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Tolmetin 600mg Tablet – Generic Tolectin

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Tolmetin is a nonsteroidal anti-inflammatory drug (NSAID).
It may cause an increased risk of serious and sometimes fatal heart and

problems (eg, heart attack, stroke). The risk may be greater if you already
have heart problems or if you take Tolmetin for a long time. Do not use
Tolmetin right before or after bypass heart surgery.

Tolmetin may cause an increased risk of serious and
sometimes fatal stomach ulcers and bleeding. Elderly patients may be at
greater risk. This may occur without warning signs.

Tolmetin is used for:

rheumatoid arthritis
, osteoarthritis, or juvenile arthritis. It may
also be used for other conditions as determined by your doctor.

Tolmetin is an NSAID. Exactly how it works is not known. It
may block certain substances in the body that are linked
to inflammation. NSAIDs treat the symptoms of pain and inflammation. They do not
treat the disease that causes those symptoms.

Do NOT use Tolmetin if:

  • you are allergic to any
    ingredient in Tolmetin

  • you have had a severe allergic
    reaction (eg, severe rash, hives, trouble breathing, growths in the nose,
    dizziness) to aspirin or a nonsteroidal anti-inflammatory drug (NSAID) (eg,
    ibuprofen, celecoxib)

  • you have recently had or will be
    having bypass heart surgery

  • you are in the last 3 months of

Before using Tolmetin :

Some medical conditions may interact with Tolmetin . Tell
your doctor or pharmacist if you have any medical conditions, especially if any
of the following apply to you:

  • if you are pregnant, planning to
    become pregnant, or are breast-feeding

  • if you are taking any
    prescription or nonprescription medicine, herbal preparation, or dietary

  • if you have allergies to
    medicines, foods,
    or other substances

  • if you have a history of kidney
    or liver disease, diabetes, or stomach or bowel problems (eg, bleeding,
    perforation, ulcers)

  • if you have a history of swelling
    or fluid buildup, asthma, growths in the nose (nasal polyps), or mouth

  • if you have high blood

    blood disorders, bleeding or clotting problems, heart problems (eg, heart
    failure), or blood vessel disease, or if you are at risk for any of these

  • if you have poor health,
    dehydration or low fluid volume, or low blood sodium levels, you drink
    alcohol, or you have a history of alcohol abuse

Some MEDICINES MAY INTERACT with Tolmetin . Tell your health
care provider if you are taking any other medicines, especially any of the

  • Anticoagulants (eg, warfarin),
    corticosteroids (eg, prednisone), heparin, salicylates (eg, aspirin), or
    selective serotonin reuptake inhibitors (SSRIs) (eg, fluoxetine) because the
    risk of stomach bleeding may be increased

  • Probenecid because it may
    increase the risk of Tolmetin ‘s side effects

  • Cyclosporine, lithium,
    methotrexate, or quinolones (eg, ciprofloxacin) because the risk of their
    side effects may be increased by Tolmetin

  • Angiotensin-converting enzyme
    (ACE) inhibitors (eg, enalapril), beta-blockers (eg, propranolol), or
    diuretics (eg, furosemide, hydrochlorothiazide) because their effectiveness
    may be decreased by Tolmetin

How to use Tolmetin :

Use Tolmetin as directed by your doctor. Check the label on
the medicine for exact dosing instructions.

  • Tolmetin comes with an extra
    patient information sheet called a Medication Guide. Read it carefully. Read
    it again each time you get Tolmetin refilled.

  • Take Tolmetin by mouth. It may be
    taken with food
    if it upsets your stomach. Taking it with food may not lower the risk of
    stomach or bowel problems (eg, bleeding, ulcers). Talk with your doctor or
    pharmacist if you have persistent stomach upset.

  • If Tolmetin upsets your stomach,
    you may take it with an antacid. Do not take it with sodium bicarbonate.

  • Take Tolmetin with a full glass
    of water (8 oz/240 mL) as directed by your doctor.

  • If you miss a dose of Tolmetin
    and you are taking it regularly, take it as soon as possible. If it is
    almost time for your next dose, skip the missed dose. Go back to your
    regular dosing schedule. Do not take 2 doses at once.

Important safety information:

  • Tolmetin may cause dizziness or
    drowsiness. These effects may be worse if you take it with alcohol or
    certain medicines. Use Tolmetin with caution. Do not drive or perform other
    possibly unsafe tasks until you know how you react to it.

  • Serious stomach ulcers or
    bleeding can occur with the use of Tolmetin . Taking it in high doses or for
    a long time, smoking, or drinking alcohol increases the risk of these side
    effects. Taking Tolmetin with food will NOT reduce the risk of these
    effects. Contact your doctor or emergency
    at once if you develop severe stomach or back pain; black,
    tarry stools; vomit that looks like blood or coffee grounds; or unusual
    weight gain or swelling.

  • Do NOT take more than the
    recommended dose or use for longer than prescribed without checking with
    your doctor.

  • Tolmetin is an NSAID. Before you
    start any new medicine, check the label to see if it has an NSAID (eg,
    ibuprofen) in it too. If it does or if you are not sure, check with your
    doctor or pharmacist.

  • Do not take aspirin while you are
    using Tolmetin unless your doctor tells you to.

  • Tolmetin may interfere with
    certain lab tests. Be sure your doctor and lab personnel know that you take
    Tolmetin .

  • Lab tests, including kidney
    function, complete blood cell counts, and blood pressure, may be performed
    while you use Tolmetin . These tests may be used to monitor your condition
    or check for side effects. Be sure to keep all doctor and lab appointments.

  • Use Tolmetin with caution in the
    ELDERLY; they may be more sensitive to its effects, especially stomach
    bleeding and kidney problems.

  • Tolmetin should be used with
    extreme caution in CHILDREN younger than 2 years old;
    safety and effectiveness in these children have not been confirmed.

    Tolmetin may cause harm to the fetus. Do not use it during the last 3 months
    of pregnancy. If you think you may be pregnant, contact your doctor. You
    will need to discuss the benefits and risks of using Tolmetin while you are
    pregnant. Tolmetin is found in breast milk. Do not breast-feed while taking
    Tolmetin .

Possible side effects of Tolmetin :

All medicines may cause side effects, but many people have
no, or minor, side effects. Check with your doctor if any
of these most COMMON side effects persist or become bothersome:

Constipation; diarrhea; dizziness; gas; headache;
heartburn; nausea; stomach upset; weakness.

Seek medical attention right away if any of these SEVERE
side effects occur:

Severe allergic reactions (rash; hives; itching; trouble
breathing; tightness in the chest; swelling of the mouth, face, lips, or
tongue); bloody or black, tarry stools; change in the amount of urine
produced; chest pain; confusion; dark urine; depression; fainting; fast or
irregular heartbeat; fever, chills, or persistent sore throat; mental or mood
changes; numbness of an arm or leg; one-sided weakness; red, swollen,
blistered, or peeling skin;
ringing in the ears; seizures; severe headache or dizziness; severe or
persistent stomach pain or nausea; severe vomiting; shortness of breath;
sudden or unexplained weight gain; swelling of hands, legs, or feet; unusual
bruising or bleeding; unusual joint or muscle pain; unusual tiredness or
weakness; vision or speech changes; vomit that looks like coffee grounds;
yellowing of the skin or eyes.

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