What is fluorouracil skin cream or solution?
FLUOROURACIL, 5-FU is a topical chemotherapy agent used for treating certain skin problems, including skin cancer and skin conditions that could become cancer. Fluorouracil interferes with the growth of abnormal cells, which are eventually destroyed. Generic fluorouracil skin cream or solution are not yet available.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
•inflammation or open sores at the treatment site
•recent or current radiation therapy
•an unusual or allergic reaction to fluorouracil, other chemotherapy, other medicines, foods, dyes, or preservatives
•pregnant or trying to get pregnant
How should I use this medicine?
Fluorouracil cream or solution is only for use on the skin. Follow the directions on the prescription label. Wash hands before use. Wash affected area and gently pat dry. To apply the cream or solution use a cotton-tipped applicator, or use gloves if applying with fingertips. If applied with unprotected fingertips, it is very important to wash your hands well after you apply this medicine. Avoid application to eyes, nose, or mouth. Apply enough cream or solution to cover the affected area. You can cover the area with a light gauze dressing. Finish the full course prescribed by your doctor or health care professional, even if you think your condition is better. Do not stop taking except on your prescriber's advice.
What if I miss a dose?
If you miss a dose, apply it as soon as you can. If it is almost time for your next dose, only use that dose. Do not apply extra doses. Contact your prescriber or health care professional if you miss more than one dose.
What drug(s) may interact with fluorouracil?
Tell your prescriber or health care professional about other skin products that you are using, including non-prescription skin products. Check with your prescriber or health care professional before stopping or starting any of your medicines.
What side effects may I notice from using fluorouracil?
Side effects that you should report to your prescriber or health care professional as soon as possible:
•severe redness and swelling of normal skin
Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome):
•dark colored skin
•eye irritation including burning, itching, sensitivity, stinging, or watering
•increased sensitivity of the skin to sun and ultraviolet light
•pain and burning of the affected area
•scaling or swelling of the affected area
•skin rash, itching of the affected area
What should I watch for while taking fluorouracil?
Visit your prescriber or health care professional for checks on your progress. You will need to use the cream or solution for between 2 to 6 weeks (this may be longer depending on the condition being treated). You may not see full healing for another 1 to 2 months after you stop using fluorouracil.
If you apply fluorouracil to your face, do not get any in the eyes, nose or mouth. Always wash your hands thoroughly after use to avoid getting any fluorouracil in your eyes, nose, mouth or other sensitive areas. Fluorouracil could cause irritation and sores if it comes in contact with these areas. It is very important to wash your hands well after applying fluorouracil, even if you used gloves, to make sure the cream or solution does not come into contact with unaffected skin.
A moisturizer or sunscreen may be applied 2 hours after applying fluorouracil cream. Do not use any other skin products including creams, lotions, medications or cosmetics, unless instructed by your health care provider.
Treated areas of skin can look unsightly during and for several weeks after treatment with fluorouracil. Cover with gauze bandages if necessary, but do not use tight (occlusive) dressings).
Try to keep out of the sun, or wear protective clothing and use a sunscreen when you are outdoors. Do not use sun lamps or sun tanning beds or booths. Fluorouracil makes your skin more sensitive to the sun and you may get a sunburn more easily.