Zafirlukast is used for:
Prevention and long-term treatment of asthma in patients 5 years old and older. Zafirlukast should not be used to treat acute asthma attacks. Zafirlukast may be used for other conditions as determined by your doctor.
Zarfirlukast is a leukotriene receptor antagonist. Zafirlukast works by blocking the action of certain chemicals that are responsible for some forms of asthma.
Do NOT use Zafirlukast if:
- you are allergic to any ingredient in Zafirlukast
Before using Zafirlukast :
Some medical conditions may interact with Zafirlukast . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have a history of liver problems
- if you have a history of mental or mood problems (eg, depression) or suicidal thoughts or actions
- if you are taking a steroid (eg, prednisone)
Some MEDICINES MAY INTERACT with Zafirlukast . Tell your health care provider if you are taking any other medicines, especially any of the following:
- Anticoagulants (eg, warfarin) because the risk of bleeding may be increased by Zafirlukast
- Erythromycin because it may decrease Zafirlukast 's effectiveness
- Certain anticonvulsants (eg, carbamazepine, phenobarbital, phenytoin), calcium channel blockers (eg, amlodipine), cisapride, cyclosporine, theophylline, or tolbutamide because the risk of their side effects may be increased by Zafirlukast
This may not be a complete list of all interactions that may occur. Ask your health care provider if Zafirlukast may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use Zafirlukast :
Use Zafirlukast as directed by your doctor. Check the label on Zafirlukast for exact dosing instructions.
- Take Zafirlukast by mouth on an empty stomach at least 1 hour before or 2 hours after eating.
- Taking Zafirlukast at the same time each day will help you remember to take it.
- Take Zafirlukast on a regular schedule to get the most benefit from it.
- Continue to take Zafirlukast even if you feel well. Do not miss any doses.
- If you miss a dose of Zafirlukast , take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Zafirlukast .
Important safety information:
- Zafirlukast will not stop an asthma attack once one has started. If you are also using a bronchodilator inhaler, be sure to always carry the bronchodilator inhaler with you to use during asthma attacks.
- If your symptoms do not get better or if they get worse, check with your doctor.
- Do not decrease your dose or stop using Zafirlukast or other asthma medicines without first checking with your doctor.
- Zafirlukast may rarely cause severe and sometimes fatal liver problems. Tell your doctor right away if you experience symptoms of liver problems (eg, yellowing of the skin or eyes, dark urine, flu-like symptoms, itching, loss of appetite, persistent nausea or stomach pain, unusual tiredness).
- If your doctor tells you that you have had liver damage because of use of Zafirlukast , do not take Zafirlukast again.
- Some patients taking Zafirlukast have developed mental or mood changes, including suicidal thoughts or actions. Contact your doctor immediately if you experience symptoms such as agitation, aggression, hostility, anxiety, depression, strange dreams, trouble sleeping, sleepwalking, tremor, hallucinations, restlessness, irritability, or any unusual change in mood or behavior. Contact your doctor immediately if any signs of suicidal thoughts or actions occur.
- Lab tests, including liver function, may be performed while you use Zafirlukast . These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
- Use Zafirlukast with caution in the ELDERLY; they may be more sensitive to its effects.
- Zafirlukast should not be used in CHILDREN younger than 5 years old; safety and effectiveness in these children have not been confirmed.
- PREGNANCY AND BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Zafirlukast while you are pregnant. Zafirlukast is found in breast milk. Do not breast-feed while taking Zafirlukast .
Possible side effects of Zafirlukast :
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Diarrhea; headache; nausea.
Seek medical attention right away if any of these SEVERE side effects occur:
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue, unusual hoarseness); burning, numbness, or tingling of the skin, hands, or feet; chest pain; fever, chills, or persistent sore throat; joint or muscle aches and pains; mental or mood changes (eg, agitation, aggression, hostility, anxiety, depression, severe or persistent trouble sleeping, strange dreams, sleepwalking, tremor, hallucinations, restlessness, irritability, any unusual change in behavior); new or worsening shortness of breath or other breathing problems; suicidal thoughts or actions; symptoms of liver problems (eg, yellowing of the skin or eyes, dark urine, flu-like symptoms, itching, loss of appetite, persistent nausea or stomach pain, unusual tiredness); unusual bruising or bleeding.