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Zonegran 25mg Capsules

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Zonegran is used for:

Treating certain types of seizures (partial seizures) in patients with epilepsy. Zonegran is used along with other medicines. Zonegran may also be used for other conditions as determined by your doctor.

Zonisamide is an anticonvulsant. Exactly how Zonisamide works is not known.

Do NOT use Zonisamide if:

  • you are allergic to any ingredient in Zonisamide or to a sulfonamide (eg, sulfamethoxazole)
  • you have kidney failure

Before using Zonisamide :

Some medical conditions may interact with Zonisamide . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances (including tartrazine)
  • if you are allergic to aspirin
  • if you have a history of status epilepticus (eg, long periods of continuous seizure activity or a series of seizures without a full return to consciousness)
  • if you have a history of liver or kidney problems, kidney stones, lung or breathing problems, mental or mood problems, or suicidal thoughts or actions
  • if you have a skin rash
  • if you have diarrhea, will be having surgery, or are on a ketogenic diet

Some MEDICINES MAY INTERACT with Zonisamide . Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Anticholinergics (eg, benztropine) or carbonic anhydrase inhibitors (eg, acetazolamide) because the risk of heatstroke or high blood acid levels may be increased

How to use Zonisamide :

Use Zonisamide as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • An extra patient leaflet may be available with Zonisamide . Talk to your pharmacist if you have questions about this information.
  • Take Zonisamide by mouth with or without food.
  • Swallow Zonisamide whole. Do not break, crush, or chew before swallowing.
  • Drink plenty of liquids (6 to 8 glasses of water a day) while taking Zonisamide to help prevent kidney stones.
  • Do not suddenly stop taking Zonisamide . Suddenly stopping Zonisamide may cause seizures to occur more often. If you need to stop Zonisamide , follow your doctor’s instructions for slowly lowering your dose.
  • If you miss a dose of Zonisamide , take it as soon as possible. If it is almost time for your next dose, skip the missed dose. Go back to your regular dosing schedule. Do not take 2 doses at once.

Important safety information:

  • Zonisamide may cause dizziness, drowsiness, or vision changes. These effects may be worse if you take it with alcohol or certain medicines. Use Zonisamide with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Zonisamide may reduce sweating, which could increase the risk of heat stroke, especially in children. The risk is greater in hot weather and/or during vigorous exercise. Drink plenty of fluids. Dress lightly while in hot climates or when exercising. Check carefully for signs of decreased sweating. If this occurs, promptly seek cooler or air-conditioned shelter and/or stop exercising. Seek medical attention right away if you have an unexplained fever, or if you have mental or mood changes, headache, or dizziness.
  • Zonisamide may cause high blood acid levels (metabolic acidosis). The risk may be greater in children and in patients with kidney problems, severe breathing problems, or diarrhea. It may also be greater in patients who are taking certain other medicines (eg, acetazolamide), will be having surgery, or are on a ketogenic diet. Over a period of time, metabolic acidosis may cause kidney problems, bone problems, or decreased growth in children. Contact your doctor immediately if you experience fast breathing, unusual weakness or fatigue, sluggishness, fainting, persistent loss of appetite, or irregular heartbeat.
  • Contact your doctor at once if your seizures worsen or if you develop a skin rash.
  • Tell your doctor or dentist that you take Zonisamide before you receive any medical or dental care, emergency care, or surgery.
  • Carry an ID card at all times that says you take Zonisamide .
  • This product may contain tartrazine dye (FD&C Yellow No. 5). This may cause an allergic reaction in some patients. If you have ever had an allergic reaction to tartrazine, ask your pharmacist if your product has tartrazine in it.
  • Women who take Zonisamide should use effective birth control while using Zonisamide .
  • Lab tests, including kidney function tests or blood bicarbonate levels, may be performed while you use Zonisamide . These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • Zonisamide should be used with extreme caution in CHILDREN younger than 16 years old; safety and effectiveness in these children have not been confirmed. CHILDREN may be at a higher risk of heatstroke and metabolic acidosis.
  • PREGNANCY AND BREAST-FEEDING: Zonisamide may cause harm to the fetus. Do not become pregnant while you are using it. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Zonisamide while you are pregnant. It is not known if Zonisamide is found in breast milk. If you are or will be breast-feeding while you use Zonisamide , check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Zonisamide :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Abnormal skin sensations; diarrhea; dizziness; drowsiness; flu-like symptoms; headache; irritability; loss of appetite; nausea; stomach upset; tiredness; trouble sleeping.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bone pain; changes in the amount of urine produced; confusion; dark or bloody urine; decreased sweating; double vision or other vision problems; fainting; fast breathing; fast, slow, or irregular heartbeat; fever, chills, or sore throat; loss of coordination; memory problems; mental or mood changes (eg, agitation, depression); mouth sores; painful urination; persistent loss of appetite; red, swollen, blistered, or peeling skin; severe muscle pain or weakness; severe or persistent drowsiness; sluggishness; sudden stomach or back pain; suicidal thoughts or actions; swelling of the hands, ankles, or feet; tremor; trouble speaking or other speech problems; trouble thinking or concentrating; unusual bruising or bleeding; unusual eye movements; unusual or disturbing thoughts; unusual tiredness or weakness.

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