Quinapril HCl 10mg Tablets – Generic Accupril
Actual product appearance may differ slightly.
Quinapril can cause injury and possibly death to the fetus
when used after the third month of pregnancy. If you think you may be pregnant,
contact your doctor right away.
Quinapril is used for:
high blood pressure alone or with other medicines. It is used along
with other medicines to manage heart failure. It may also be used for other
conditions as determined by your doctor.
Quinapril is an angiotensin-converting enzyme (ACE)
inhibitor. It works by relaxing blood vessels. This helps to lower blood
Do NOT use Quinapril if:
- you are allergic
to any ingredient in Quinapril
- you are in the second or third
trimester of pregnancy
- you have a history of angioedema
(swelling of the face, lips, throat, or tongue) caused by treatment with an
Before using Quinapril :
Some medical conditions may interact with Quinapril . Tell
your doctor or pharmacist if you have any medical conditions, especially if any
of the following apply to you:
- if you are pregnant, planning to
become pregnant, or are breast-feeding
- if you are taking any
prescription or nonprescription medicine, herbal preparation, or dietary
- if you have
allergies to medicines, foods, or other substances
- if you are able to become
- if you have a history of
diabetes, heart problems (eg, heart failure, aortic stenosis), blood
vessel problems, blood flow problems, bone marrow problems, or
kidney or liver problems
- if you have a history of stroke, recent
heart attack, or kidney transplant
- if you have an autoimmune disease
arthritis, lupus, scleroderma)
- if you are dehydrated or have low
- if you have high blood potassium
levels, low blood sodium levels, or are on a low-salt (sodium) diet
- if you are scheduled to have
major surgery or are on dialysis
Some MEDICINES MAY INTERACT with Quinapril . Tell your health
care provider if you are taking any other medicines, especially any of the
- Clozapine, cyclosporine, dextran
sulfate, HMG-CoA reductase inhibitors (eg, simvastatin), mannitol,
nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, ibuprofen, indomethacin),
pergolide, phenothiazines (eg, thioridazine), potassium preparations,
potassium-sparing diuretics (eg, spironolactone), thiazide diuretics (eg,
hydrochlorothiazide), or trimethoprim because side effects, such as low
blood pressure or increased potassium levels leading to heart attack, may
- Gold-containing medicines (eg,
auranofin, sodium aurothiomalate) because flushing, nausea, vomiting, and
low blood pressure
- Clozapine, iron salts (eg,
ferrous sulfate), lithium, NSAIDs (eg, ibuprofen, indomethacin), potassium
preparations, potassium-sparing diuretics (eg, spironolactone),
sulfonylureas (eg, glipizide), thiazide diuretics (eg, hydrochlorothiazide),
or thiopurines (eg, azathioprine) because the risk of their side effects may
be increased by Quinapril
How to use Quinapril :
Use Quinapril as directed by your doctor. Check the label on
the medicine for exact dosing instructions.
- Take Quinapril by mouth on an
empty stomach at least 1 hour before or 2 hours after eating, or with a
light meal. High-fat meals, however, may decrease the
absorption of the medicine into your bloodstream.
- If you are taking a tetracycline
(eg, doxycycline) or fluoroquinolone (eg, ciprofloxacin), take it at least 3
hours apart from Quinapril . This product contains magnesium, which can
interfere with absorption of these antibiotics.
- If you miss a dose of Quinapril ,
take it as soon as possible. If it is almost time for your next dose, skip
the missed dose and go back to your regular dosing schedule. Do not take 2
doses at once.
Important safety information:
- Quinapril may cause dizziness,
lightheadedness, or fainting. These effects may be worse if you take it with
alcohol or certain medicines. Use Quinapril with caution. Do not drive or
perform other possibly unsafe tasks until you know how you react to it.
- Quinapril may cause dizziness,
lightheadedness, or fainting; alcohol, hot weather, exercise, or fever may
increase these effects. To prevent them, sit up or stand slowly, especially
in the morning. Sit or lie down at the first sign of any of these effects.
- Quinapril may cause a serious
side effect called angioedema. Contact your doctor at once if you develop
swelling of the hands, face, lips, eyes, throat, or tongue; difficulty
swallowing or breathing; or hoarseness.
- Patients who take medicine for
high blood pressure often feel tired or run down for a few weeks after
starting treatment. Be sure to take your medicine even if you may not feel
“normal.” Tell your doctor if you develop any new symptoms.
- Quinapril has magnesium in it.
Before you start any new medicine, check the label to see if it has
magnesium in it too. If it does or if you are not sure, check with your
doctor or pharmacist.
- Quinapril may cause you to become
sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you
know how you react to Quinapril . Use a sunscreen or wear protective
clothing if you must be outside for more than a short time.
- Check with your doctor before you
use a salt substitute or a product that has potassium in it.
- Dehydration, excessive sweating,
vomiting, or diarrhea may lead to a fall in blood pressure. Contact your
health care provider at once if any of these occur.
- Quinapril may lower the ability
of your body to fight infection. Avoid contact with people who have colds or
infections. Tell your doctor if you notice signs of infection like fever,
sore throat, rash, or chills.
- Quinapril may not work as well in
black patients. They may also be at greater risk of side effects. Contact
your doctor if your symptoms do not improve or if they become worse.
- If you have high blood pressure,
do not use nonprescription products that contain stimulants. These products
may include diet pills or cold medicines. Contact your doctor if you have
any questions or concerns.
- Tell your doctor or dentist that
you take Quinapril before you receive any medical or dental
care, emergency care, or surgery.
- Diabetes patients – Quinapril may
affect your blood sugar. Check blood sugar levels closely. Ask your doctor
before you change the dose of your diabetes medicine.
- Lab tests, including blood
pressure, blood electrolyte levels, heart function, or kidney or liver
function may be performed while you use Quinapril . These tests may be used
to monitor your condition or check for side effects. Be sure to keep all
doctor and lab appointments.
- Use Quinapril with caution in the
ELDERLY; they may be more sensitive to its effects.
- Quinapril should be used with
extreme caution in CHILDREN; safety and effectiveness in children have not
- PREGNANCY and BREAST-FEEDING:
Quinapril may cause birth defects and fetal or newborn death if you take it
while you are pregnant. Do not become pregnant while you take it. If you
think you may be pregnant, contact your doctor right away. Quinapril is
found in breast milk. If you are or will be breast-feeding while you use
Quinapril , check with your doctor. Discuss any possible risks to your baby.
Possible side effects of Quinapril :
All medicines may cause side effects, but many people have
no, or minor, side effects. Check with your doctor if any
of these most COMMON side effects persist or become bothersome:
Cough; diarrhea; dizziness; headache; lightheadedness;
nausea; tiredness; vomiting.
Seek medical attention right away if any of these SEVERE
side effects occur:
Severe allergic reactions (rash; hives; itching; difficulty
breathing; tightness in the chest; swelling of the mouth, face, lips, or
tongue; unusual hoarseness); chest
pain; fainting; infection (sore throat, fever); numbness of arm or
leg; shortness of breath; slow, fast, or irregular heartbeat; sudden, severe
headache or vomiting; unusual bleeding or bruising; unusual stomach pain;
unusual tiredness or weakness; yellowing of the skin or eyes.