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Zonisamide 50mg Capsules – Generic Zonegran

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Zonisamide is used for:

Treating certain types of seizures (partial seizures) in
patients with epilepsy. It is used along with other medicines. It may also be
used for other conditions as determined by your doctor.

Zonisamide is an anticonvulsant. Exactly how Zonisamide works
is not known.

Do NOT use Zonisamide if:

  • you are allergic
    to any ingredient in Zonisamide or to a sulfonamide (eg, sulfamethoxazole)

  • you have kidney failure

Before using Zonisamide :

Some medical conditions may interact with Zonisamide . Tell
your doctor or pharmacist if you have any medical conditions, especially if any
of the following apply to you:

  • if you are pregnant, planning to
    become pregnant, or are breast-feeding

  • if you are taking any
    prescription or nonprescription medicine, herbal preparation, or dietary
    supplement

  • if you have
    allergies
    to medicines, foods, or other substances (including
    tartrazine)

  • if you are allergic to aspirin
  • if you have a history of status
    epilepticus (eg, long periods of continuous seizure activity or a series of
    seizures without a full return to consciousness)

  • if you have a history of liver or
    kidney problems, kidney stones, lung or breathing problems, mental or mood
    problems, or suicidal thoughts or actions

  • if you have a skin
    rash

  • if you have diarrhea, will be
    having surgery, or are on a ketogenic diet

Some MEDICINES MAY INTERACT with Zonisamide . Tell your
health care provider if you are taking any other medicines, especially any of
the following:

  • Anticholinergics (eg,
    benztropine) or carbonic anhydrase inhibitors (eg, acetazolamide) because
    the risk of heatstroke or high blood acid levels may be increased

How to use Zonisamide :

Use Zonisamide as directed by your doctor. Check the label on
the medicine for exact dosing instructions.

  • An extra patient leaflet may be
    available with Zonisamide . Talk to your pharmacist if you have questions
    about this information.

  • Take Zonisamide by mouth with or
    without food.

  • Swallow Zonisamide whole. Do not
    break, crush, or chew before swallowing.

  • Drink plenty of liquids (6 to 8
    glasses of water a day) while taking Zonisamide to help prevent kidney
    stones.

  • Do not suddenly stop taking
    Zonisamide . Suddenly stopping Zonisamide may cause seizures to occur more
    often. If you need to stop Zonisamide , follow your doctor’s instructions
    for slowly lowering your dose.

  • If you miss a dose of Zonisamide
    , take it as soon as possible. If it is almost time for your next dose, skip
    the missed dose. Go back to your regular dosing schedule. Do not take 2
    doses at once.

Important safety information:

  • Zonisamide may cause dizziness,
    drowsiness, or vision changes. These effects may be worse if you take it
    with alcohol or certain medicines. Use Zonisamide with caution. Do not drive
    or perform other possibly unsafe tasks until you know how you react to it.

  • Zonisamide may reduce sweating,
    which could increase the risk of heat stroke, especially in children.
    The risk is greater in hot weather and/or during vigorous exercise. Drink
    plenty of fluids. Dress lightly while in hot climates or when exercising.
    Check carefully for signs of decreased sweating. If this occurs, promptly
    seek cooler or air-conditioned shelter and/or stop exercising. Seek medical
    attention right away if you have an unexplained fever, or if you have mental
    or mood changes, headache, or dizziness.

  • Zonisamide may cause high blood
    acid levels (metabolic acidosis). The risk may be greater in children and in
    patients with kidney problems, severe breathing problems, or diarrhea. It
    may also be greater in patients who are taking certain other medicines (eg,
    acetazolamide), will be having surgery, or are on a ketogenic diet. Over a
    period of time, metabolic acidosis may cause kidney problems, bone problems,
    or decreased growth in children. Contact your doctor immediately if you
    experience fast breathing, unusual weakness or fatigue, sluggishness,
    fainting, persistent loss of appetite, or irregular heartbeat.

  • Contact your doctor at once if
    your seizures worsen or if you develop a skin rash.

  • Tell your doctor or dentist that
    you take Zonisamide before you receive any medical or dental
    care
    , emergency care, or surgery.

  • Carry an ID card at all times
    that says you take Zonisamide .

  • This product may contain
    tartrazine dye (FD&C Yellow No. 5). This may cause an
    allergic reaction
    in some patients. If you have ever had an
    allergic reaction to tartrazine, ask your pharmacist if your product has
    tartrazine in it.

  • Women who take Zonisamide should
    use effective birth
    control
    while using Zonisamide .

  • Lab tests, including kidney
    function tests or blood bicarbonate levels, may be performed while you use
    Zonisamide . These tests may be used to monitor your condition or check for
    side effects. Be sure to keep all doctor and lab appointments.

  • Zonisamide should be used with
    extreme caution in CHILDREN younger than 16 years old; safety and
    effectiveness in these children have not been confirmed. CHILDREN may be at
    a higher risk of heatstroke and metabolic acidosis.

  • PREGNANCY AND BREAST-FEEDING:
    Zonisamide may cause harm to the fetus. Do not become pregnant while you are
    using it. If you become pregnant, contact your doctor. You will need to
    discuss the benefits and risks of using Zonisamide while you are pregnant.
    It is not known if Zonisamide is found in breast milk. If you are or will be
    breast-feeding while you use Zonisamide , check with your doctor. Discuss
    any possible risks to your baby.

Possible side effects of Zonisamide :

All medicines may cause side effects, but many people have
no, or minor, side effects. Check with your doctor if any
of these most COMMON side effects persist or become bothersome:

Abnormal skin sensations; diarrhea; dizziness; drowsiness;
flu-like symptoms; headache; irritability; loss of appetite; nausea; stomach
upset; tiredness; trouble sleeping.

Seek medical attention right away if any of these SEVERE
side effects occur:

Severe allergic
reactions
(rash; hives; itching; difficulty breathing; tightness in
the chest; swelling of the mouth, face, lips, or tongue); bone pain; changes
in the amount of urine produced; confusion; dark or bloody urine; decreased
sweating; double vision or other vision problems; fainting; fast breathing;
fast, slow, or irregular heartbeat; fever, chills, or sore throat; loss of
coordination; memory problems; mental or mood changes (eg, agitation,
depression); mouth sores; painful urination; persistent loss of appetite; red,
swollen, blistered, or peeling skin; severe muscle pain or weakness; severe or
persistent drowsiness; sluggishness; sudden stomach or back pain; suicidal
thoughts or actions; swelling of the hands, ankles, or feet; tremor; trouble
speaking or other speech problems; trouble thinking or concentrating; unusual
bruising or bleeding; unusual eye movements; unusual or disturbing thoughts;
unusual tiredness or weakness.

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