Why is this medication prescribed?

Cervidil is a prescription medication primarily used to help induce labor in pregnant women who are at or near term (after 37 weeks of pregnancy). It contains the hormone-like substance dinoprostone, which is similar to prostaglandin E2. Dinoprostone helps soften and dilate the cervix, which is necessary for labor to begin and progress.

How should this medicine be used?

Here’s how Cervidil is typically used:

• Placement: Cervidil comes as a vaginal insert or suppository. A healthcare provider will insert it into the vagina, typically up near the cervix.
• Duration: It is usually left in place for up to 12 hours. During this time, the dinoprostone slowly releases and works to soften and thin out the cervix.
• Monitoring: While Cervidil is in place, your healthcare provider will monitor your progress closely. This may include checking your cervix periodically to see how it is responding.
• Removal: After up to 12 hours, the Cervidil insert is removed. If labor has not yet started or progressed sufficiently, your healthcare provider may decide to use other methods to induce labor or to repeat the use of Cervidil.

It’s important to follow your healthcare provider’s instructions carefully regarding the use of Cervidil, as the dosage and duration can vary depending on individual circumstances and medical judgment. Additionally, they will monitor you and your baby closely during the induction process to ensure safety and effectiveness.

Other uses for this medicine

• Management of Postpartum Hemorrhage: In some cases, Cervidil may be used to help control bleeding after childbirth by promoting uterine contractions.
• Treatment of Non-Pregnancy Related Conditions: Rarely, Cervidil might be used to treat certain gynecological conditions, such as cervical insufficiency, where the cervix is weak and may cause pregnancy complications.

What special precautions should I follow?

When using Cervidil, several precautions should be taken into consideration to ensure safety and effectiveness:

• Allergy: Inform your healthcare provider if you are allergic to prostaglandins or any other medications, as Cervidil contains dinoprostone.
• Previous Cesarean Section: If you have had a previous cesarean delivery or other uterine surgery, your healthcare provider will carefully assess the risks and benefits of using Cervidil for induction.
• Uterine Rupture: There is a risk of uterine rupture, especially in women with previous uterine surgery or extensive uterine scarring. Close monitoring is essential during the use of Cervidil.
• Fetal Monitoring: Continuous fetal monitoring is typically required during and after Cervidil administration to ensure the baby’s well-being.
• Maternal Monitoring: Your healthcare provider will monitor you closely for any signs of uterine hyperstimulation (excessive contractions), which can be a complication of Cervidil use.
• Preterm Labor: Cervidil should not be used in women with a history of preterm labor or multiple gestations (twins, triplets, etc.) due to the risk of uterine hyperstimulation.
• Other Medical Conditions: Inform your healthcare provider about any other medical conditions you have, such as asthma, cardiovascular disease, or hypertension, as these may affect the safety of using Cervidil.

Always follow your healthcare provider’s instructions and attend all recommended prenatal appointments to ensure that Cervidil is used safely and effectively for your specific circumstances.

What special dietary instructions should I follow?

There are typically no specific dietary restrictions associated with the use of Cervidil. However, it’s generally advisable to maintain a balanced diet and stay hydrated during labor induction. Your healthcare provider may advise you to avoid heavy meals or excessive caffeine intake, as these can potentially affect your comfort during the induction process.

What should I do if I forget a dose?

• If it’s within the recommended timeframe: Your healthcare provider may decide to insert a new dose of Cervidil if the previous one has been in place for less than 12 hours.
• If it’s beyond the recommended timeframe: Your provider may reassess the need for further induction methods or may decide to proceed differently based on your progress and medical condition.

What side effects can this medication cause?

Cervidil (dinoprostone), like any medication, can cause side effects. These side effects can vary in severity and occurrence among individuals. Here are some potential side effects associated with Cervidil:

• Uterine Hyperstimulation: This is a common concern with prostaglandin medications like dinoprostone. It can cause excessive uterine contractions, which may lead to fetal distress or other complications.
• Nausea and Vomiting: Some women may experience nausea or vomiting during or after the administration of Cervidil.
• Diarrhea: Diarrhea can occur as a side effect of Cervidil.
• Fever or Chills: Some women may develop a mild fever or experience chills after receiving Cervidil.
• Headache: Headaches are a possible side effect of dinoprostone.
• Abdominal Pain or Cramping: Mild to moderate abdominal discomfort or cramping can occur with the use of Cervidil.
• Back Pain: Back pain may also be experienced by some women.
• Fetal Heart Rate Changes: Cervidil can sometimes cause changes in the fetal heart rate, which requires close monitoring by healthcare providers.
• Allergic Reactions: Although rare, allergic reactions such as rash, itching, or swelling can occur.
• Uterine Rupture: In rare cases, Cervidil can contribute to uterine rupture, particularly in women with a history of uterine surgery or extensive uterine scarring.

It’s important to note that the occurrence and severity of these side effects can vary widely among individuals. Healthcare providers monitor patients closely during Cervidil administration to promptly address any adverse reactions or complications that may arise. If you experience any concerning symptoms while using Cervidil, it’s crucial to inform your healthcare provider immediately for appropriate evaluation and management.

What should I know about storage and disposal of this medication?

Storage and Disposal of Cervidil:

• Storage: Store Cervidil at room temperature away from moisture and heat. Keep it in its original packaging until ready to use. Avoid freezing.
• Disposal: Unused or expired Cervidil should be disposed of properly according to local regulations or as instructed by your healthcare provider or pharmacist. Do not flush medications down the toilet unless specifically instructed to do so.

In case of emergency/overdose

• Emergency: If you experience severe uterine contractions or any concerning symptoms while using Cervidil, contact your healthcare provider immediately or seek emergency medical attention. Symptoms of uterine hyperstimulation may include intense or frequent contractions, abdominal pain, changes in fetal heart rate, or other signs of distress.
• Overdose: Overdose of Cervidil may lead to excessive uterine stimulation, which can be dangerous for both the mother and the baby. If you suspect an overdose or have concerns about the effects of Cervidil, seek medical help immediately.

What other information should I know?

• Effectiveness: Cervidil is used for cervical ripening and induction of labor under medical supervision. It helps soften the cervix and promote uterine contractions necessary for labor.
• Monitoring: Continuous monitoring of both maternal and fetal well-being is essential during Cervidil administration. This includes regular checks of uterine activity, fetal heart rate monitoring, and maternal vital signs.
• Labor Progress: The response to Cervidil can vary among individuals. Some women may go into labor shortly after its use, while others may require additional interventions or a different approach to labor induction.
• Follow-Up: After the use of Cervidil, follow your healthcare provider’s instructions regarding post-induction care, including monitoring for any signs of complications such as postpartum hemorrhage or uterine infection.
• Patient Education: Ensure you understand the purpose of Cervidil, its potential side effects, and what to expect during the induction process. Ask your healthcare provider any questions you may have to clarify any concerns.

Always use medications like Cervidil under the guidance and supervision of healthcare professionals. They can provide specific instructions tailored to your individual needs and closely monitor your progress to ensure the safest possible outcome for you and your baby.