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Zylet (Loteprednol Etabonate/Tobramycin) – 0.5-0.3% Ophthalmic Suspension 2.5ml

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Zylet Drops are used for:

Treating certain types of eye inflammation in which an
infection or risk of infection is present.

Zylet Drops are a combination of a corticosteroid and
antibiotic. It reduces inflammation and treats or protects against infection due
to certain bacteria.

Do NOT use Zylet Drops if:

  • you are allergic
    to any ingredient in Zylet Drops or to similar medicines, including
    corticosteroids or aminoglycoside antibiotics.

  • you have a viral disease in the
    eye, including herpes simplex keratitis (dendritic keratitis), vaccinia, or

  • you have a mycobacterial or
    fungal infection of the eye

Before using Zylet Drops:

Some medical conditions may interact with Zylet Drops. Tell
your doctor or pharmacist if you have any medical conditions, especially if any
of the following apply to you:

  • if you are pregnant, planning to
    become pregnant, or are breast-feeding

  • if you are taking any
    prescription or nonprescription medicine, herbal preparation, or dietary

  • if you have
    to medicines, foods, or other substances

  • if you have glaucoma, thinning of
    certain parts of the eye (the cornea or the sclera), or a history of herpes
    simplex infection, or have recently had cataract surgery

  • if you have diabetes or wear
    contact lenses

Some MEDICINES MAY INTERACT with Zylet Drops. Tell your
health care provider if you are taking any other medicines, especially any of
the following:

  • Certain diuretic medicines (eg,
    furosemide), cyclosporine, nonsteroidal anti-inflammatory medicines
    (NSAIDs), or other medicines containing aminoglycoside antibiotics (eg,
    tobramycin, gentamicin) because the risk of their side effects may be
    increased by Zylet Drops

How to use Zylet Drops:

Use Zylet Drops as directed by your doctor. Check the label
on the medicine for exact dosing instructions.

  • Zylet Drops are to be used as eye
    drops. It is not to be injected into the eye.

  • Shake well before each use.
  • To use Zylet Drops in the eye,
    first, wash your hands. Tilt your head back. Using your index finger, pull
    the lower eyelid away from the eye to form a pouch. Drop the medicine into
    the pouch and gently close your eyes. Immediately use your finger to apply
    pressure to the inside corner of the eyelid for 1 to 2 minutes. Do not
    blink. Remove excess medicine around your eye with a clean,
    dry tissue, being careful not to touch your eye. Wash your hands to remove
    any medicine that may be on them.

  • To prevent germs from
    contaminating your medicine, do not touch the applicator tip to any surface,
    including the eye. Keep the container tightly closed.

  • To clear up your infection
    completely, take/use Zylet Drops for the full course of treatment. Keep
    taking/using it even if you feel better in a few days.

  • Zylet Drops are usually used for
    a maximum of 2 weeks. If it is used for longer than 10 days, eye
    may be required.

  • If you miss a dose of Zylet
    Drops, use it as soon as possible. If it is almost time for your next dose,
    skip the missed dose and go back to your regular dosing schedule. Do not use
    2 doses at once.

Important safety information:

  • Zylet Drops may cause blurred
    vision. Use Zylet Drops with caution. Do not drive or perform other possibly
    unsafe tasks if you cannot see clearly.

  • If your symptoms do not get
    better after 2 days or if they get worse, contact your health care provider.

  • Soft contact lenses may absorb a
    chemical in Zylet Drops. Do not wear contact lenses while you are using
    Zylet Drops.

  • Tell your doctor or dentist
    that you take Zylet Drops before you receive any medical or dental care,
    emergency care, or surgery.

  • Zylet Drops only works against
    bacteria; it does not treat viral infections (eg, the

  • Be sure to use Zylet Drops for
    the full course of treatment. If you do not, the medicine may not clear up
    your infection completely. The bacteria could also become less sensitive to
    this or other medicines. This could make the infection harder to treat in
    the future.

  • Long-term or repeated use of
    Zylet Drops may cause a second infection. Tell your doctor if signs of a
    second infection occur. Your medicine may need to be changed to treat this.

  • Lab tests, including eye
    examinations, may be performed while you use Zylet Drops. These tests may be
    used to monitor your condition or check for side effects. Be sure to keep
    all doctor and lab appointments.

  • Zylet Drops should not be used in
    safety and effectiveness in children have not been confirmed.

    you think you may be pregnant, contact your doctor. You will need to discuss
    the benefits
    and risks of using Zylet Drops while you are pregnant. It is not known if
    Zylet Drops are found in breast milk. If you are or will be breast-feeding
    while you use Zylet Drops, check with your doctor. Discuss any possible
    risks to your baby.

Possible side effects of Zylet Drops:

All medicines may cause side effects, but many people have
no, or minor, side effects. Check with your doctor if any
of these most COMMON side effects persist or become bothersome:

Burning or stinging upon using Zylet Drops; mild itching,
discomfort, or redness of the eye.

Seek medical attention right away if any of these SEVERE
side effects occur:

Severe allergic
(rash; hives; itching; difficulty breathing; tightness in
the chest; swelling of the mouth, face, lips, or tongue); blurred vision or
other vision changes; sensitivity to light; severe or worsening pain, redness,
swelling, or discharge from the eye or eyelid; unusual tearing.

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