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Venlafaxine HCl 25mg Tablets – Generic Effexor

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Antidepressants may increase the risk of suicidal thoughts
or actions in children, teenagers, and young adults. However, depression and
certain other mental problems may also increase the risk of suicide. Talk with
the patient’sdoctor
to be sure that the benefits of using Venlafaxine outweigh the risks.

and caregivers must closely watch patients who take Venlafaxine . It is
important to keep in close contact with the patient’s doctor. Tell the doctor
right away if the patient has symptoms like worsened depression, suicidal
thoughts, or changes in behavior. Discuss any questions with the patient’s

Venlafaxine is used for:

Treating depression. It may also be used for other conditions
as determined by your doctor.

Venlafaxine is a serotonin-norepinephrine reuptake inhibitor
(SNRI). It works by restoring the balance of certain natural substances in the
brain (serotonin and norepinephrine), which helps to improve certain mood

Do NOT use Venlafaxine if:

  • you areallergic
    to any ingredient in Venlafaxine
  • you are taking or have taken a
    monoamine oxidase inhibitor (MAOI) (eg, phenelzine), selegiline, or St.
    John’s wort within the last 14 days
  • you are taking a fenfluramine
    derivative (eg, dexfenfluramine), methylene blue, sibutramine, nefazodone,
    or tryptophan

Before using Venlafaxine :

Some medical conditions may interact with Venlafaxine . Tell
your doctor or pharmacist if you have any medical conditions, especially if any
of the following apply to you:

  • if you are pregnant, planning to
    become pregnant, or are breast-feeding
  • if you are taking any
    prescription or nonprescription medicine, herbal preparation, or dietary
  • if you have allergies to
    or other substances
  • if you or afamily
    member has a history of bipolar disorder (manic-depression), other mental or
    mood problems, suicidal thoughts or attempts, or alcohol or substance abuse
  • if you have a history of
    (eg, heart failure, irregular heartbeat), abnormal
    electrocardiograms (ECGs), a recent heart attack, high blood pressure,
    overactive thyroid, liver problems, lung problems, kidney problems, stomach
    or bowel bleeding, blood or bleeding problems, increased eye pressure (eg,
    glaucoma), nervous system problems, or metabolism problems
  • if you are dehydrated, have low
    blood sodium levels, or drink alcohol
  • if you will be having
    electroconvulsive therapy (ECT)

Some MEDICINES MAY INTERACT with Venlafaxine . Tell your
health care provider if you are taking any other medicines, especially any of
the following:

  • Certain diet medicines (eg,
    phentermine, fenfluramine), linezolid, lithium, MAOIs (eg, phenelzine),
    methylene blue, metoclopramide, nefazodone, rasagiline, selective serotonin
    reuptake inhibitors (SSRIs) (eg, fluoxetine), selegiline, serotonin 5-HT1
    receptor agonists (eg, sumatriptan), sibutramine, SNRIs (eg, duloxetine),St.
    John’s wort, tramadol, trazodone, tricyclic antidepressants (eg,
    amitriptyline), or tryptophan because severe side effects, such as a
    reaction that may include fever, rigid muscles, blood pressure changes,
    mental changes, confusion, irritability, agitation, delirium, and coma, may
  • Anticoagulants (eg, warfarin),aspirin,
    or nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, ibuprofen) because the
    risk of bleeding, including stomach bleeding, may be increased
  • Diuretics (eg, furosemide,
    hydrochlorothiazide) because the risk of low blood sodium levels may be
  • Azole antifungals (eg,
    ketoconazole) or cimetidine because they may increase the risk of
    Venlafaxine ‘s side effects
  • Cyproheptadine because it may
    decrease Venlafaxine ‘s effectiveness
  • Aripiprazole, haloperidol,
    phenothiazines (eg, chlorpromazine, thioridazine), or risperidone because
    the risk of their side effects may be increased by Venlafaxine

How to use Venlafaxine :

Use Venlafaxine as directed by your doctor. Check the label
on the medicine for exact dosing instructions.

  • Venlafaxine comes with an extra
    patient information sheet called a Medication Guide. Read it carefully. Read
    it again each time you get Venlafaxine refilled.
  • Take Venlafaxine by mouth with
  • Venlafaxine works best if it is
    taken at the same time each day.
  • Continue to take Venlafaxine even
    if you feel well. Do not miss any doses.
  • Do not suddenly stop taking
    Venlafaxine without checking with your doctor. Side effects may occur. They
    may include mental or mood changes, numbness or tingling of the skin,
    dizziness, drowsiness, confusion, headache, increased sweating, loss of
    coordination or balance, flu-like symptoms, nausea, ringing in the ears,
    seizures, tremor, trouble sleeping, or unusual tiredness. You will be
    closely monitored when you start Venlafaxine and whenever a change in dose
    is made.
  • If you miss a dose of Venlafaxine
    , take it as soon as possible. If it is almost time for your next dose, skip
    the missed dose and go back to your regular dosing schedule. Do not take 2
    doses at once.

