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Zafirlukast 10mg Tablet – Generic Accolate

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Accolate is used for:

Prevention and long-termtreatment of asthma
in patients 5 years old and older. It should not be used to treat acute
asthma attacks. The medicine may be used for other conditions as determined by
your doctor.

Accolate is a leukotriene receptor antagonist. It works by
blocking the action of certain chemicals that are responsible for some forms of

Do NOT use Accolate if:

  • you areallergic
    to any ingredient in Accolate


Before using Accolate :

Some medical conditions may interact with Accolate . Tell
your doctor or pharmacist if you have any medical conditions, especially if any
of the following apply to you:

  • if you are pregnant, planning to
    become pregnant, or are breast-feeding
  • if you are taking any
    prescription or nonprescription medicine, herbal preparation, or dietary
  • if youhave
    to medicines, foods, or other substances
  • if you have a history of liver
  • if you have a history of mental
    or mood problems (eg, depression) or suicidal thoughts or actions
  • if you are taking a steroid (eg,

Some MEDICINES MAY INTERACT with Accolate . Tell your
health care provider
if you are taking any other medicines, especially any of the following:

  • Anticoagulants (eg, warfarin)
    because the risk of bleeding may be increased by Accolate
  • Erythromycin because it may
    decrease Accolate ‘s effectiveness
  • Certain anticonvulsants (eg,
    carbamazepine, phenobarbital, phenytoin), calcium channel blockers (eg,
    amlodipine), cisapride, cyclosporine, theophylline, or tolbutamide because
    the risk of their side effects may be increased by Accolate

This may not be a complete list of all interactions that may
occur. Ask your health care provider if Accolate may interact with other
medicines that you take. Check with your health care provider before you start,
stop, or change the dose of any medicine.

How to use Accolate :

Use Accolate as directed by your doctor. Check the label on
the medicine for exact dosing instructions.

  • Take Accolate by mouth on an
    empty stomach at least 1 hour before or 2 hours aftereating.
  • Taking Accolate at the same time
    each day will help you remember to take it.
  • Take Accolate on a regular
    schedule to get the most benefit from it.
  • Continue to take Accolate even if
    you feel well. Do not miss any doses.
  • If you miss a dose of Accolate ,
    take it as soon as possible. If it is almost time for your next dose, skip
    the missed dose and go back to your regular dosing schedule. Do not take 2
    doses at once.

Ask your health care provider any questions you may have
about how to use Accolate .

Important safety information:

  • Accolate will not stop an asthma
    attack once one has started. If you are also using a bronchodilator inhaler,
    be sure to always carry the bronchodilator inhaler with you to use during
    asthma attacks.
  • If your symptoms do not get
    better or if they get worse, check with your doctor.
  • Do not decrease your dose or stop
    using Accolate or other asthma medicines without first checking with your
  • Accolate may rarely cause severe
    and sometimes fatal liver problems. Tell your doctor right away if you
    experience symptoms of liver problems (eg, yellowing of the skin or eyes,
    dark urine, flu-like symptoms, itching, loss of appetite, persistent nausea
    pain, unusual tiredness).
  • If your doctor tells you that you
    have had liver damage because of use of Accolate , do not take Accolate
  • Some patients taking Accolate
    have developed mental or mood changes, including suicidal thoughts or
    actions. Contact your doctor immediately if you experience symptoms such as
    agitation, aggression, hostility, anxiety, depression, strange dreams,
    trouble sleeping, sleepwalking, tremor, hallucinations, restlessness,
    irritability, or any unusual change in mood or behavior. Contact your doctor
    immediately if any signs of suicidal thoughts or actions occur.
  • Lab tests, including liver
    function, may be performed while you use Accolate . These tests may be used
    to monitor your condition or check for side effects. Be sure to keep all
    doctor and lab appointments.
  • Use Accolate with caution in the
    ELDERLY; they may be more sensitive to its effects.
  • Accolate should not be used in
    younger than 5 years old; safety and effectiveness in these
    children have not been confirmed.
    you become pregnant, contact your doctor. You will need to discuss the
    benefits and risks of using Accolate while you are pregnant. Accolate is
    found in breast milk. Do not breast-feed while taking Accolate .

Possible side effects of Accolate :

All medicines may cause side effects, but many people have
no, or minor, side effects. Check with your doctor if any
of these most COMMON side effects persist or become bothersome:

Diarrhea; headache; nausea.

Seek medical attention right away if any of these SEVERE
side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty
breathing; tightness in the chest; swelling of the mouth, face, lips, or
tongue, unusual hoarseness); burning, numbness, or tingling of the skin,
hands, or feet; chest pain; fever, chills, or persistent
sore throat; joint or muscle aches and pains; mental or mood changes (eg,
agitation, aggression, hostility, anxiety, depression, severe or persistent
trouble sleeping, strange dreams, sleepwalking, tremor, hallucinations,
restlessness, irritability, any unusual change in behavior); new or worsening
shortness of breath or other breathing problems; suicidal thoughts or actions;
symptoms of liver problems (eg, yellowing of the skin or eyes, dark urine,
flu-like symptoms, itching, loss of appetite, persistent nausea or stomach
pain, unusual tiredness); unusual bruising or bleeding.

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