Factive is used to treat certain infections such as pneumonia or bronchitis. Factive is in a class of antibiotics called fluoroquinolones. It works by killing bacteria that cause infections. Antibiotics do not work for colds, flu, or other viral infections.
Gemifloxacin comes as a tablet to take by mouth. It is usually taken with or without food once a day for 5 or 7 days. The length of your treatment depends on the type of infection you have. Your doctor will tell you how long to take gemifloxacin. Take gemifloxacin at around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take gemifloxacin exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor. Swallow the tablets whole with plenty of water; do not split, chew, or crush them.
You should begin feeling better during the first few days of treatment with gemifloxacin. If your symptoms do not improve or if they get worse, call your doctor. Take gemifloxacin until you finish the prescription, even if you feel better. Do not stop taking gemifloxacin unless you experience the symptoms of tendinitis or tendon rupture described in the IMPORTANT WARNING section or the symptoms of allergic reaction described in the SIDE EFFECTS section. If you stop taking gemifloxacin too soon or skip doses, your infection may not be completely treated and the bacteria may become resistant to antibiotics.
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
Before taking gemifloxacin,
- tell your doctor and pharmacist if you are allergic or have had a severe reaction to gemifloxacin or any other quinolone or fluoroquinolone antibiotics such as ciprofloxacin (Cipro), gatifloxacin (Tequin) (not available in the US), levofloxacin (Levaquin), lomefloxacin (Maxaquin) (not available in the US), moxifloxacin (Avelox), nalidixic acid (NegGram), norfloxacin (Noroxin), ofloxacin (Floxin), and sparfloxacin (Zagam) (not available in the US); any other medications; or if you are allergic to any of the ingredients in gemifloxacin. Ask your pharmacist or check the Medication Guide for a list of the ingredients.
- tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention the medications listed in the IMPORTANT WARNING section and any of the following: anticoagulants ('blood thinners') such as warfarin (Coumadin, Jantoven); certain antidepressants; antipsychotics (medications to treat mental illness); cisapride (Propulsid) (not available in the US); diuretics ('water pills'); erythromycin (E.E.S., E-mycin, Erythrocin, others); hormone replacement therapy; certain medications for irregular heartbeat such as amiodarone (Cordarone), procainamide (Procanbid), quinidine, and sotalol (Betapace, Betapace AF, Sorine); nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen (Advil, Motrin, others) and naproxen (Aleve, Naprosyn, others); or probenecid (in Col-Probenecid, Probalan). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
- if you are taking antacids containing aluminum hydroxide or magnesium hydroxide (Maalox, Mylanta, Tums, others); didanosine (Videx); sucralfate (Carafate); or vitamin or mineral supplements that contain iron, magnesium, or zinc, take these medications 3 hours before or 2 hours after you take gemifloxacin.
- tell your doctor if you or anyone in your family has or has ever had a prolonged QT interval (a rare heart problem that may cause irregular heartbeat, fainting, or sudden death) or an irregular heartbeat, and if you have or have ever had nerve problems, a low level of potassium or magnesium in your blood, seizures, cerebral arteriosclerosis (narrowing of blood vessels in or near the brain that can lead to stroke or mini-stroke), a slow heartbeat, chest pain, or liver disease.
- tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking gemifloxacin, call your doctor.
- you should know that gemifloxacin may cause confusion, dizziness, lightheadedness, and tiredness. Do not drive a car, operate machinery, or participate in activities requiring alertness or coordination until you know how this medication affects you.
- plan to avoid unnecessary or prolonged exposure to sunlight or ultraviolet light (sunlamps or tanning beds) and wear protective clothing, sunglasses, and sunscreen. Gemifloxacin may make your skin sensitive to sunlight or ultraviolet light. If your skin becomes reddened, swollen, or blistered, like a bad sunburn, call your doctor.
Make sure you drink plenty of water or other fluids every day while you are taking gemifloxacin.
Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take more than one dose of gemifloxacin in one day.
Gemifloxacin may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
- stomach pain
Some side effects can be serious. If you experience any of these symptoms, or those mentioned in the IMPORTANT WARNING section, stop taking gemifloxacin and call your doctor immediately:
- severe diarrhea (watery or bloody stools) that may occur with or without fever and stomach cramps (may occur up to 2 months or more after your treatment)
- difficulty breathing or swallowing
- swelling of the face, tongue, or lips
- hoarseness or throat tightness
- rapid heartbeat
- yellowing of the skin or eyes
- hallucinations (seeing things or hearing voices that do not exist)
- not trusting others or feeling that others want to hurt you
- thoughts about dying or killing yourself
- difficulty falling asleep or staying asleep
- uncontrollable shaking of a part of the body
- pain, burning, tingling, numbness, and/or weakness in a part of the body
Gemifloxacin may cause problems with bones, joints, and tissues around joints in children. Gemifloxacin should not be given to children younger than 18 years of age. Talk to your child's doctor about the risks of giving gemifloxacin to your child. Gemifloxacin may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from light and excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.
In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.
Keep all appointments with your doctor and the laboratory. Your doctor may order certain lab tests to check your body's response to gemifloxacin. Do not let anyone else take your medication. Your prescription is probably not refillable. If you still have symptoms of infection after you finish taking gemifloxacin, call your doctor. It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.