Important safety information:

  • Venlafaxine may cause drowsiness,
    dizziness, or blurred vision. These effects may be worse if you take it with
    alcohol or certain medicines. Use Venlafaxine with caution. Do not drive or
    perform other possibly unsafe tasks until you know how you react to it.
  • Do not drink alcohol or use
    medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while
    you are using Venlafaxine without checking with your doctor; it may add to
    their effects. Ask your pharmacist if you have questions about which
    medicines may cause drowsiness.
  • Several weeks may pass before
    your symptoms improve. Do NOT take more than the recommended dose or use for
    longer than prescribed without checking with your doctor.
  • Children,
    teenagers, and young adults who take Venlafaxine may be at increased risk
    for suicidal thoughts or actions. Watch all patients who take Venlafaxine
    closely. Contact the doctor at once if new, worsened, or sudden symptoms
    such as depressed mood; anxious, restless, or irritable behavior; panic
    attacks; or any unusual change in mood or behavior occur. Contact the doctor
    right away if any signs of suicidal thoughts or actions occur.
  • Serotonin syndrome is a possibly
    fatal syndrome that can be caused by Venlafaxine . Your risk may be greater
    if you take Venlafaxine with certain other medicines (eg, “triptans,”
    MAOIs, SSRIs). Symptoms may include agitation; confusion; hallucinations;
    coma; fever; fast or irregular heartbeat; tremor; excessive sweating; and
    nausea, vomiting, or diarrhea. Contact your doctor at once if you have any
    of these symptoms.
  • Neuroleptic malignant syndrome (NMS)
    is a possibly fatal syndrome that can be caused by Venlafaxine . Symptoms
    may include fever; stiff muscles; confusion; abnormal thinking; fast or
    irregular heartbeat; and sweating. Contact your doctor at once if you have
    any of these symptoms.
  • If your doctor tells you to stop
    taking Venlafaxine , you will need to wait for a period of time before
    beginning to take certain other medicines (eg, MAOIs, nefazodone,
    your doctor
    when you should start to take your new medicines
    after you have stopped taking Venlafaxine .
  • Venlafaxine may rarely cause a
    prolonged, painful erection. This could happen even when you are not having
    sex. If this is not treated right away, it could lead to permanent sexual
    problems such as impotence. Contact your doctor right away if this happens.
  • Lab tests, including blood
    pressure and blood cholesterol levels, may be performed while you use
    Venlafaxine . These tests may be used to monitor your condition or check for
    side effects. Be sure to keep all doctor and lab appointments.
  • Use Venlafaxine with caution in
    the ELDERLY; they may be more sensitive to its effects, especially low blood
    sodium levels.
  • Caution is advised when using
    Venlafaxine in CHILDREN; they may be more sensitive to its effects,
    especially increased risk of suicidal thoughts or actions.
  • Venlafaxine should be used with
    extreme caution in CHILDREN; safety and effectiveness in children have not
    been confirmed.
  • Venlafaxine may cause weight
    changes and growth changes. CHILDREN and teenagers may need regular weight
    and growth checks while they take Venlafaxine .
    Venlafaxine may cause harm to the fetus if it is used during the last 3
    months of pregnancy. If you become pregnant, contact your doctor. You will
    need to discuss the benefits and risks of using Venlafaxine while you are
    pregnant. Venlafaxine is found in breast milk. Do not breast-feed while
    taking Venlafaxine .

Possible side effects of Venlafaxine :

All medicines may cause side effects, but many people have
no, or minor, side effects. Check with your doctor if any
of these most COMMON side effects persist or become bothersome:

Anxiety; blurred vision; changes in taste; constipation;
decreased sexual desire or ability; dizziness; drowsiness; dry mouth;
flushing; headache; increased sweating; loss of appetite; nausea; nervousness;
stomach upset; trouble sleeping; vomiting; weakness; weight loss; yawning.

Seek medical
right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty
breathing; tightness in the chest; swelling of the mouth, face, lips, or
tongue); bizarre behavior; blood in the stool;chest
or discomfort; confusion; decreased concentration; decreased
coordination; decreased urination; fainting; fast or irregular heartbeat;
fever, chills, or sore throat; hallucinations; memory problems; new or
worsening aggressiveness, agitation, hostility, impulsiveness, inability to
sit still, irritability, panic attacks, or restlessness; persistent or severe
ringing in the ears; red, swollen, blistered, or peeling skin; seizures;
severe or persistent anxiety, nervousness, or trouble sleeping; severe or
persistent cough; severe or persistent headache, dizziness, stomach pain, or
weakness; shortness of breath; significant weight loss; suicidal thoughts or
attempts; tremor; trouble concentrating; unsteadiness or loss of coordination;
unusual bruising or bleeding; unusual or severe mental or mood changes;
unusual weakness; vision problems; worsening of depression.

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