Why is this medication prescribed?

Calcitriol topical is prescribed primarily for the treatment of plaque psoriasis, a chronic autoimmune condition characterized by red, scaly patches on the skin. Here’s why it’s used and how it should be applied:

• Treatment of Plaque Psoriasis: Calcitriol, a form of vitamin D, helps to regulate skin cell growth and differentiation. In psoriasis, there is abnormal skin cell growth and turnover, leading to the characteristic plaques. Calcitriol helps normalize this process, reducing the thickness and scaling of the plaques.

How should this medicine be used?

How Calcitriol Topical Should be Used:

• Application: It is applied directly to the affected areas of the skin as directed by the healthcare provider.
• Dosage: Typically, a thin layer is applied once daily to the affected skin areas.
• Instructions:
  • Clean and dry the affected area before applying the medication.
  • Apply a small amount to cover the entire affected area.
  • Rub in gently.
  • Wash hands thoroughly after applying, unless hands are the treated area.
• Usage Duration: Follow the prescribed treatment plan. Improvement may be noticeable after several weeks of consistent use.

It’s important to use calcitriol topical exactly as prescribed and not to use more than recommended, as excessive use can lead to side effects. If there are any concerns or questions about its application or effectiveness, consulting with the prescribing healthcare provider is advisable.

Other uses for this medicine

Other Uses for Calcitriol Topical:

• Treatment of Other Types of Psoriasis: While primarily used for plaque psoriasis, calcitriol topical may also be considered for other types of psoriasis such as guttate or inverse psoriasis, depending on the healthcare provider’s recommendation.
• Treatment of Other Hyperproliferative Skin Disorders: There may be instances where calcitriol topical is prescribed off-label for other hyperproliferative skin disorders where abnormal skin cell growth is a concern, though this would be at the discretion of the prescribing healthcare provider.

What special precautions should I follow?

Special Precautions for Calcitriol Topical:

• Avoid Sun Exposure: Calcitriol topical can make your skin more sensitive to sunlight. It is advisable to minimize exposure to natural or artificial sunlight (e.g., sunlamps, tanning beds) during treatment. If exposure cannot be avoided, use sunscreen and wear protective clothing over the treated areas.
• Pregnancy and Breastfeeding: The safety of calcitriol topical during pregnancy or breastfeeding has not been well-established. If you are pregnant, planning to become pregnant, or breastfeeding, discuss the potential risks and benefits with your healthcare provider before using this medication.
• Children and Elderly: Special caution may be needed when using calcitriol topical in children and elderly individuals, as they may be more sensitive to its effects.
• Skin Irritation: Some individuals may experience skin irritation, redness, or itching at the application site. If these symptoms are severe or persistent, notify your healthcare provider.
• Interactions: Inform your healthcare provider about all other medications (prescription and over-the-counter), vitamins, and supplements you are taking, as they may interact with calcitriol topical.
• Medical Conditions: If you have certain medical conditions such as kidney disease or disorders involving calcium metabolism, your healthcare provider may need to monitor you more closely while using calcitriol topical.

Always follow your healthcare provider’s instructions regarding the use of calcitriol topical, including dosage and application instructions, to maximize its effectiveness and minimize potential risks.

What special dietary instructions should I follow?

There are no specific dietary restrictions associated with the use of calcitriol topical. However, maintaining a balanced diet that includes adequate calcium and vitamin D intake may support overall skin health and well-being. If you have concerns about your diet or nutrient intake, consult with a healthcare professional or registered dietitian.

What should I do if I forget a dose?

If you forget to apply a dose of calcitriol topical, apply it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not apply extra medication to make up for a missed dose.

What side effects can this medication cause?

Calcitriol topical, like any medication, can cause side effects. These side effects can vary in severity and occurrence among individuals. Here are some potential side effects associated with calcitriol topical:

• Skin Irritation: This is the most common side effect, including redness, itching, burning sensation, or dryness at the application site.
• Hypercalcemia: In rare cases, excessive absorption of vitamin D from calcitriol topical can lead to elevated levels of calcium in the blood (hypercalcemia). Symptoms may include nausea, vomiting, constipation, increased thirst, increased urination, confusion, and weakness.
• Hypersensitivity Reactions: Some individuals may experience allergic reactions to calcitriol topical, which can manifest as rash, hives, swelling, or difficulty breathing. Seek immediate medical attention if you experience these symptoms.
• Skin Infections: Prolonged use of calcitriol topical can sometimes lead to skin infections, though this is less common.
• Thinning of the Skin: Long-term use of topical corticosteroids, which are sometimes used in combination with calcitriol topical, can lead to skin thinning or changes in skin pigmentation.
• Calcium Metabolism Disorders: In some cases, especially with excessive or prolonged use, there may be alterations in calcium metabolism leading to conditions like hypercalciuria (excess calcium in urine) or nephrocalcinosis (calcium deposits in the kidneys).
• Eye Irritation: Avoid contact with eyes as calcitriol topical can cause irritation if it gets into the eyes.

It’s important to use calcitriol topical exactly as prescribed by your healthcare provider to minimize the risk of side effects. If you experience any unusual symptoms or side effects while using this medication, notify your healthcare provider promptly. They can provide guidance on whether adjustments to your treatment are necessary.

As always, discuss any concerns or questions about side effects with your healthcare provider before starting or continuing treatment with calcitriol topical.

What should I know about storage and disposal of this medication?

Storage of Calcitriol Topical:

• Store calcitriol topical at room temperature, away from excessive heat and moisture.
• Keep the medication tightly closed in its original container to protect it from light and air.
• Do not freeze calcitriol topical.

Disposal of Calcitriol Topical:

• Dispose of unused or expired calcitriol topical as per local regulations or guidelines provided by your healthcare provider or pharmacist.
• Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Proper disposal helps prevent environmental contamination.

In case of emergency/overdose

• In case of accidental ingestion or overdose of calcitriol topical, seek medical assistance or contact a Poison Control Center immediately.
• Symptoms of overdose may include symptoms of hypercalcemia (elevated blood calcium levels), such as nausea, vomiting, constipation, confusion, weakness, and increased thirst or urination.

What other information should I know?

• Follow Instructions: Use calcitriol topical exactly as prescribed by your healthcare provider. Do not exceed the recommended dose or frequency of application.
• Avoid Eyes and Mucous Membranes: Avoid getting calcitriol topical in the eyes, mouth, or mucous membranes. If accidental contact occurs, rinse thoroughly with water.
• Sun Exposure: Limit exposure to sunlight and UV light during treatment. Use sunscreen and wear protective clothing over treated areas to prevent sunburn.
• Consultation: Inform your healthcare provider about all medications (including over-the-counter medications, vitamins, and supplements) you are taking, to avoid potential interactions.
• Regular Follow-Up: Attend scheduled appointments with your healthcare provider for monitoring and evaluation of your condition and response to treatment.

By following these guidelines, you can ensure safe and effective use of calcitriol topical for the treatment of plaque psoriasis or other conditions as prescribed. If you have any concerns or questions about its use, storage, or disposal, do not hesitate to consult your healthcare provider or pharmacist for clarification.