaflet provided with the medication for specific guidance on usage and potential side effects. If you have any questions or concerns about using Clindesse Vaginal Cream, consult your healthcare provider for advice.

Other uses for this medicine

Clindesse Vaginal Cream is specifically formulated for the treatment of bacterial vaginosis (BV) and is not typically prescribed for other conditions. It contains clindamycin, which is an antibiotic effective against certain types of bacteria commonly associated with BV.

What special precautions should I follow?

Special Precautions for Clindesse Vaginal Cream:

• Allergic Reactions: Inform your doctor if you have had any allergic reactions to clindamycin or any other medications. This is important to prevent potential allergic reactions to Clindesse.
• Pregnancy and Breastfeeding: Discuss with your doctor if you are pregnant, planning to become pregnant, or breastfeeding. While Clindesse is generally considered safe during pregnancy, your doctor will weigh the benefits and potential risks before prescribing it.
• Concomitant Medications: Inform your doctor about all medications you are currently taking, including prescription, over-the-counter, herbal supplements, and vitamins. Some medications may interact with Clindesse, potentially affecting its effectiveness or causing side effects.
• Use as Directed: Follow your doctor’s instructions carefully regarding the application and timing of Clindesse. Using it at bedtime is typically recommended to ensure the cream stays in place for a longer period.
• Avoid Vaginal Irritants: During treatment with Clindesse, avoid using vaginal products such as tampons, douches, spermicides, or other vaginal creams, as they may interfere with the medication’s effectiveness.
• Medical Conditions: If you have a history of gastrointestinal disorders, such as colitis, or if you develop severe or persistent diarrhea during or after using Clindesse, contact your doctor immediately. Clindamycin can sometimes cause inflammation of the colon.
• Follow-Up: It’s important to complete the full course of treatment as prescribed by your doctor, even if symptoms improve or resolve before finishing the medication. This helps to ensure that the infection is completely cleared.

Always consult your healthcare provider for specific guidance tailored to your individual medical history and circumstances. If you experience any unusual symptoms or side effects while using Clindesse Vaginal Cream, contact your doctor promptly for advice.

What special dietary instructions should I follow?

There are generally no specific dietary restrictions associated with the use of Clindesse Vaginal Cream. However, it’s always advisable to maintain a healthy and balanced diet to support overall health and immune function.

What should I do if I forget a dose?

• If it is still bedtime: Use the cream as soon as you remember. Continue with your regular schedule the next day.
• If it is already morning: Skip the missed dose and resume your regular dosing schedule at bedtime. Do not double the dose to catch up.
• Consult Your Doctor: If you are unsure about what to do or if you frequently forget doses, consult your healthcare provider for guidance.

What side effects can this medication cause?

Clindesse Vaginal Cream, like any medication, can cause side effects in some people. The most common side effects reported with the use of Clindesse include:

• Vaginal Irritation: This can manifest as itching, burning, or discomfort in the vaginal area.
• Vaginal Discharge: Changes in vaginal discharge, such as an increase or a different consistency, may occur.
• Headache: Some individuals may experience mild to moderate headaches.
• Abdominal Pain: This can range from mild discomfort to more severe pain.
• Genital Pruritus: Itching in the genital area may occur.
• Nausea: Some people may feel nauseous while using Clindesse.
• Urinary Tract Infection (UTI): There have been reports of urinary tract infections associated with the use of Clindesse.
• Yeast Infection: In some cases, the use of antibiotics like clindamycin can disrupt the normal balance of bacteria and yeast in the vagina, leading to a yeast infection.
• Allergic Reactions: Though rare, allergic reactions such as rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, or trouble breathing may occur. Seek immediate medical attention if you experience any signs of an allergic reaction.
• Gastrointestinal Effects: In rare cases, clindamycin antibiotics can cause severe colitis or pseudomembranous colitis, which may present with severe abdominal pain, persistent diarrhea, and sometimes fever. This requires immediate medical attention and discontinuation of the medication.

It’s essential to report any unusual or severe symptoms to your healthcare provider promptly. They can provide guidance on managing side effects or may recommend discontinuing Clindesse if necessary.

Always follow your doctor’s instructions and read the patient information leaflet provided with Clindesse Vaginal Cream for a comprehensive list of side effects and other important information.

What should I know about storage and disposal of this medication?

Storage and Disposal of Clindesse Vaginal Cream:

• Storage: Store Clindesse Vaginal Cream at room temperature between 20-25°C (68-77°F). Avoid storing it in the bathroom or near the kitchen sink where it could be exposed to moisture. Keep it out of reach of children and pets.
• Disposal: Dispose of Clindesse Vaginal Cream properly according to local regulations or guidelines. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Consult your pharmacist or healthcare provider for the proper disposal method.

In case of emergency/overdose

• Accidental Ingestion: If someone accidentally ingests Clindesse Vaginal Cream, contact a poison control center or emergency room immediately for advice.
• Symptoms of Overdose: While it’s unlikely to overdose on Clindesse Vaginal Cream when used as directed, excessive use could potentially lead to increased side effects. If you suspect an overdose or experience severe symptoms such as severe abdominal pain, persistent diarrhea, or any other unusual symptoms, seek medical attention immediately.

What other information should I know?

• Effectiveness: Clindesse Vaginal Cream is intended for the treatment of bacterial vaginosis (BV). It may not be effective against other types of vaginal infections. Use it only as prescribed by your healthcare provider.
• Follow-Up: Complete the full course of treatment as prescribed, even if symptoms improve before finishing the medication. This helps to ensure the infection is completely treated and reduces the risk of recurrence.
• Avoidance of Certain Products: During treatment with Clindesse, avoid using tampons, douches, spermicides, or other vaginal products unless directed otherwise by your doctor. These products may interfere with the effectiveness of the medication.
• Medical Monitoring: Your doctor may recommend follow-up visits to monitor your response to treatment and assess for any adverse effects.
• Storage and Handling: Keep the medication in its original packaging and handle it with clean hands to avoid contamination.
• Allergic Reactions: If you develop signs of an allergic reaction (e.g., rash, itching/swelling, severe dizziness, difficulty breathing), seek immediate medical attention.
• Consultation: Always consult your healthcare provider or pharmacist if you have any questions or concerns about Clindesse Vaginal Cream, its usage, or potential side effects.

By following these guidelines and instructions, you can use Clindesse Vaginal Cream safely and effectively for the treatment of bacterial vaginosis.